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Anti-Human IL33 Antibody (C2_2E12)

Catalog #:   RHB74001 Specific References (101) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: Blocking, ELISA, WB
Accession: O95760
Overview

Catalog No.

RHB74001

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Target

NF-HEV, IL-1F11, C9orf26, IL-33, Interleukin-1 family member 11, IL33, Nuclear factor from high endothelial venules, NFHEV, Interleukin-33, IL1F11

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O95760

Applications

Blocking, ELISA, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

C2_2E12

Data Image
References

HMGB1, IL-1alpha, IL-33 and S100 proteins: dual-function alarmins. PMID: 27569562

Contributions of IL-33 in Non-hematopoietic Lung Cells to Obstructive Lung Disease. PMID: 32903501

Targeting IL-33/ST2 signaling: regulation of immune function and analgesia. PMID: 29076792

Prospects for Monoclonal Antibody Therapy in Pediatric Asthma. PMID: 29992472

Emerging Roles of Interleukin-33-responsive Kidney Group 2 Innate Lymphoid Cells in Acute Kidney Injury. PMID: 32102434

Interleukin 33 is a guardian of barriers and a local alarmin. PMID: 26784265

The IL-33/ST2 pathway, inflammation and atherosclerosis: Trigger and target? PMID: 29793758

IL-33/ST2 Pathway as a Rational Therapeutic Target for CNS Diseases. PMID: 29175156

Genetic Association of Interleukin 33/ST2 Polymorphisms With Behcet's Uveitis. PMID: 33859633

IL-33: a key player in the development of iron-recycling red pulp macrophages. PMID: 32737432

Regulatory T cell is critical for interleukin-33-mediated neuroprotection against stroke. PMID: 32044328

Interleukin-33 in tumorigenesis, tumor immune evasion, and cancer immunotherapy. PMID: 26922618

IL-33 is associated with allergy in children sensitized to the cat. PMID: 31477395

Linking VEGF Deficiency and IL-33 Upregulation in Chronic Obstructive Pulmonary Disease. PMID: 31100009

Neuroprotective effect of astrocyte-derived IL-33 in neonatal hypoxic-ischemic brain injury. PMID: 32859229

[Changes of serum interleukin-33 in preterm infants with bronchopulmonary dysplasia]. PMID: 32669167

IL-33 Mediates Lung Inflammation by the IL-6-Type Cytokine Oncostatin M. PMID: 33376451

Cloning and functional testing of rhesus macaque (Macaca mulatta) IL-9 and IL-33. PMID: 32017131

The curious case of IL-33 in homeostasis and infection. PMID: 33222176

Role of IL-33/ST2 signaling pathway in systemic sclerosis and other fibrotic diseases. PMID: 31498062

IL-33 Exacerbates Endometriotic Lesions via Polarizing Peritoneal Macrophages to M2 Subtype. PMID: 32046466

IL-33 Changes Our "Gut Feelings" about Serotonin. PMID: 33440138

[The role of interleukin 33 in bronchial asthma and its current research status]. PMID: 32164096

A Truncated Form of HpARI Stabilizes IL-33, Amplifying Responses to the Cytokine. PMID: 32695116

Lack of interleukin-33 and its receptor does not prevent calcipotriol-induced atopic dermatitis-like inflammation in mice. PMID: 32296080

Behavioral Changes in Mice Lacking Interleukin-33. PMID: 29379874

IL-33 Deals with the Gray Matter. PMID: 29562200

IL-33 meets allergens at the gate. PMID: 29563627

Exogenous interleukin-33 promotes hepatocellular carcinoma growth by remodelling the tumour microenvironment. PMID: 33308251

IL-33/ST2 signaling modulates Afghanistan particulate matter induced airway hyperresponsiveness in mice. PMID: 32777237

Interleukin (IL)-33 and the IL-1 Family of Cytokines-Regulators of Inflammation and Tissue Homeostasis. PMID: 29101106

Allergy: Neonatal IL-33 drives allergy. PMID: 28044058

Nociceptor Interleukin 33 Receptor/ST2 Signaling in Vibration-Induced Muscle Pain in the Rat. PMID: 31562993

Pathophysiologic role of Interleukin-33/ST2 in Sjogren's syndrome. PMID: 33476812

Clinical Value of Serum Interleukin-33 Biomarker in Infants With Neonatal Cholestasis. PMID: 31764415

Interleukin-33 delays recovery of mucosal inflammation via downregulation of homeostatic ABCG5/8 in the colon. PMID: 31641224

Characterization of immune responses and the lung transcriptome in a murine model of IL-33 challenge. PMID: 32841733

The Ca(2+)-dependent pathway contributes to changes in the subcellular localization and extracellular release of interleukin-33. PMID: 32768188

Early Treatment of Interleukin-33 can Attenuate Lupus Development in Young NZB/W F1 Mice. PMID: 33182616

The enigmatic processing and secretion of interleukin-33. PMID: 20305685

ST2 and the ST2/IL-33 signalling pathway-biochemistry and pathophysiology in animal models and humans. PMID: 31136737

Pleiotropic Effects of IL-33 on CD4(+) T Cell Differentiation and Effector Functions. PMID: 30949175

Function of IL-33 in Wound Age Estimation of Skin Wounds in Mice. PMID: 32530166

Epithelium-derived IL-33 activates mast cells to initiate neutrophil recruitment following corneal injury. PMID: 32615259

Robust production of IL-33 and TSLP by lung endothelial cells in response to low-dose dsRNA stimulation. PMID: 32360270

The Pleiotropic Immunomodulatory Functions of IL-33 and Its Implications in Tumor Immunity. PMID: 30483263

Dichotomous function of IL-33 in health and disease: From biology to clinical implications. PMID: 29309756

Elevated expression of interleukin-33 in myasthenia gravis patients. PMID: 30827881

[Murine asthma model focusing on IL-33]. PMID: 28794302

Dynamic Expression of Interleukin-33 and ST2 in the Mouse Reproductive Tract Is Influenced by Superovulation. PMID: 32108542

Blocking of the IL-33/ST2 Signaling Axis by a Single-Chain Antibody Variable Fragment (scFv) Specific to IL-33 with a Defined Epitope. PMID: 32971846

IL-33 Has a Protective Effect Against Perinatal Listeriosis by Regulating Mitophagy of CD8+ T Lymphocytes., PMID:40512525

Topical delivery of a human single-domain antibody targeting IL-33 to inhibit mucosal inflammation., PMID:40500403

Targeting IL-33 to Suppress Ferroptosis and Alleviate Inflammation in Asthma Exacerbations., PMID:40499633

Polynucleotides Enhance Skin Barrier Function and Reduce Inflammation in a 2,4-Dinitrochlorobenzene-Induced Mouse Model of Atopic Dermatitis., PMID:40484710

Mechanistic insights into ozone-induced asthma exacerbation: role of oxidative stress and IL-33., PMID:40446373

Enhancing the Affinity of a Novel Selective scFv for Soluble ST2 through Computational Design., PMID:40417773

Interleukin 33 Promotes Liver Sinusoidal Endothelial Cell Dysfunction and Hepatic Fibrosis in Diabetic Mice., PMID:40403761

Vaccination against helminth IL-33 modulators permits immune-mediated parasite ejection., PMID:40378045

IL1RAP Expression in Human Atherosclerosis: A Target of Novel Antibodies to Reduce Vascular Inflammation and Adhesion., PMID:40371594

Microneedles Coated with Cow's Milk Proteins: Immunogenicity, Stability, and Safety Assessment., PMID:40366634

Pro-inflammatory cytokines in myasthenia gravis: a systematic review and meta-analysis., PMID:40347402

Anti-ST2 antibody reduces airway hyperresponsiveness mediated by monocyte-derived macrophages during influenza A infection., PMID:40319941

Sensitization Potential of the Major Soybean Allergen Gly m 4 and Its Cross-Reactivity with the Birch Pollen Allergen Bet v 1., PMID:40243572

Molecular and Immunometabolic Landscape of Erythrophagocytosis-induced Ferroptosis., PMID:40231500

IgE-Mediated Activation of Mast Cells and Basophils in Health and Disease., PMID:40165512

A phase 2a trial of the IL-33 mAb tozorakimab in patients with COPD: FRONTIER-4., PMID:40154559

Development of a point-of-care test for the simultaneous detection of respiratory syncytial virus and IL-33 as a disease biomarker in children., PMID:40148664

IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro., PMID:40118005

Maintenance of graft tissue-resident Foxp3+ cells is necessary for lung transplant tolerance in mice., PMID:40100295

IL-33-Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1-IGF2R Axis in Ankylosing Spondylitis., PMID:40091508

Neutralization of acyl CoA binding protein (ACBP) for the experimental treatment of osteoarthritis., PMID:40082721

Protease-activated receptor 2 and interleukin-13 receptor α1 activation is linked to eosinophilic chronic rhinosinusitis., PMID:40074076

Maternal supplementation with α-tocopherol inhibits the development of offspring food allergy, H1R signaling and ultimately anaphylaxis early in life., PMID:40073242

Depletion of eosinophils during sensitization but not challenge phase in mice blocks the development of food allergy early in life., PMID:40073088

Comment on "IL-21 and IL-33 May Be Effective Biomarkers to Predict the Efficacy of PD-1 Monoclonal Antibody for Advanced Cholangiocarcinoma"., PMID:40067408

Distinct roles for thymic stromal lymphopoietin (TSLP) and IL-33 in experimental eosinophilic esophagitis., PMID:40060399

Role and mechanism of IL-33 in bacteria infection related gastric cancer continuum: From inflammation to tumor progression., PMID:40058506

IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity., PMID:40048372

TL1A, a novel alarmin in airway, intestinal, and autoimmune disorders., PMID:40010414

Advances in Biologic Therapies for Allergic Diseases: Current Trends, Emerging Agents, and Future Perspectives., PMID:40004611

Assessing the inflammation in pediatric MOGAD: Significance of CSF HMGB1 and related biomarkers., PMID:39981242

IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy., PMID:39935481

IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential., PMID:39925809

Emerging biological treatments for asthma., PMID:39873193

Targeting alarmins in asthma: From bench to clinic., PMID:39855362

IL-21 and IL-33 May Be Effective Biomarkers to Predict the Efficacy of PD-1 Monoclonal Antibody for Advanced Cholangiocarcinoma., PMID:39835991

Baicalein attenuates ovalbumin-induced allergic rhinitis through the activation of nuclear receptor subfamily 4 group a member 1., PMID:39808359

Fibroblast growth factor 21 alleviated atopic march by inhibiting the differentiation of type 2 helper T cells., PMID:39798471

IL-33, a neutrophil extracellular trap-related gene involved in the progression of diabetic kidney disease., PMID:39797951

The evaluation of the serum levels of vitamin D and interleukin-33 in children with atopic dermatitis and its association with diseases severity., PMID:39775933

Long-term application of MC903 in mice prolongs the characteristic symptoms of atopic dermatitis, such as inflammation, skin barrier dysfunction, and itching., PMID:39721714

IL-33/ST2 axis mediates diesel exhaust particles-induced mast cell activation., PMID:39707175

IL-5-producing Group 2 innate lymphoid cells promote T cell-independent IgA production in cooperation with eosinophils., PMID:39656643

Adventitial Injection of Hyaluronic Acid/Sodium Alginate Hydrogel Loaded With IL-33 Antibody Decreases Neointimal Hyperplasia., PMID:39667249

NOD1 signaling regulates early tissue inflammation during helminth infection., PMID:39662675

Εosinophilic Chronic Obstructive Pulmonary Disease. What Do We Know So Far?, PMID:39661227

Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells., PMID:39632879

IL33-induced neutrophil extracellular traps (NETs) mediate a positive feedback loop for synovial inflammation and NET amplification in rheumatoid arthritis., PMID:39617790

Emerging Anti-Inflammatory COPD Treatments: Potential Cardiovascular Impacts., PMID:39606712

IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity., PMID:39605647

Datasheet
$ 328
Product specifications
100 μg 328 1 mg 1640

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Anti-Human IL33 Antibody (C2_2E12) [RHB74001]
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