Catalog No.
RVV08904
Host species
Mouse
Species reactivity
Human papillomavirus type 16
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Concentration
1 mg/ml
Purity
>95% by SDS-PAGE.
Clonality
Monoclonal
Isotype
VHH-mFC
Applications
ELISA,Neut,WB
Target
E7/Protein E7
Purification
Protein A or G purified from cell culture supernatant.
Endotoxin level
Please contact with the lab for this information.
Expression system
XtenCHO
Accession
P03129
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.Store at +4°C short term (1-2 weeks).Store at -20 °C 12 months. Store at -80°C long term.
Alternative Names
E7, Protein E7, Human Papillomavirus (HPV)
Note
For research use only.
B7-H3 in tumors: friend or foe for tumor immunity? PMID: 29299639
The role of alpha 6 beta 1 integrin and EGF in normal and malignant acinar morphogenesis of human prostatic epithelial cells. PMID: 11506815
Evaluating bulk Nb2O2F3 for Li-battery electrode applications. PMID: 26751421
HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING. PMID: 31874109
Murine HPV16 E7-expressing transgenic skin effectively emulates the cellular and molecular features of human high-grade squamous intraepithelial lesions. PMID: 29807614
HPV16 AND EXPRESSION OF PROTEIN P16INK4A AND E7 ONCOPROTEIN IN COLORECTAL CARCINOMA. PMID: 35107499
Development of a Spontaneous HPV16 E6/E7-Expressing Head and Neck Squamous Cell Carcinoma in HLA-A2 Transgenic Mice. PMID: 35089069
Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens. PMID: 33335126
Local radiotherapy and E7 RNA-LPX vaccination show enhanced therapeutic efficacy in preclinical models of HPV16+ cancer. PMID: 34971406
HPV16 E6 and E7 Oncoproteins Stimulate the Glutamine Pathway Maintaining Cell Proliferation in a SNAT1-Dependent Fashion. PMID: 36851539
The HPV16 E6, E7/miR-23b-3p/ICAT signaling axis promotes proliferation, migration, invasion and EMT of cervical cancer cells. PMID: 36847693
Modeling and Molecular Dynamics of the 3D Structure of the HPV16 E7 Protein and Its Variants. PMID: 33573298
HPV16 E6/E7 upregulates HIF-2α and VEGF by inhibiting LKB1 in lung cancer cells. PMID: 28720067
HPV 16 E7 alters translesion synthesis signaling. PMID: 36266721
A novel function of HPV16-E6/E7 in epithelial-mesenchymal transition. PMID: 23628416
The expression of Oct3/4A mRNA and not its isoforms is upregulated by the HPV16 E7 oncoprotein. PMID: 36378419
Immunization of mice by the co-administration of codon-optimized HPV16 E7 and lL12 genes against HPV16-associated cervical cancer. PMID: 31004722
The Intracellular Delivery Of Anti-HPV16 E7 scFvs Through Engineered Extracellular Vesicles Inhibits The Proliferation Of HPV-Infected Cells. PMID: 31806970
HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis. PMID: 25439690
Significant growth inhibition by a bispecific affibody targeting oncoprotein E7 in both HPV16 and 18 positive cervical cancer in vitro and in vivo. PMID: 35245683
Association of cervical carcinogenesis risk with HPV16 E6 and E7 variants in the Taizhou area, China. PMID: 34217247
Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system. PMID: 28786561
HPV16 oncogenes E6 or/and E7 may influence the methylation status of RASSFIA gene promoter region in cervical cancer cell line HT-3. PMID: 28260046
Epithelium Expressing the E7 Oncoprotein of HPV16 Attracts Immune-Modulatory Dendritic Cells to the Skin and Suppresses Their Antigen-Processing Capacity. PMID: 27031095
CUL2 overexpression driven by CUL2/E2F1/miR-424 regulatory loop promotes HPV16 E7 induced cervical carcinogenesis. PMID: 27153550
HnRNP D activates production of HPV16 E1 and E6 mRNAs by promoting intron retention. PMID: 35234917
Apoptosis induced by an antagonist peptide against HPV16 E7 in vitro and in vivo via restoration of p53. PMID: 21475994
Non-Metabolic Functions of PKM2 Contribute to Cervical Cancer Cell Proliferation Induced by the HPV16 E7 Oncoprotein. PMID: 33800513
Distinctive distribution of HPV16 E6 D25E and E7 N29S intratypic Asian variants in Korean commercial sex workers. PMID: 17311337
Molecular and evolutionary analysis of HPV16 E6 and E7 genes in Greek women. PMID: 23946477
HPV16 E7 DNA tattooing: safety, immunogenicity, and clinical response in patients with HPV-positive vulvar intraepithelial neoplasia. PMID: 28451790
hnRNP G/RBMX enhances HPV16 E2 mRNA splicing through a novel splicing enhancer and inhibits production of spliced E7 oncogene mRNAs. PMID: 35357488
Detection of Circulating HPV16 DNA as a Biomarker for Cervical Cancer by a Bead-Based HPV Genotyping Assay. PMID: 35225653
Systematic Analysis of IL-1 Cytokine Signaling Suppression by HPV16 Oncoproteins. PMID: 36342298
Frequent presence of incomplete HPV16 E7 ORFs in lung carcinomas: memories of viral infection. PMID: 20850378
HPV16-transformed human keratinocytes depend on SIX1 expression for proliferation and HPV E6/E7 gene expression. PMID: 31425971
HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytes. PMID: 23592995
Disruption of HPV16-E7 by CRISPR/Cas system induces apoptosis and growth inhibition in HPV16 positive human cervical cancer cells. PMID: 25136604
The heterogeneous structural behavior of E7 from HPV16 revealed by NMR spectroscopy. PMID: 23940009
Human Papillomavirus 16 E6 and E7 Synergistically Repress Innate Immune Gene Transcription. PMID: 31915229
Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway. PMID: 30410307
For research use only. Not for human or drug use.
