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Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (22D11) (RVV08636)

Host species:Human
Isotype:IgG1, kappa
Applications:Blocking, ELISA
Accession:P27958(H77); Q9WMX2(CON1); P26660(J6); O39929(ED43); B9V0E2(HK6a); O91936(SA13); A9YFN8(S52)
Overview

Catalog No.

RVV08636

Species reactivity

Hepatitis C virus genotype 1a (isolate H77) (HCV); Hepatitis C virus genotype 1b (isolate Con1) (HCV); Hepatitis C virus genotype 2a (isolate HC-J6) (HCV); Hepatitis C virus S52/JFH1; Hepatitis C virus genotype 4a (isolate ED43) (HCV); Hepatitis C virus genotype 5a (isolate SA13) (HCV); Hepatitis C virus genotype 5a (isolate SA13) (HCV)

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P27958(H77); Q9WMX2(CON1); P26660(J6); O39929(ED43); B9V0E2(HK6a); O91936(SA13); A9YFN8(S52)

Applications

Blocking, ELISA

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

22D11

Data Image
  • SDS-PAGE
    SDS PAGE for HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (22D11)
References

HCV Proteins Modulate the Host Cell miRNA Expression Contributing to Hepatitis C Pathogenesis and Hepatocellular Carcinoma Development. PMID: 34069740

Expression of MBP-HCV NS1/E2 fusion protein in E. coli and detection of anti-NS1/E2 antibody in type C chronic liver disease. PMID: 1314578

Expression of HCV E2/NS1 protein as a fusion protein with maltose binding protein: detection of anti-E2/NS1 antibody in chronic liver disease. PMID: 7686121

Roles of secretory glycoproteins in particle formation of Flaviviridae viruses. PMID: 31342548

Variable and hypervariable domains are found in the regions of HCV corresponding to the flavivirus envelope and NS1 proteins and the pestivirus envelope glycoproteins. PMID: 1846505

[Hepatitis C]. PMID: 8345654

Hepatitis C and liver transplantation. PMID: 8527717

Degree and distribution of variability in the 5' untranslated, E1, E2/NS1 and NS5 regions of the hepatitis C virus (HCV). PMID: 9751009

Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins. PMID: 28991176

Antibody response to E2/NS1 hepatitis C virus protein in patients with acute hepatitis C. PMID: 9076628

Viral Interference Between Dengue Virus and Hepatitis C Virus Infections. PMID: 32875000

[Hepatitis C immunology]. PMID: 10614142

Secretion and purification of hepatitis C virus NS1 glycoprotein produced by recombinant baculovirus-infected insect cells. PMID: 7686870

Significance of anti-E2 in the diagnosis of HCV infection in patients on maintenance hemodialysis: anti-E2 is frequently detected among anti-HCV antibody-negative patients. PMID: 8959633

Viral loads and E2/NS1 region sequences of hepatitis C virus in hepatocellular carcinoma and surrounding liver. PMID: 9159034

Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae. PMID: 28644867

Expression and purification of E2/NS1 protein of hepatitis C virus and detection of anti-E2/NS1 antibodies in chronic liver disease patients. PMID: 12595764

Expression of the amino-terminal half of the NS1 region of the hepatitis C virus genome and detection of an antibody to the expressed protein in patients with liver diseases. PMID: 1379627

Syntheses of immunodominant peptide regions of hepatitis C viral pathogens using PS-BDODMA resin: a single peptide derived from the conserved domain (E2/NS1) was highly effective in detecting anti-HCV antibodies. PMID: 11168897

[Evolution of hepatitis C virus (HCV) viremia and adaptation of HCV in persistent infection in patients with acute hepatitis]. PMID: 7521430

[Significance of polypeptide antigen of HCVE2/NS1 relative conservation region in detection of anti-HCV]. PMID: 12759957

Natural history of hepatitis C. PMID: 7529217

Epidemiological studies on hepatitis C virus infection: detection, prevalence, exposure and prevention. PMID: 7814243

Development and Evaluation of a Universal and Supersensitive NS1-Based Luciferase Immunosorbent Assay to Detect Zika Virus-Specific IgG. PMID: 31552611

Structure, genomic organization, replication and variability of hepatitis C virus. PMID: 8918741

Sequence uniqueness and sequence variability as modulating factors of human anti-HCV humoral immune response. PMID: 18256830

[Fundamental studies of hepatitis C virus: a review]. PMID: 1331574

Genomic typing of hepatitis C viruses from Korean patients: implications of genome variation in the E2/NS1 region. PMID: 8240354

Partial nucleotide sequence analysis of a French hepatitis C virus: implications for HCV genetic variability in the E2/NS1 protein. PMID: 1655961

Expression of structural proteins of hepatitis C virus (HCV) in mammalian cells. PMID: 18726270

Translation-competent 48S complex formation on HCV IRES requires the RNA-binding protein NSAP1. PMID: 21715376

[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy in relation to clinical course]. PMID: 7521410

Use of a novel hepatitis C virus (HCV) major-epitope chimeric polypeptide for diagnosis of HCV infection. PMID: 10203493

Hepatitis C transmission between spouses. PMID: 8985816

[Genomic changes in the E2/NS1 region of HCV before and after IFN therapy]. PMID: 7563902

[Innate immune responses against viral infection and its suppression by viral proteins]. PMID: 23449408

Hypervariable 5'-terminus of hepatitis C virus E2/NS1 encodes antigenically distinct variants. PMID: 7689636

Variability of the E2/NS1 region of Swedish hepatitis C virus strains and its correlation to genotypes. PMID: 7939424

A novel antigen detection immunoassay for field diagnosis of hepatitis C virus infection. PMID: 14677657

Analysis of hepatitis C virus capsid, E1, and E2/NS1 proteins expressed in insect cells. PMID: 8212557

Comparison between homologies of E2/NS1 gene from genotype III Chinese isolates of hepatitis C virus and that from reported isolates. PMID: 11155671

Confirmation of hepatitis C infection: a comparison of five immunoblot assays. PMID: 7519796

[Molecular genotypes of hepatitis C virus and their divergence times]. PMID: 8385234

Low-level hepatitis C viremia and humoral immune response to NS4 in chronic hepatitis B virus-hepatitis C virus coinfection. PMID: 15513365

Hepatitis C virus-related proteins in kidney tissue from hepatitis C virus-infected patients with cryoglobulinemic membranoproliferative glomerulonephritis. PMID: 9141444

Hepatitis C virus transmission in a pediatric oncology ward: analysis of an outbreak and review of the literature. PMID: 11310819

Influence of antibodies to the hypervariable region of E2/NS1 glycoprotein on the selective replication of hepatitis C virus in chimpanzees. PMID: 7941335

Quantitative analysis of antibody to hepatitis C virus envelope 2 glycoprotein in patients with chronic hepatitis C virus infection. PMID: 8621173

[Expression of hepatitis C virus genome]. PMID: 7681882

Structure of the hepatitis C virus E1E2 glycoprotein complex. PMID: 36264808

[Tropism of hepatitis C virus for leukocytes-- importance of the analysis of viral E1 and E2 envelope glycoprotein genes by sequencing]. PMID: 19892492

Structure of a pestivirus envelope glycoprotein E2 clarifies its role in cell entry. PMID: 23273918

Identification of new functional regions in hepatitis C virus envelope glycoprotein E2. PMID: 21147916

Hepatitis C virus envelope glycoprotein E2 glycans modulate entry, CD81 binding, and neutralization. PMID: 17507469

A model for the hepatitis C virus envelope glycoprotein E2. PMID: 10861927

Computational Modeling of Hepatitis C Virus Envelope Glycoprotein Structure and Recognition. PMID: 29892287

The Alphavirus E2 Membrane-Proximal Domain Impacts Capsid Interaction and Glycoprotein Lattice Formation. PMID: 30463969

The envelope glycoprotein E2 is a determinant of cell culture tropism in ruminant pestiviruses. PMID: 12692293

The GBV-C envelope glycoprotein E2 does not interact specifically with CD81. PMID: 17457101

Structural Glycoprotein E2 of Classical Swine Fever Virus Critically Interacts with Host Protein Torsin-1A during the Virus Infectious Cycle. PMID: 33827941

Differential interaction strategies of hepatitis c virus genotypes during entry - An in silico investigation of envelope glycoprotein E2 - CD81 interaction. PMID: 30639544

Interaction of the most membranotropic region of the HCV E2 envelope glycoprotein with membranes. Biophysical characterization. PMID: 18339752

Novel E2 Glycoprotein Tetramer Detects Hepatitis C Virus-Specific Memory B Cells. PMID: 27849172

Production and characterization of the ectodomain of E2 envelope glycoprotein of hepatitis C virus folded in the presence of full-length E1 glycoprotein. PMID: 25255721

P108 and T109 on E2 Glycoprotein Domain I Are Critical for the Adaptation of Classical Swine Fever Virus to Rabbits but Not for Virulence in Pigs. PMID: 32581110

Molecular links between the E2 envelope glycoprotein and nucleocapsid core in Sindbis virus. PMID: 22001018

Preliminary mapping of non-conserved epitopes on envelope glycoprotein E2 of Bovine viral diarrhea virus type 1 and 2. PMID: 23838147

Structure and Function of the Hepatitis C Virus Envelope Glycoproteins E1 and E2: Antiviral and Vaccine Targets. PMID: 27933781

An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry. PMID: 28031364

Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33. PMID: 22973046

Identification of glycosaminoglycan-binding sites within hepatitis C virus envelope glycoprotein E2*. PMID: 16255759

Retention and topology of the bovine viral diarrhea virus glycoprotein E2. PMID: 28874234

Crystal structure of glycoprotein E2 from bovine viral diarrhea virus. PMID: 23569276

Fusogenic properties of the Ectodomain of HCV E2 envelope protein. PMID: 29273334

The E2 glycoprotein is necessary but not sufficient for the adaptation of classical swine fever virus lapinized vaccine C-strain to the rabbit. PMID: 29734043

Budding of alphaviruses. PMID: 15567491

Expression, purification and crystallization of the ectodomain of the envelope glycoprotein E2 from Bovine viral diarrhoea virus. PMID: 23295482

Overcoming Challenges of Hepatitis C Virus Envelope Glycoprotein Production in Mammalian Cells. PMID: 30593635

Structural characterization of the E2 glycoprotein from Sindbis by lysine biotinylation and LC-MS/MS. PMID: 16443253

The dynamic envelope of a fusion class II virus. E3 domain of glycoprotein E2 precursor in Semliki Forest virus provides a unique contact with the fusion protein E1. PMID: 18596032

Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis. PMID: 29253863

Identification of conserved residues in the E2 envelope glycoprotein of the hepatitis C virus that are critical for CD81 binding. PMID: 16912317

Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion. PMID: 26246575

An Alphavirus E2 Membrane-Proximal Domain Promotes Envelope Protein Lateral Interactions and Virus Budding. PMID: 29114027

Production and characterization of mouse monoclonal antibodies reactive to Chikungunya envelope E2 glycoprotein. PMID: 17949772

Simultaneous Quantification of Hepatitis C Virus Envelope Glycoproteins E1 and E2 by Dual-Color Fluorescence Immunoblot Analysis. PMID: 30593634

Expression of unmodified hepatitis C virus envelope glycoprotein-coding sequences leads to cryptic intron excision and cell surface expression of E1/E2 heterodimers comprising full-length and partially deleted E1. PMID: 14645599

The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral Attenuation and Protection against Lethal Challenge. PMID: 34730400

Plant-made E2 glycoprotein single-dose vaccine protects pigs against classical swine fever. PMID: 29993179

Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly. PMID: 28179528

Assembly of a functional HCV glycoprotein heterodimer. PMID: 17489436

Structure-function analysis of hepatitis C virus envelope glycoproteins E1 and E2. PMID: 25245635

Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses. PMID: 24725935

Vector infection determinants of Venezuelan equine encephalitis virus reside within the E2 envelope glycoprotein. PMID: 12021373

Identification of structural motifs in the E2 glycoprotein of Chikungunya involved in virus-host interaction. PMID: 23025271

HCV E2 glycoprotein: mutagenesis of N-linked glycosylation sites and its effects on E2 expression and processing. PMID: 14967486

HCV glycoprotein structures: what to expect from the unexpected. PMID: 25790756

MARCH8 Targets Cytoplasmic Lysine Residues of Various Viral Envelope Glycoproteins. PMID: 35019698

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-HCV NS1/gp68/gp70/Envelope glycoprotein E2 Antibody (22D11) [RVV08636]
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