Conserved motifs in the flavivirus NS3 RNA helicase enzyme. PMID: 34472205
Hepatitis C Virus NS3 Helicase Inhibitor Discovery. PMID: 23762946
The flavivirus NS2B-NS3 protease-helicase as a target for antiviral drug development. PMID: 25842996
Mechanical regulation of the helicase activity of Zika virus NS3. PMID: 35923103
Dengue Virus NS4b N-Terminus Disordered Region Interacts with NS3 Helicase C-Terminal Subdomain to Enhance Helicase Activity. PMID: 36016333
Crystal structure of the NS3 helicase of tick-borne encephalitis virus. PMID: 32505343
Nucleotide-dependent dynamics of the Dengue NS3 helicase. PMID: 32371149
Crystal structure of the NS3-like helicase from Alongshan virus. PMID: 32431821
Functional interplay among the flavivirus NS3 protease, helicase, and cofactors. PMID: 24691778
Flavivirus enzymes and their inhibitors. PMID: 34696835
Zika virus NS3 is a canonical RNA helicase stimulated by NS5 RNA polymerase. PMID: 31361901
Human Norovirus NS3 Has RNA Helicase and Chaperoning Activities. PMID: 29237842
Structure and function of hepatitis C virus NS3 helicase. PMID: 10592661
Novel insights into the function of an N-terminal region of DENV2 NS4B for the optimal helicase activity of NS3. PMID: 33485995
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target. PMID: 17263143
Hepatitis C Virus NS3 Protease and Helicase Inhibitors from Red Sea Sponge (Amphimedon) Species in Green Synthesized Silver Nanoparticles Assisted by in Silico Modeling and Metabolic Profiling. PMID: 32494136
A positively charged surface patch on the pestivirus NS3 protease module plays an important role in modulating NS3 helicase activity and virus production. PMID: 33787991
Molecular docking and simulation of Zika virus NS3 helicase. PMID: 31384814
Ellagic Acid as a Potential Inhibitor against the Nonstructural Protein NS3 Helicase of Zika Virus: A Molecular Modelling Study. PMID: 36046457
Mechanisms of HCV NS3 helicase monitored by optical tweezers. PMID: 25579590
Molecular docking analysis of fluoroquinolones and other natural and synthetic compounds with the HCV NS3 helicase. PMID: 36518146
RNA-Dependent Structures of the RNA-Binding Loop in the Flavivirus NS3 Helicase. PMID: 32105483
Molecular mechanism of ATP and RNA binding to Zika virus NS3 helicase and identification of repurposed drugs using molecular dynamics simulations. PMID: 34516356
The NS3 protease and helicase domains of Japanese encephalitis virus trigger cell death via caspase‑dependent and ‑independent pathways. PMID: 23291778
Targeting the NTPase site of Zika virus NS3 helicase for inhibitor discovery. PMID: 31690231
NS3 helicase domains involved in infectious intracellular hepatitis C virus particle assembly. PMID: 18508894
A Hyperactive Kunjin Virus NS3 Helicase Mutant Demonstrates Increased Dissemination and Mortality in Mosquitoes. PMID: 32699093
Inhibition of hepatitis C virus NS3 helicase by manoalide. PMID: 22394195
Zika virus NS4A N-Terminal region (1-48) acts as a cofactor for inducing NTPase activity of NS3 helicase but not NS3 protease. PMID: 33080173
Recombinant Dengue 2 Virus NS3 Helicase Protein Enhances Antibody and T-Cell Response of Purified Inactivated Vaccine. PMID: 27035715
Suramin inhibits helicase activity of NS3 protein of dengue virus in a fluorescence-based high throughput assay format. PMID: 25281902
Inverse Molecular Docking Study of NS3-Helicase and NS5-RNA Polymerase of Zika Virus as Possible Therapeutic Targets of Ligands Derived from Marcetia taxifolia and Its Implications to Dengue Virus. PMID: 33718704
Effect of protease and helicase mutations on HCV NS3 activity. PMID: 23961124
Ebselen inhibits hepatitis C virus NS3 helicase binding to nucleic acid and prevents viral replication. PMID: 25126694
NS3 helicase from dengue virus specifically recognizes viral RNA sequence to ensure optimal replication. PMID: 29165589
Docking studies of Pakistani HCV NS3 helicase: a possible antiviral drug target. PMID: 25188400
N-Naphthoyl-substituted indole thio-barbituric acid analogs inhibit the helicase activity of the hepatitis C virus NS3. PMID: 30578035
Hepatitis C viral NS3-4A protease activity is enhanced by the NS3 helicase. PMID: 18723512
Psammaplin A inhibits hepatitis C virus NS3 helicase. PMID: 23359228
Structure of the NS3 helicase from Zika virus. PMID: 27399257
Hepatitis C virus NS3 helicase forms oligomeric structures that exhibit optimal DNA unwinding activity in vitro. PMID: 18283103
Uncoupling of Protease trans-Cleavage and Helicase Activities in Pestivirus NS3. PMID: 28835495
Protease Inhibitors (HCV). PMID: 31644194
HCV core antigen plays an important role in the fight against HCV as an alternative to HCV-RNA detection. PMID: 33788295
Cost-effectiveness of chronic hepatitis C screening and treatment. PMID: 34955002
Profile of Roche's cobas® HCV tests. PMID: 28277143
Multicenter performance evaluation of the Elecsys HCV Duo immunoassay. PMID: 36126395
Consensus statement on the management of patients with HCV infection in Romania. PMID: 28331840
Silencing HCV Replication in Its Reservoir. PMID: 30559844
Feasibility of anti-HCV reflex HCV Ag screening strategy in an HCV endemic community. PMID: 33008696
HCV eradication in recurrent hepatitis C after liver transplantation normalizes enhanced endothelial activation. PMID: 34346111
HCV viraemia in anti-HCV-negative haemodialysis patients: Do we need HCV RNA detection test? PMID: 29546809
The correlation of HCV RNA and HCV core antigen in different genotypes of HCV. PMID: 30069909
Comparison of Anti HCV Signal-to-Cutoff Ratio with HCV RNA Results. PMID: 33616333
HCV-specific lymphocyte responses in individuals with positive anti-HCV but negative HCV-RNA. PMID: 25959163
HCV Glycoproteins: Assembly of a Functional E1–E2 Heterodimer. PMID: 21250391
The potential role of HCV core antigen testing in diagnosing HCV infection. PMID: 23322590
Comparison of HCV core antigen and anti-HCV with HCV RNA results. PMID: 25834488
[Application of anti-HCV and HCV RNA detection in intravenous drug users]. PMID: 34107577
HCV false positive immunoassays in patients with LVAD: A potential trap! PMID: 26985592
Animal Models for HCV Study. PMID: 21250390
Transplantation of kidneys from HCV-positive donors: a safe strategy? PMID: 14733406
Hepatitis C viral load in HCV-monoinfected and HCV/HIV-1-, HCV/HTLV-1/-2-, and HCV/HIV/HTLV-1/-2-co-infected patients from São Paulo, Brazil. PMID: 29625021
Comparative evaluation of the Geenius HCV supplemental assay and Inno-LIA HCV score assay in detecting anti-HCV antibodies. PMID: 35728751
Evolving strategy for HCV testing in an Italian tertiary care hospital. PMID: 26921741
Effectiveness of HCV core antigen and RNA quantification in HCV-infected and HCV/HIV-1-coinfected patients. PMID: 25371245
Evaluation of HCV RNA by PCR and Signal-to-Cutoff Ratios of HCV Antibody Assays for Diagnosis of HCV Infection. PMID: 32895701
Effect of antiviral therapy for HCV on lipid levels. PMID: 27685337
Updated Evidence on the Epidemiology of Hepatitis C Virus in Hemodialysis. PMID: 34578181
BODY COMPOSITION CHANGES IN MEN WITH HIV/HCV COINFECTION, HIV MONOINFECTION, AND HCV MONOINFECTION. PMID: 37152870
Vertical transmission of HCV. PMID: 9808375
Hepatitis C core antigen highly correlated to HCV RNA. PMID: 30527202
Comparison of Elecsys Anti-HCV II Assay With Other HCV Screening Assays. PMID: 26667603
HCV virus and lymphoid neoplasms. PMID: 21747860
HCV core antigen is an alternative marker to HCV RNA for evaluating active HCV infection: implications for improved diagnostic option in an era of affordable DAAs. PMID: 29134150
Performance of 6 HCV genotyping 9G test for HCV genotyping in clinical samples. PMID: 29996859
A European multicentre study on the comparison of HCV viral loads between VERIS HCV assay and COBAS® TaqMan® HCV Test and RealTime HCV Assay. PMID: 28319847
Assemble and Interact: Pleiotropic Functions of the HCV Core Protein. PMID: 21250388
HCV antigen testing for the diagnosis of hepatitis C infection: a cost-efficient algorithm. PMID: 24779304
Hepatitis C point-of-care diagnostics: in search of a single visit diagnosis. PMID: 29088981
ML322, A Small Molecule Inhibitor of Dimerization of the Core Protein of Hepatitis C Virus (HCV). PMID: 23833796
Detection of HCV-Specific IFN-γ Responses in HCV Antibody and HCV RNA Negative Injecting Drug Users. PMID: 24497881
[Breastfeeding and hepatitis C virus (HCV): the need for a careful appraisal]. PMID: 11218587
Unsafe Practices Associated with HCV Infection Among Adults: A Case Control Study. PMID: 34447502
HCV screening practices and prevalence in an MCO, 2000-2007. PMID: 21851142
Diagnosis of hepatitis C virus (HCV) infection and laboratory monitoring of its therapy. PMID: 11397664
High HCV treatment uptake in the Swedish HIV/HCV co-infected cohort. PMID: 24984040
Clearance of Hepatitis C Virus (HCV) Is Associated With Improved Outcomes in HCV-Associated Lymphoma. PMID: 33132102
Comparison of HCV viral load and its genotype distributions in HCV mono- and HIV/HCV co-infected illicit drug users. PMID: 28697809
High rate of seronegative HCV infection in HIV-positive patients. PMID: 24649073
Detection of HCV RNA in saliva of patients with hepatitis C virus infection by using a highly sensitive test. PMID: 11849681
Sexual Transmission of HCV in Heterologous Monogamous Spouses. PMID: 26316972
Performance evaluation of the mindray anti-HCV assay for the detection of hepatitis C virus infection. PMID: 30058207
Current characteristics of hemophilia patients co-infected with HIV/HCV in Japan. PMID: 29434818
Hepatitis C (HCV) Viremic Rate and its Correlation to Demographic Factors among HCV Confirmed Iranian Blood Donors. PMID: 30980642
Traceability, reproducibility and clinical evaluation of Sansure Realtime HCV RNA assay. PMID: 26832356
HCV antigen instead of RNA testing to diagnose acute HCV in patients treated in the Dutch Acute HCV in HIV Study. PMID: 28692208
A retrospective study to find the prevalence of HIV, HCV and dual HIV-HCV infection in the prison inmates. PMID: 36618149
[Current approaches for developing new anti-HCV agents and analyses of HCV replication using anti-HCV agents]. PMID: 16308536
Epidemiology of Hepatitis C in Delaware. PMID: 34467133
Implementation of hepatitis C cure in Australia: one year on. PMID: 29682304
HCV antibodies in saliva and urine. PMID: 9580882
Behavioural, not biological, factors drive the HCV epidemic among HIV-positive MSM: HCV and HIV modelling analysis including HCV treatment-as-prevention impact. PMID: 28605503
Performance of ARCHITECT HCV core antigen test with specimens from US plasma donors and injecting drug users. PMID: 25866329
Production and characterization of HCV particles from serum-free culture. PMID: 21550372
Hepatitis C in pregnancy. PMID: 9166361
Hepatitis C virus (HCV) protease variability and anti-HCV protease inhibitor resistance in HIV/HCV-coinfected patients. PMID: 21410862
CpG Island Methylation of Suppressor of Cytokine Signaling-1 Gene Induced by HCV Is Associated With HCV-Related Hepatocellular Carcinoma. PMID: 35733955
High prevalence of unawareness of HCV infection status among both HCV-seronegative and seropositive people living with human immunodeficiency virus in Taiwan. PMID: 33956867
Hepatitis B Virus X Protein Stimulates Hepatitis C Virus (HCV) Replication by Protecting HCV Core Protein from E6AP-Mediated Proteasomal Degradation. PMID: 36374094
Liver Retransplantation for Recurrence of HCV-Related Cirrhosis Using Hepatitis C-Positive Allografts: A 19-Year OPTN Analysis. PMID: 27137953
Evaluation of a new point-of-care oral anti-HCV test for screening of hepatitis C virus infection. PMID: 32005264
Distribution of hepatitis C virus (HCV) genotypes in a Saudi Arabian hospital during the 2015-2020 period. PMID: 35146350
Acute hepatitis C virus infection: clinical update and remaining challenges. PMID: 36800699
For research use only. Not for human or drug use.
