Dementia risk and prevention by targeting modifiable vascular risk factors. PMID: 28734089
Binding characteristics and antitumor properties of 1A10 bispecific antibody recognizing gp40 and human transferrin receptor. PMID: 8548750
Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region. PMID: 12847094
Evaluation of inhibitors of intestinal UDP-glucuronosyltransferases 1A8 and 1A10 using raloxifene as a substrate in Caco-2 cells: Studies with four flavonoids of Scutellaria baicalensis. PMID: 33440186
Coordinate regulation of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 genes by hepatocyte nuclear factor 1alpha and the caudal-related homeodomain protein 2. PMID: 15044625
Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10. PMID: 29421866
Oligomerization and Catalytic Parameters of Human UDP-Glucuronosyltransferase 1A10: Expression and Characterization of the Recombinant Protein. PMID: 30111624
UDP-glucuronosyltransferases 1A6 and 1A10 catalyze reduced menadione glucuronidation. PMID: 18423374
Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. PMID: 17981312
Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues. PMID: 18374377
Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10. PMID: 19116261
Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10. PMID: 17638922
Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element. PMID: 29519853
Epigenetic regulation of the tissue-specific expression of human UDP-glucuronosyltransferase (UGT) 1A10. PMID: 24239897
Prevention of Sport-related Facial Injuries. PMID: 28314416
Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10. PMID: 25547628
In silico modeling of UDP-glucuronosyltransferase 1A10 substrates using the VolSurf approach. PMID: 22388963
UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility. PMID: 20007297
Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation. PMID: 15117964
Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs. PMID: 35275773
Murine bispecific antibody 1A10 directed to human transferrin receptor and a 42-kDa tumor-associated glycoprotein. PMID: 8625561
Epidemiology of Facial Injuries in Sport. PMID: 28314415
Mapping the UDP-glucuronic acid binding site in UDP-glucuronosyltransferase-1A10 by homology-based modeling: confirmation with biochemical evidence. PMID: 18570380
Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform. PMID: 16510539
1-Alpha, 25-dihydroxyvitamin D3 alters the pharmacokinetics of mycophenolic acid in renal transplant recipients by regulating two extrahepatic UDP-glucuronosyltransferases 1A8 and 1A10. PMID: 27496319
Prominent but reverse stereoselectivity in propranolol glucuronidation by human UDP-glucuronosyltransferases 1A9 and 1A10. PMID: 16763014
Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent. PMID: 23372764
Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10. PMID: 17174996
Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin. PMID: 18725508
Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10. PMID: 10497143
Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10. PMID: 19486934
The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis. PMID: 18048489
Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10. PMID: 20053997
Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10. PMID: 12695339
Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis. PMID: 16475821
Amino acid residue ILE211 is essential for the enzymatic activity of human UDP-glucuronosyltransferase 1A10 (UGT1A10). PMID: 15039300
Transcriptional regulation of human UDP-glucuronosyltransferase genes. PMID: 25336387
Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. PMID: 26875642
Glucuronidation of D-Luciferin In Vitro: Isoform Selectivity and Kinetics Characterization. PMID: 30820844
[Impact of intestinal metabolism on drug development]. PMID: 19749486
Moral cognition and its neural constituents. PMID: 14523383
Validity of administrative data in recording sepsis: a systematic review. PMID: 25887596
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract. PMID: 15364550
A new isoflavone glycoside from Pueraria alopecuroides. PMID: 26525177
Inhibition of UDP-glucuronosyltransferases (UGTs) by phthalate monoesters. PMID: 29328989
Near-infrared measurements of brain oxygenation in stroke. PMID: 26958577
In vitro effects of opicapone on activity of human UDP-glucuronosyltransferases isoforms. PMID: 35810997
Characterizations of Human UDP-Glucuronosyltransferase Enzymes in the Conjugation of p-Cresol. PMID: 32421801
Glucuronidation and its impact on the bioactivity of [6]-shogaol. PMID: 28503853
Identification of UDP-glucuronosyltransferases involved in the metabolism of silymarin flavonolignans. PMID: 31727359
Mental Health and Addiction Related Emergency Department Visits: A Systematic Review of Qualitative Studies. PMID: 34075518
Prominent Stereoselectivity of NNAL Glucuronidation in Upper Aerodigestive Tract Tissues. PMID: 31307193
Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT). PMID: 23362865
Potential interactions among myricetin and dietary flavonols through the inhibition of human UDP-glucuronosyltransferase in vitro. PMID: 35063619
The health equity curse: ethical tensions in promoting health equity. PMID: 34407781
In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver. PMID: 33446524
Signs and symptoms of the postictal period in epilepsy: A systematic review and meta-analysis. PMID: 30978637
Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases. PMID: 29470958
How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10? PMID: 20089735
Molecular and functional characterization of UDP-glucuronosyltransferase 1A in cynomolgus macaques. PMID: 29944869
Structure- and isoform-specific glucuronidation of six curcumin analogs. PMID: 27324181
Evaluation of human primary intestinal monolayers for drug metabolizing capabilities. PMID: 31709009
[Inhibition of sciadopitysin against UDP-glucuronosyltransferases]. PMID: 29874021
A New Vaccine Candidate Expressing JUNV GP1-GP2 Against Argentine Hemorrhagic Fever Based on Baculovirus Surface Display., PMID:40514553
Scalable Production of Recombinant Vesicular Stomatitis Virus Pseudoparticles Using HEK293 Suspension Cultures., PMID:40462709
Designed miniproteins potently inhibit and protect against MERS-CoV., PMID:40450691
Single dose VSV-based vaccine protects mice against lethal heterologous Crimean-Congo hemorrhagic fever virus challenge., PMID:40447644
Past, Present, and Future of Viral Vector Vaccine Platforms: A Comprehensive Review., PMID:40432133
Evaluating Neutralizing Antibodies in Hantavirus-Infected Patients Using Authentic Virus and Recombinant Vesicular Stomatitis Virus Systems., PMID:40431735
Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies., PMID:40403696
A Brighton Collaboration standardized template with key considerations for a benefit/risk assessment for the emergent vesicular stomatitis virus (VSV) viral vector vaccine for Lassa fever., PMID:40367816
Comparison of the induction of neutralizing antibodies against Bas congo virus using several vaccine modalities., PMID:40348847
Establishment of a pseudovirus neutralization assay for TGEV., PMID:40276514
The Pseudotyped Replication-Deficient VSV with Spike from PEDV Induces Neutralizing Antibody Against PEDV., PMID:40266086
Simian Immunodeficiency Virus-Based Virus-like Particles Are an Efficient Tool to Induce Persistent Anti-SARS-CoV-2 Spike Neutralizing Antibodies and Specific T Cells in Mice., PMID:40266067
Single-dose VSV-Sudan virus vaccine protects from lethal Sudan virus infection within one week: a challenge study in macaques., PMID:40196593
Membrane-targeted immunogenic compositions using exosome mimetic approach for vaccine development against SARS-CoV-2 and other pathogens., PMID:40157987
Preclinical development of a replication-competent vesicular stomatitis virus-based Lassa virus vaccine candidate advanced into human clinical trials., PMID:40157130
A VSV-based oral rabies vaccine was sentineled by Peyer's patches and induced a timely and durable immune response., PMID:40022445
Tim-3 promotes viral infection by suppressing the USP25-TRAF3-IRF7 signaling pathway., PMID:39946759
Standardization, validation, and comparative evaluation of a convenient surrogate recombinant vesicular stomatitis virus plaque reduction test for quantification of Hantaan orthohantavirus (HTNV) neutralizing antibodies., PMID:39923054
Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses., PMID:39922192
Development and application of a high-titer VSV-based HCoV-NL63 pseudovirus system via C-terminal 14 amino acid truncation of spike., PMID:39922054
Replication-incompetent VSV-based vaccine elicits protective responses against SARS-CoV-2 and influenza virus., PMID:39879304
Short-term oral exposure to nanoplastics does not significantly impact the antiviral immune response of the mouse., PMID:39854993
A hTfR1 Receptor-Specific VHH Antibody Neutralizes Pseudoviruses Expressing Glycoproteins from Junín and Machupo Viruses., PMID:39772257
PD1-Targeted Transgene Delivery to Treg Cells., PMID:39772246
A Global Collaborative Comparison of SARS-CoV-2 Antigenicity Across 15 Laboratories., PMID:39772242
Safety, Immunogenicity, and Efficacy of a Recombinant Vesicular Stomatitis Virus Vectored Vaccine Against Severe Fever with Thrombocytopenia Syndrome Virus and Heartland Bandavirus., PMID:39772063
A surrogate BSL2-compliant infection model recapitulating key aspects of human Marburg virus disease., PMID:39745141
Vesicular Stomatitis Virus Transmission Dynamics Within Its Endemic Range in Chiapas, Mexico., PMID:39599856
Quantification of Neutralizing Antibodies in Serum Using VSV-MARV-GFP., PMID:39585633
Serosurvey of Arboviruses in Free-Ranging Mantled Howler Monkeys (Alouatta palliata) in Costa Rica., PMID:39573905
Assessment of Single-Cycle M-Protein Mutated Vesicular Stomatitis Virus as a Safe and Immunogenic Mucosal Vaccine Platform for SARS-CoV-2 Immunogen Delivery., PMID:39526809
Avian TRIM13 attenuates antiviral innate immunity by targeting MAVS for autophagic degradation., PMID:39508267
Cellular NONO protein binds to the flavivirus replication complex and promotes positive-strand RNA synthesis., PMID:39499073
Intranasal Prime-Boost with Spike Vectors Generates Antibody and T-Cell Responses at the Site of SARS-CoV-2 Infection., PMID:39460356
Improved efficacy of SARS-CoV-2 isolation from COVID-19 clinical specimens using VeroE6 cells overexpressing TMPRSS2 and human ACE2., PMID:39438626
Protocol for constructing and characterizing recombinant vectored vaccines for rabies virus., PMID:39423123
Development of pseudotyped VSV-SARS-CoV-2 spike variants for the assessment of neutralizing antibodies., PMID:39411978
Enhancing the Efficacy of Breast Cancer Immunotherapy Using a Smac-Armed Oncolytic Virus., PMID:39409870
Immunogenicity and Neutralization of Recombinant Vaccine Candidates Expressing F and G Glycoproteins against Nipah Virus., PMID:39340029
The Autonomous Fusion Activity of Human Cytomegalovirus Glycoprotein B Is Regulated by Its Carboxy-Terminal Domain., PMID:39339958
Bats generate lower affinity but higher diversity antibody responses than those of mice, but pathogen-binding capacity increases if protein is restricted in their diet., PMID:39316608
CD40 stimulation activates CD8+ T cells and controls HBV in CD4-depleted mice., PMID:39282227
Metformin facilitates viral reservoir reactivation and their recognition by anti-HIV-1 envelope antibodies., PMID:39252967
Efficacy and Immunogenicity of a Recombinant Vesicular Stomatitis Virus-Vectored Marburg Vaccine in Cynomolgus Macaques., PMID:39205155
Vaccine Platform Comparison: Protective Efficacy against Lethal Marburg Virus Challenge in the Hamster Model., PMID:39126087
Replication, safety and immunogenicity of the vectored Ebola vaccine rVSV-ΔG-ZEBOV-GP in a sub-Saharan African paediatric population: A randomised controlled, open-label trial in children aged 1-12 years living in Lambaréné, Gabon., PMID:39121969
Mosaic neuraminidase-based vaccine induces antigen-specific T cell responses against homologous and heterologous influenza viruses., PMID:39117282
Evaluation of a novel intramuscular prime/intranasal boost vaccination strategy against influenza in the pig model., PMID:39116029
Surveillance of Feral Swine (Sus scrofa) in the Western USA for Antibodies to Vesicular Stomatitis Virus, 2013-21., PMID:39074817
Characteristics and Functions of Infection-enhancing Antibodies to the N-terminal Domain of SARS-CoV-2., PMID:38933606
For research use only. Not for human or drug use.
