Selection and identification of an ssDNA aptamer to NB4 cell. PMID: 33522630
Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes. PMID: 11704857
Role of cofilin‑1 in arsenic trioxide‑induced apoptosis of NB4‑R1 cells. PMID: 33174611
KDM5A suppresses PML-RARα target gene expression and APL differentiation through repressing H3K4me2. PMID: 34448811
[Effects of Monoammonium Glycyrrhizinate on Stem Cell-like Characteristics, Oxidative Stress and Mitochondrial Function of Acute Promyelocytic Leukemia NB4 Cells]. PMID: 35123599
Degradation and defluorination of 6:2 fluorotelomer sulfonamidoalkyl betaine and 6:2 fluorotelomer sulfonate by Gordonia sp. strain NB4-1Y under sulfur-limiting conditions. PMID: 30092525
Effects of LG268 on Cell Proliferation and Apoptosis of NB4 Cells. PMID: 27429588
Autophagy and apoptosis induction by sesamin in MOLT-4 and NB4 leukemia cells. PMID: 33262824
[Effect of PADI4 on the Expression of Inflammatory Cytokines During NB4 Cells Differentiation]. PMID: 34362483
Tanshinone IIa Induces Autophagy and Apoptosis via PI3K/Akt/mTOR Axis in Acute Promyelocytic Leukemia NB4 Cells. PMID: 34691211
20(S)-ginsenoside Rh2 induces caspase-dependent promyelocytic leukemia-retinoic acid receptor A degradation in NB4 cells via Akt/Bax/caspase9 and TNF-α/caspase8 signaling cascades. PMID: 33841010
[Role of Reactive Oxygen Species in GDC-0152-Induced Apoptosis and Autophagy of NB4 cells]. PMID: 31839039
Upregulation of Metallothionein-1G Accelerates G1/S Transition in the Growth Phase of Acute Promyelocytic Leukemia NB4 Cells. PMID: 33653779
Zinc Depletion by TPEN Induces Apoptosis in Human Acute Promyelocytic NB4 Cells. PMID: 28750402
NB4 cells show bilineage potential and an aberrant pattern of neutrophil secondary granule protein gene expression. PMID: 7517212
The in vitro study of apoptosis in NB4 cell induced by citral. PMID: 22573288
[Effects of decitabine on proliferation and apoptosis of NB4 and K562 cells]. PMID: 23628032
Interferon-γ enhances promyelocytic leukemia protein expression in acute promyelocytic cells and cooperates with all-trans-retinoic acid to induce maturation of NB4 and NB4-R1 cells. PMID: 22969967
PML-RARα stabilized by zinc in human acute promyelocytic leukemia NB4 cells. PMID: 28743050
Esculetin modulates cytotoxicity induced by oxidants in NB4 human leukemia cells. PMID: 28890200
RIG-G inhibits the proliferation of NB4 cells and propels ATRA-induced differentiation of APL cells. PMID: 26686474
Chloroquine exerts antitumor effects on NB4 acute promyelocytic leukemia cells and functions synergistically with arsenic trioxide. PMID: 29434902
Gene expression profiling of NB4 cells following knockdown of nucleostemin using DNA microarrays. PMID: 27374947
[Mechanism of apoptosis in human leukemia NB4 cells induced by total astragalosides]. PMID: 21875462
Characterization of arsenic-induced cytogenetic alterations in acute promyelocytic leukemia cell line, NB4. PMID: 21544632
Effects of lapatinib on cell proliferation and apoptosis in NB4 cells. PMID: 29387217
Down-regulating the expression of IL-3Rβ interfered with the proliferation, not differentiation in NB4 cells. PMID: 21207215
2-NDC from dithiocarbamates improves ATRA efficiency and ROS-induced apoptosis via downregulation of Bcl2 and Survivin in human acute promyelocytic NB4 cells. PMID: 32096428
Retinoic acid induces adhesion and migration in NB4 cells through Pyk2 signaling. PMID: 23587524
Verteporfin Inhibits Cell Proliferation and Induces Apoptosis in Human Leukemia NB4 Cells without Light Activation. PMID: 28924376
Roles of PADI4 in the expression of cytokines involved in inflammation and adhesion in differentiated NB4 cells treated with ATRA. PMID: 36815967
Human acute promyelocytic leukemia NB4 cells are sensitive to esculetin through induction of an apoptotic mechanism. PMID: 24995577
Antileukaemia immunity: effect of exosomes against NB4 acute promyelocytic leukaemia cells. PMID: 21819704
Zoledronic acid exerts antitumor effects in NB4 acute promyelocytic leukemia cells by inducing apoptosis and S phase arrest. PMID: 25312823
Inhibition of damage-regulated autophagy modulator-1 (DRAM-1) impairs neutrophil differentiation of NB4 APL cells. PMID: 22981223
[Mechanisms of sorafenib induced NB4 cell apoptosis]. PMID: 25687050
Selective induction of apoptosis of NB4 cells from G2+M phase by sodium arsenite at lower doses. PMID: 9688289
Retinoic acid resistance in NB4 APL cells is associated with lack of interferon alpha synthesis Stat1 and p48 induction. PMID: 10435617
Inhibition of Cyclin-dependent Kinase (CDK) Decreased Survival of NB4 Leukemic Cells: Proposing a p53-Independent Sensitivity of Leukemic Cells to Multi-CDKs Inhibitor AT7519. PMID: 33680018
[NB4 cell apoptosis induced by bortezomib combined with As(2)O(3) and its mechanism]. PMID: 21518486
Role of cardiolipins, mitochondria, and autophagy in the differentiation process activated by all-trans retinoic acid in acute promyelocytic leukemia. PMID: 35013142
Establishment of two-dimensional gel electrophoresis profiles of the human acute promyelocytic leukemia cell line NB4. PMID: 22736039
Esculetin Neutralises Cytotoxicity of t-BHP but Not of H2O2 on Human Leukaemia NB4 Cells. PMID: 28367450
[In vitro effect of lovastatin on NB4 promyelocytic leukemia cells]. PMID: 11855147
A Luminescence-Based Method for In Vitro Screening of Immunomodulatory Checkpoints and Therapeutics., PMID:40402459
Immunization with recombinant HPV16-E7d in fusion with Flagellin as a cancer vaccine: Effect of antigen-adjuvant orientation on the immune response pattern., PMID:39939497
Development and evaluation of a novel E7 multi-epitopic vaccine for human papillomavirus type 16: design, expression, purification, and immunological characterization., PMID:39910471
HPV16 mutant E6/E7 construct is protective in mouse model., PMID:39350162
MAL expression downregulation through suppressive H3K27me3 marks at the promoter in HPV16-related cervical cancers is prognostically relevant and manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2., PMID:38461243
Evaluation of HPV 16 and HPV 18 Oncoprotein Expression as Alternative Diagnostic Tools in Cervical Lesion., PMID:38415538
A Therapeutic DNA Vaccine Targeting HPV16 E7 in Combination with Anti-PD-1/PD-L1 Enhanced Tumor Regression and Cytotoxic Immune Responses., PMID:37895145
Skin-Grafting and Dendritic Cell "Boosted" Humanized Mouse Models Allow the Pre-Clinical Evaluation of Therapeutic Cancer Vaccines., PMID:37626903
A luminescence-based method to assess antigen presentation and antigen-specific T cell responses for in vitro screening of immunomodulatory checkpoints and therapeutics., PMID:37559730
HPV types 16/18 L1 E6 and E7 proteins seropositivity and cervical cancer risk in HIV-positive and HIV-negative black South African women., PMID:35351184
Immunohistochemical Detection of Human Papillomavirus 16 E7 Oncoprotein in Cervical Lesions., PMID:34729114
Targeting Human Papillomavirus-Associated Cancer by Oncoprotein-Specific Recombinant Antibodies., PMID:34502053
Potent, Selective CARs as Potential T-Cell Therapeutics for HPV-positive Cancers., PMID:34432728
Antigen Delivery to DEC205+ Dendritic Cells Induces Immunological Memory and Protective Therapeutic Effects against HPV-Associated Tumors at Different Anatomical Sites., PMID:34345218
Serum HPV16 E7 Oncoprotein Is a Recurrence Marker of Oropharyngeal Squamous Cell Carcinomas., PMID:34282779
Enhancing immunogenicity of HPV16 E7 DNA vaccine by conjugating codon-optimized GM-CSF to HPV16 E7 DNA., PMID:34247810
Investigating the association between serum human papillomavirus type 16 E7 antibodies and risk of head and neck cancer., PMID:33949155
ePCL Electrospun Microfibrous Layers for Immune Assays: Sensitive ELISA for the Detection of Serum Antibodies Against HPV16 E7 Oncoprotein., PMID:33842749
Combination of a T cell activating therapy and anti-phosphatidylserine enhances anti-tumour immune responses in a HPV16 E7-expressing C3 tumour model., PMID:33627686
Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors., PMID:33485370
Development of DNA Vaccine Targeting E6 and E7 Proteins of Human Papillomavirus 16 (HPV16) and HPV18 for Immunotherapy in Combination with Recombinant Vaccinia Boost and PD-1 Antibody., PMID:33468698
Evaluation of HPV16 E7 expression in head and neck carcinoma cell lines and clinical specimens., PMID:33335126
PD-1 blockade synergizes with intratumoral vaccination of a therapeutic HPV protein vaccine and elicits regression of tumor in a preclinical model., PMID:33108473
A phase 1, single centre, open label, escalating dose study to assess the safety, tolerability and immunogenicity of a therapeutic human papillomavirus (HPV) DNA vaccine (AMV002) for HPV-associated head and neck cancer (HNC)., PMID:32918586
Epitope Mapping and Computational Analysis of Anti-HPV16 E6 and E7 Antibodies in Single-Chain Format for Clinical Development as Antitumor Drugs., PMID:32640530
A preliminary study on the immune responses of HPV16-E7 by combined intranasal immunization with lymphotoxin., PMID:32627150
Immunomodulation to enhance the efficacy of an HPV therapeutic vaccine., PMID:32554612
Development and validation of a multiplex immunoassay for the simultaneous quantification of type-specific IgG antibodies to E6/E7 oncoproteins of HPV16 and HPV18., PMID:32214362
Preparation, Characterization and Diagnostic Valuation of Two Novel Anti-HPV16 E7 Oncoprotein Monoclonal Antibodies., PMID:32204370
Antibodies against human papillomavirus proteins in Barrett's dysplasia and intramucosal esophageal adenocarcinoma., PMID:32170783
A Phase 1 Trial Assessing the Safety and Tolerability of a Therapeutic DNA Vaccination Against HPV16 and HPV18 E6/E7 Oncogenes After Chemoradiation for Cervical Cancer., PMID:32151670
Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment., PMID:32111835
CUE-101, a Novel E7-pHLA-IL2-Fc Fusion Protein, Enhances Tumor Antigen-Specific T-Cell Activation for the Treatment of HPV16-Driven Malignancies., PMID:31964784
FLT3L and granulocyte macrophage colony-stimulating factor enhance the anti-tumor and immune effects of an HPV16 E6/E7 vaccine., PMID:31881013
The Intracellular Delivery Of Anti-HPV16 E7 scFvs Through Engineered Extracellular Vesicles Inhibits The Proliferation Of HPV-Infected Cells., PMID:31806970
TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures., PMID:31745340
A phase 1/2a, dose-escalation, safety and preliminary efficacy study of oral therapeutic vaccine in subjects with cervical intraepithelial neoplasia 3., PMID:31576684
Prognostic value of posttreatment HPV-specific antibodies in patients with oropharyngeal tumors., PMID:30986340
Post-treatment human papillomavirus antibody kinetics in cervical cancer patients., PMID:30955486
Nanobody against the E7 oncoprotein of human papillomavirus 16., PMID:30849663
Significance of serum antibodies against HPV E7, Hsp27, Hsp20 and Hp91 in Iranian HPV-exposed women., PMID:30755156
Extracellular overproduction of E7 oncoprotein of Iranian human papillomavirus type 16 by genetically engineered Lactococcus lactis., PMID:30678667
Increased Response of Human T-Lymphocytes by Dendritic Cells Pulsed with HPV16E7 and Pleurotus sajor-caju-β-glucan (PBG)., PMID:30593739
Nuclear lactate dehydrogenase A senses ROS to produce α-hydroxybutyrate for HPV-induced cervical tumor growth., PMID:30356100
Profiling of serum antibodies against human papillomavirus antigens in Korean women with cervical intraepithelial neoplasia and cervical cancer., PMID:30353680
Oral immunization with recombinant Lactococcus lactis NZ9000 expressing human papillomavirus type 16 E7 antigen and evaluation of its immune effects in female C57BL/6 mice., PMID:30192395
Small Heat Shock Proteins B1 and B6: Which One is the Most Effective Adjuvant in Therapeutic HPV Vaccine?, PMID:30171788
Nanoparticle Conjugation of Human Papillomavirus 16 E7-long Peptides Enhances Therapeutic Vaccine Efficacy against Solid Tumors in Mice., PMID:30131378
Mucosal HPV E6/E7 Peptide Vaccination in Combination with Immune Checkpoint Modulation Induces Regression of HPV+ Oral Cancers., PMID:30054333
A novel HPV16 E7-affitoxin for targeted therapy of HPV16-induced human cervical cancer., PMID:30026865
For research use only. Not for human or drug use.
