Catalog No.
RVV08635
Species reactivity
Hepatitis C virus genotype 1a (isolate H77) (HCV); Hepatitis C virus genotype 1b (isolate Con1) (HCV); Hepatitis C virus genotype 2a (isolate HC-J6) (HCV); Hepatitis C virus S52/JFH1; Hepatitis C virus genotype 4a (isolate ED43) (HCV); Hepatitis C virus genotype 5a (isolate SA13) (HCV); Hepatitis C virus genotype 5a (isolate SA13) (HCV)
Host species
Human
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
NS1, gp68, gp70, Envelope glycoprotein E2, Genome polyprotein
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P27958(H77); Q9WMX2(CON1); P26660(J6); O39929(ED43); B9V0E2(HK6a); O91936(SA13); A9YFN8(S52)
Applications
Blocking, ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
19B3
Structure of the hepatitis C virus E1E2 glycoprotein complex. PMID: 36264808
[Tropism of hepatitis C virus for leukocytes-- importance of the analysis of viral E1 and E2 envelope glycoprotein genes by sequencing]. PMID: 19892492
Structure of a pestivirus envelope glycoprotein E2 clarifies its role in cell entry. PMID: 23273918
Identification of new functional regions in hepatitis C virus envelope glycoprotein E2. PMID: 21147916
Hepatitis C virus envelope glycoprotein E2 glycans modulate entry, CD81 binding, and neutralization. PMID: 17507469
A model for the hepatitis C virus envelope glycoprotein E2. PMID: 10861927
Computational Modeling of Hepatitis C Virus Envelope Glycoprotein Structure and Recognition. PMID: 29892287
The Alphavirus E2 Membrane-Proximal Domain Impacts Capsid Interaction and Glycoprotein Lattice Formation. PMID: 30463969
The envelope glycoprotein E2 is a determinant of cell culture tropism in ruminant pestiviruses. PMID: 12692293
The GBV-C envelope glycoprotein E2 does not interact specifically with CD81. PMID: 17457101
Structural Glycoprotein E2 of Classical Swine Fever Virus Critically Interacts with Host Protein Torsin-1A during the Virus Infectious Cycle. PMID: 33827941
Differential interaction strategies of hepatitis c virus genotypes during entry - An in silico investigation of envelope glycoprotein E2 - CD81 interaction. PMID: 30639544
Interaction of the most membranotropic region of the HCV E2 envelope glycoprotein with membranes. Biophysical characterization. PMID: 18339752
Novel E2 Glycoprotein Tetramer Detects Hepatitis C Virus-Specific Memory B Cells. PMID: 27849172
Production and characterization of the ectodomain of E2 envelope glycoprotein of hepatitis C virus folded in the presence of full-length E1 glycoprotein. PMID: 25255721
P108 and T109 on E2 Glycoprotein Domain I Are Critical for the Adaptation of Classical Swine Fever Virus to Rabbits but Not for Virulence in Pigs. PMID: 32581110
Molecular links between the E2 envelope glycoprotein and nucleocapsid core in Sindbis virus. PMID: 22001018
Preliminary mapping of non-conserved epitopes on envelope glycoprotein E2 of Bovine viral diarrhea virus type 1 and 2. PMID: 23838147
Structure and Function of the Hepatitis C Virus Envelope Glycoproteins E1 and E2: Antiviral and Vaccine Targets. PMID: 27933781
An Optimized Hepatitis C Virus E2 Glycoprotein Core Adopts a Functional Homodimer That Efficiently Blocks Virus Entry. PMID: 28031364
Structure of hepatitis C virus envelope glycoprotein E2 antigenic site 412 to 423 in complex with antibody AP33. PMID: 22973046
Identification of glycosaminoglycan-binding sites within hepatitis C virus envelope glycoprotein E2*. PMID: 16255759
Retention and topology of the bovine viral diarrhea virus glycoprotein E2. PMID: 28874234
Crystal structure of glycoprotein E2 from bovine viral diarrhea virus. PMID: 23569276
Fusogenic properties of the Ectodomain of HCV E2 envelope protein. PMID: 29273334
The E2 glycoprotein is necessary but not sufficient for the adaptation of classical swine fever virus lapinized vaccine C-strain to the rabbit. PMID: 29734043
Budding of alphaviruses. PMID: 15567491
Expression, purification and crystallization of the ectodomain of the envelope glycoprotein E2 from Bovine viral diarrhoea virus. PMID: 23295482
Overcoming Challenges of Hepatitis C Virus Envelope Glycoprotein Production in Mammalian Cells. PMID: 30593635
Structural characterization of the E2 glycoprotein from Sindbis by lysine biotinylation and LC-MS/MS. PMID: 16443253
The dynamic envelope of a fusion class II virus. E3 domain of glycoprotein E2 precursor in Semliki Forest virus provides a unique contact with the fusion protein E1. PMID: 18596032
Probing the antigenicity of hepatitis C virus envelope glycoprotein complex by high-throughput mutagenesis. PMID: 29253863
Identification of conserved residues in the E2 envelope glycoprotein of the hepatitis C virus that are critical for CD81 binding. PMID: 16912317
Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion. PMID: 26246575
An Alphavirus E2 Membrane-Proximal Domain Promotes Envelope Protein Lateral Interactions and Virus Budding. PMID: 29114027
Production and characterization of mouse monoclonal antibodies reactive to Chikungunya envelope E2 glycoprotein. PMID: 17949772
Simultaneous Quantification of Hepatitis C Virus Envelope Glycoproteins E1 and E2 by Dual-Color Fluorescence Immunoblot Analysis. PMID: 30593634
Expression of unmodified hepatitis C virus envelope glycoprotein-coding sequences leads to cryptic intron excision and cell surface expression of E1/E2 heterodimers comprising full-length and partially deleted E1. PMID: 14645599
The Unique Glycosylation at Position 986 on the E2 Glycoprotein of Classical Swine Fever Virus Is Responsible for Viral Attenuation and Protection against Lethal Challenge. PMID: 34730400
Plant-made E2 glycoprotein single-dose vaccine protects pigs against classical swine fever. PMID: 29993179
Identification of Novel Functions for Hepatitis C Virus Envelope Glycoprotein E1 in Virus Entry and Assembly. PMID: 28179528
Assembly of a functional HCV glycoprotein heterodimer. PMID: 17489436
Structure-function analysis of hepatitis C virus envelope glycoproteins E1 and E2. PMID: 25245635
Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses. PMID: 24725935
Vector infection determinants of Venezuelan equine encephalitis virus reside within the E2 envelope glycoprotein. PMID: 12021373
Identification of structural motifs in the E2 glycoprotein of Chikungunya involved in virus-host interaction. PMID: 23025271
HCV E2 glycoprotein: mutagenesis of N-linked glycosylation sites and its effects on E2 expression and processing. PMID: 14967486
HCV glycoprotein structures: what to expect from the unexpected. PMID: 25790756
MARCH8 Targets Cytoplasmic Lysine Residues of Various Viral Envelope Glycoproteins. PMID: 35019698
A magnetoelastic biosensor based on E2 glycoprotein for wireless detection of classical swine fever virus E2 antibody. PMID: 29142249
Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses. PMID: 8411378
Structural elucidation of critical residues involved in binding of human monoclonal antibodies to hepatitis C virus E2 envelope glycoprotein. PMID: 18230369
Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein. PMID: 22457519
Glycan Shielding and Modulation of Hepatitis C Virus Neutralizing Antibodies. PMID: 29755477
GB virus C E2 glycoprotein: expression in CHO cells, purification and characterization. PMID: 9266979
The hypervariable region 1 of the E2 glycoprotein of hepatitis C virus binds to glycosaminoglycans, but this binding does not lead to infection in a pseudotype system. PMID: 15078928
Glycoprotein E2 of classical swine fever virus: expression in insect cells and identification as a ribonuclease. PMID: 8178442
Efficacy of E2 glycoprotein fused to porcine CD154 as a novel chimeric subunit vaccine to prevent classical swine fever virus vertical transmission in pregnant sows. PMID: 28622852
HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells. PMID: 23053572
Presentation of the hydrophilic domains of hepatitis C viral E2 envelope glycoprotein on hepatitis B surface antigen particles. PMID: 8915880
The pestivirus E(rns) glycoprotein interacts with E2 in both infected cells and mature virions. PMID: 14554096
HCV Broadly Neutralizing Antibodies Use a CDRH3 Disulfide Motif to Recognize an E2 Glycoprotein Site that Can Be Targeted for Vaccine Design. PMID: 30439340
Hepatitis C virus envelope protein E2 binds to CD81 of tamarins. PMID: 11080483
Hepatitis C Virus Structure: Defined by What It Is Not. PMID: 31501263
Disulfide bonds in hepatitis C virus glycoprotein E1 control the assembly and entry functions of E2 glycoprotein. PMID: 23175356
Crystal structure of the pestivirus envelope glycoprotein E(rns) and mechanistic analysis of its ribonuclease activity. PMID: 22579253
For research use only. Not for human or drug use.
