Dementia risk and prevention by targeting modifiable vascular risk factors. PMID: 28734089
Binding characteristics and antitumor properties of 1A10 bispecific antibody recognizing gp40 and human transferrin receptor. PMID: 8548750
Cloning and characterization of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 gene promoters: differential regulation through an interior-like region. PMID: 12847094
Evaluation of inhibitors of intestinal UDP-glucuronosyltransferases 1A8 and 1A10 using raloxifene as a substrate in Caco-2 cells: Studies with four flavonoids of Scutellaria baicalensis. PMID: 33440186
Coordinate regulation of the human UDP-glucuronosyltransferase 1A8, 1A9, and 1A10 genes by hepatocyte nuclear factor 1alpha and the caudal-related homeodomain protein 2. PMID: 15044625
Molecular Docking-Based Design and Development of a Highly Selective Probe Substrate for UDP-glucuronosyltransferase 1A10. PMID: 29421866
Oligomerization and Catalytic Parameters of Human UDP-Glucuronosyltransferase 1A10: Expression and Characterization of the Recombinant Protein. PMID: 30111624
UDP-glucuronosyltransferases 1A6 and 1A10 catalyze reduced menadione glucuronidation. PMID: 18423374
Novel identification of UDP-glucuronosyltransferase 1A10 as an estrogen-regulated target gene. PMID: 17981312
Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues. PMID: 18374377
Dopamine is a low-affinity and high-specificity substrate for the human UDP-glucuronosyltransferase 1A10. PMID: 19116261
Glucuronidation of PhIP and N-OH-PhIP by UDP-glucuronosyltransferase 1A10. PMID: 17638922
Cooperative Regulation of Intestinal UDP-Glucuronosyltransferases 1A8, -1A9, and 1A10 by CDX2 and HNF4α Is Mediated by a Novel Composite Regulatory Element. PMID: 29519853
Epigenetic regulation of the tissue-specific expression of human UDP-glucuronosyltransferase (UGT) 1A10. PMID: 24239897
Prevention of Sport-related Facial Injuries. PMID: 28314416
Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10. PMID: 25547628
In silico modeling of UDP-glucuronosyltransferase 1A10 substrates using the VolSurf approach. PMID: 22388963
UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility. PMID: 20007297
Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation. PMID: 15117964
Regulation of human UDP-glycosyltransferase (UGT) genes by miRNAs. PMID: 35275773
Murine bispecific antibody 1A10 directed to human transferrin receptor and a 42-kDa tumor-associated glycoprotein. PMID: 8625561
Epidemiology of Facial Injuries in Sport. PMID: 28314415
Mapping the UDP-glucuronic acid binding site in UDP-glucuronosyltransferase-1A10 by homology-based modeling: confirmation with biochemical evidence. PMID: 18570380
Importance of UDP-glucuronosyltransferase 1A10 (UGT1A10) in the detoxification of polycyclic aromatic hydrocarbons: decreased glucuronidative activity of the UGT1A10139Lys isoform. PMID: 16510539
1-Alpha, 25-dihydroxyvitamin D3 alters the pharmacokinetics of mycophenolic acid in renal transplant recipients by regulating two extrahepatic UDP-glucuronosyltransferases 1A8 and 1A10. PMID: 27496319
Prominent but reverse stereoselectivity in propranolol glucuronidation by human UDP-glucuronosyltransferases 1A9 and 1A10. PMID: 16763014
Albumin stimulates the activity of the human UDP-glucuronosyltransferases 1A7, 1A8, 1A10, 2A1 and 2B15, but the effects are enzyme and substrate dependent. PMID: 23372764
Phenylalanine(90) and phenylalanine(93) are crucial amino acids within the estrogen binding site of the human UDP-glucuronosyltransferase 1A10. PMID: 17174996
Identification of hydroxywarfarin binding site in human UDP glucuronosyltransferase 1a10: phenylalanine90 is crucial for the glucuronidation of 6- and 7-hydroxywarfarin but not 8-hydroxywarfarin. PMID: 18725508
Studies on the substrate specificity of human intestinal UDP- lucuronosyltransferases 1A8 and 1A10. PMID: 10497143
Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10. PMID: 19486934
The first aspartic acid of the DQxD motif for human UDP-glucuronosyltransferase 1A10 interacts with UDP-glucuronic acid during catalysis. PMID: 18048489
Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10. PMID: 20053997
Functional characterization of wild-type and variant (T202I and M59I) human UDP-glucuronosyltransferase 1A10. PMID: 12695339
Phenylalanine 90 and 93 are localized within the phenol binding site of human UDP-glucuronosyltransferase 1A10 as determined by photoaffinity labeling, mass spectrometry, and site-directed mutagenesis. PMID: 16475821
Amino acid residue ILE211 is essential for the enzymatic activity of human UDP-glucuronosyltransferase 1A10 (UGT1A10). PMID: 15039300
Transcriptional regulation of human UDP-glucuronosyltransferase genes. PMID: 25336387
Assessment of the inhibition potential of Licochalcone A against human UDP-glucuronosyltransferases. PMID: 26875642
Glucuronidation of D-Luciferin In Vitro: Isoform Selectivity and Kinetics Characterization. PMID: 30820844
[Impact of intestinal metabolism on drug development]. PMID: 19749486
Moral cognition and its neural constituents. PMID: 14523383
Validity of administrative data in recording sepsis: a systematic review. PMID: 25887596
Regulation of UDP glucuronosyltransferases in the gastrointestinal tract. PMID: 15364550
A new isoflavone glycoside from Pueraria alopecuroides. PMID: 26525177
Inhibition of UDP-glucuronosyltransferases (UGTs) by phthalate monoesters. PMID: 29328989
Near-infrared measurements of brain oxygenation in stroke. PMID: 26958577
In vitro effects of opicapone on activity of human UDP-glucuronosyltransferases isoforms. PMID: 35810997
Characterizations of Human UDP-Glucuronosyltransferase Enzymes in the Conjugation of p-Cresol. PMID: 32421801
Glucuronidation and its impact on the bioactivity of [6]-shogaol. PMID: 28503853
Identification of UDP-glucuronosyltransferases involved in the metabolism of silymarin flavonolignans. PMID: 31727359
Mental Health and Addiction Related Emergency Department Visits: A Systematic Review of Qualitative Studies. PMID: 34075518
Prominent Stereoselectivity of NNAL Glucuronidation in Upper Aerodigestive Tract Tissues. PMID: 31307193
Renal drug metabolism in humans: the potential for drug-endobiotic interactions involving cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT). PMID: 23362865
Potential interactions among myricetin and dietary flavonols through the inhibition of human UDP-glucuronosyltransferase in vitro. PMID: 35063619
The health equity curse: ethical tensions in promoting health equity. PMID: 34407781
In Vitro Evidence of Potential Interactions between CYP2C8 and Candesartan Acyl-β-D-glucuronide in the Liver. PMID: 33446524
Signs and symptoms of the postictal period in epilepsy: A systematic review and meta-analysis. PMID: 30978637
Amentoflavone is a potent broad-spectrum inhibitor of human UDP-glucuronosyltransferases. PMID: 29470958
How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10? PMID: 20089735
Molecular and functional characterization of UDP-glucuronosyltransferase 1A in cynomolgus macaques. PMID: 29944869
Structure- and isoform-specific glucuronidation of six curcumin analogs. PMID: 27324181
Evaluation of human primary intestinal monolayers for drug metabolizing capabilities. PMID: 31709009
[Inhibition of sciadopitysin against UDP-glucuronosyltransferases]. PMID: 29874021
For research use only. Not for human or drug use.
