Catalog No.
RVV08903
Expression system
Mammalian Cells
Species reactivity
Human papillomavirus type 16
Host species
Mouse
Isotype
VHH-mFC
Clonality
Monoclonal
Target
E7, Protein E7
Concentration
3.97 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03129
Applications
ELISA, Neutralization, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Nb4
Selection and identification of an ssDNA aptamer to NB4 cell. PMID: 33522630
Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes. PMID: 11704857
Role of cofilin‑1 in arsenic trioxide‑induced apoptosis of NB4‑R1 cells. PMID: 33174611
KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2. PMID: 34448811
[Effects of Monoammonium Glycyrrhizinate on Stem Cell-like Characteristics, Oxidative Stress and Mitochondrial Function of Acute Promyelocytic Leukemia NB4 Cells]. PMID: 35123599
Degradation and defluorination of 6:2 fluorotelomer sulfonamidoalkyl betaine and 6:2 fluorotelomer sulfonate by Gordonia sp. strain NB4-1Y under sulfur-limiting conditions. PMID: 30092525
Effects of LG268 on Cell Proliferation and Apoptosis of NB4 Cells. PMID: 27429588
Autophagy and apoptosis induction by sesamin in MOLT-4 and NB4 leukemia cells. PMID: 33262824
[Effect of PADI4 on the Expression of Inflammatory Cytokines During NB4 Cells Differentiation]. PMID: 34362483
Tanshinone IIa Induces Autophagy and Apoptosis via PI3K/Akt/mTOR Axis in Acute Promyelocytic Leukemia NB4 Cells. PMID: 34691211
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades. PMID: 33841010
[Role of Reactive Oxygen Species in GDC-0152-Induced Apoptosis and Autophagy of NB4 cells]. PMID: 31839039
Upregulation of Metallothionein-1G Accelerates G1/S Transition in the Growth Phase of Acute Promyelocytic Leukemia NB4 Cells. PMID: 33653779
Zinc Depletion by TPEN Induces Apoptosis in Human Acute Promyelocytic NB4 Cells. PMID: 28750402
NB4 cells show bilineage potential and an aberrant pattern of neutrophil secondary granule protein gene expression. PMID: 7517212
The in vitro study of apoptosis in NB4 cell induced by citral. PMID: 22573288
[Effects of decitabine on proliferation and apoptosis of NB4 and K562 cells]. PMID: 23628032
Interferon-γ enhances promyelocytic leukemia protein expression in acute promyelocytic cells and cooperates with all-trans-retinoic acid to induce maturation of NB4 and NB4-R1 cells. PMID: 22969967
PML-RARα stabilized by zinc in human acute promyelocytic leukemia NB4 cells. PMID: 28743050
Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells. PMID: 28890200
RIG-G inhibits the proliferation of NB4 cells and propels ATRA-induced differentiation of APL cells. PMID: 26686474
Chloroquine exerts antitumor effects on NB4 acute promyelocytic leukemia cells and functions synergistically with arsenic trioxide. PMID: 29434902
Gene expression profiling of NB4 cells following knockdown of nucleostemin using DNA microarrays. PMID: 27374947
[Mechanism of apoptosis in human leukemia NB4 cells induced by total astragalosides]. PMID: 21875462
Characterization of arsenic-induced cytogenetic alterations in acute promyelocytic leukemia cell line, NB4. PMID: 21544632
Effects of lapatinib on cell proliferation and apoptosis in NB4 cells. PMID: 29387217
Down-regulating the expression of IL-3Rβ interfered with the proliferation, not differentiation in NB4 cells. PMID: 21207215
2-NDC from dithiocarbamates improves ATRA efficiency and ROS-induced apoptosis via downregulation of Bcl2 and Survivin in human acute promyelocytic NB4 cells. PMID: 32096428
Retinoic acid induces adhesion and migration in NB4 cells through Pyk2 signaling. PMID: 23587524
Verteporfin Inhibits Cell Proliferation and Induces Apoptosis in Human Leukemia NB4 Cells without Light Activation. PMID: 28924376
Roles of PADI4 in the expression of cytokines involved in inflammation and adhesion in differentiated NB4 cells treated with ATRA. PMID: 36815967
Human acute promyelocytic leukemia NB4 cells are sensitive to esculetin through induction of an apoptotic mechanism. PMID: 24995577
Antileukaemia immunity: effect of exosomes against NB4 acute promyelocytic leukaemia cells. PMID: 21819704
Zoledronic acid exerts antitumor effects in NB4 acute promyelocytic leukemia cells by inducing apoptosis and S phase arrest. PMID: 25312823
Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells. PMID: 22981223
[Mechanisms of sorafenib induced NB4 cell apoptosis]. PMID: 25687050
Selective induction of apoptosis of NB4 cells from G2+M phase by sodium arsenite at lower doses. PMID: 9688289
Retinoic acid resistance in NB4 APL cells is associated with lack of interferon alpha synthesis Stat1 and p48 induction. PMID: 10435617
Inhibition of Cyclin-dependent Kinase (CDK) Decreased Survival of NB4 Leukemic Cells: Proposing a p53-Independent Sensitivity of Leukemic Cells to Multi-CDKs Inhibitor AT7519. PMID: 33680018
[NB4 cell apoptosis induced by bortezomib combined with As(2)O(3) and its mechanism]. PMID: 21518486
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia. PMID: 35013142
Establishment of two-dimensional gel electrophoresis profiles of the human acute promyelocytic leukemia cell line NB4. PMID: 22736039
Esculetin Neutralises Cytotoxicity of t-BHP but Not of H2O2 on Human Leukaemia NB4 Cells. PMID: 28367450
[In vitro effect of lovastatin on NB4 promyelocytic leukemia cells]. PMID: 11855147
For research use only. Not for human or drug use.
