Catalog No.
RVV08805
Expression system
Mammalian Cells
Species reactivity
Human papillomavirus type 16
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Target
L1, Major capsid protein L1
Concentration
1.93 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P03101
Applications
ELISA, Neutralization, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
H16.V5
A cryo-electron microscopy study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment. PMID: 25392224
A human monoclonal antibody against HPV16 recognizes an immunodominant and neutralizing epitope partially overlapping with that of H16.V5. PMID: 26750243
High-Resolution Structure Analysis of Antibody V5 and U4 Conformational Epitopes on Human Papillomavirus 16. PMID: 29211035
Characterization of a major neutralizing epitope on human papillomavirus type 16 L1. PMID: 10233949
Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity. PMID: 22356831
Characterization of a human papillomavirus type 16 variant-dependent neutralizing epitope. PMID: 9223527
Antibody Competition Reveals Surface Location of HPV L2 Minor Capsid Protein Residues 17-36. PMID: 29125554
Mapping of human serum-reactive epitopes in virus-like particles of human papillomavirus types 16 and 11. PMID: 12832218
Development of a non-denaturing electrophoresis system for characterization of neutralizing epitopes on HPV virus-like particles. PMID: 17137641
Quantitation and biospecific identification of virus-like particles of human papillomavirus by capillary electrophoresis. PMID: 28841998
Characterization of virus-like particles in GARDASIL® by cryo transmission electron microscopy. PMID: 24299977
A deletion and point mutation study of the human papillomavirus type 16 major capsid gene. PMID: 16938363
The choice of resin-bound ligand affects the structure and immunogenicity of column-purified human papillomavirus type 16 virus-like particles. PMID: 22563414
Deletion of a major neutralizing epitope of human papillomavirus type 16 virus-like particles. PMID: 17325351
Type-specific and cross-reactive antibodies induced by human papillomavirus 31 L1/L2 virus-like particles. PMID: 17577054
Development and Characterization of an HPV Type-16 Specific Modified DNA Aptamer for the Improvement of Potency Assays. PMID: 28233502
Transient expression of Human papillomavirus type 16 L1 protein in Nicotiana benthamiana using an infectious tobamovirus vector. PMID: 16530873
Production of human papillomavirus type 16 L1 virus-like particles by recombinant Lactobacillus casei cells. PMID: 16391114
Identification of a human papillomavirus type 16-specific epitope on the C-terminal arm of the major capsid protein L1. PMID: 14557648
Immunization with Human Papillomavirus 16 L1+E2 Chimeric Capsomers Elicits Cellular Immune Response and Antitumor Activity in a Mouse Model. PMID: 27058179
Correlation between mouse potency and in vitro relative potency for human papillomavirus Type 16 virus-like particles and Gardasil vaccine samples. PMID: 17012876
Evolution of type-specific immunoassays to evaluate the functional immune response to Gardasil: a vaccine for human papillomavirus types 16, 18, 6 and 11. PMID: 18388490
Hybrid papillomavirus L1 molecules assemble into virus-like particles that reconstitute conformational epitopes and induce neutralizing antibodies to distinct HPV types. PMID: 11878901
Chimeric human papillomavirus type 16 (HPV-16) L1 particles presenting the common neutralizing epitope for the L2 minor capsid protein of HPV-6 and HPV-16. PMID: 12857908
Expression of Human papillomavirus type 16 major capsid protein in transgenic Nicotiana tabacum cv. Xanthi. PMID: 14505089
For research use only. Not for human or drug use.
