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Anti-Human HCN4 Antibody (N114/10.1)

Catalog #:   RHC17201 Specific References (49) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IF, IHC, WB
Accession: Q9Y3Q4
Overview

Catalog No.

RHC17201

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Target

HCN4, Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9Y3Q4

Applications

IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

N114/10.1

Data Image
References

Hippo-Yap Signaling Maintains Sinoatrial Node Homeostasis., PMID:36317529

The Heart's Pacemaker Mimics Brain Cytoarchitecture and Function: Novel Interstitial Cells Expose Complexity of the SAN., PMID:36182566

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338

Identification of novel pulmonary vein nodes as generators of ectopic arrhythmic foci for atrial fibrillation: an immunohistochemical proof., PMID:34994828

Hedgehog signalling controls sinoatrial node development and atrioventricular cushion formation., PMID:34062094

Isolation and Culture of Resident Cardiac Macrophages from the Murine Sinoatrial and Atrioventricular Node., PMID:34028452

Whole-Mount Immunofluorescence Staining, Confocal Imaging and 3D Reconstruction of the Sinoatrial and Atrioventricular Node in the Mouse., PMID:33427243

Expression of the pacemaker channel HCN4 in excitatory interneurons in the dorsal horn of the murine spinal cord., PMID:32948209

HCN3 ion channels: roles in sensory neuronal excitability and pain., PMID:31290157

Cardiomyocyte Progenitor Cells as a Functional Gene Delivery Vehicle for Long-Term Biological Pacing., PMID:30621310

Characterizing the role of atrial natriuretic peptide signaling in the development of embryonic ventricular conduction system., PMID:29720615

HCN4-Overexpressing Mouse Embryonic Stem Cell-Derived Cardiomyocytes Generate a New Rapid Rhythm in Rats with Bradycardia., PMID:29628472

Telocytes in the human sinoatrial node., PMID:29148209

Expression and cellular localization of HCN channels in rat cerebellar granule neurons., PMID:27569278

Morphology of mouse sinoatrial node and its expression of NF-160 and HCN4., PMID:26550270

Decreased expression of hyperpolarisation-activated cyclic nucleotide-gated channel 3 in Hirschsprung's disease., PMID:25987789

Intrinsic and extrinsic innervation of the heart in zebrafish (Danio rerio)., PMID:25711945

Innervation of sinoatrial nodal cardiomyocytes in mouse. A combined approach using immunofluorescent and electron microscopy., PMID:25101952

Regional innervation of the heart in the goldfish, Carassius auratus: a confocal microscopy study., PMID:23853005

HCN4 dynamically marks the first heart field and conduction system precursors., PMID:23743334

Enhanced differentiation potential of human amniotic mesenchymal stromal cells by using three-dimensional culturing., PMID:23515591

Myocardial expression of hyperpolarization-activated, cyclic nucleotide-gated proteins in healthy cats and cats with hypertrophic cardiomyopathy., PMID:23385073

Hyperpolarisation-activated cyclic nucleotide channel 4 (HCN4) involvement in Tourette's syndrome autoimmunity., PMID:22683190

Remodeling of the peripheral cardiac conduction system in response to pressure overload., PMID:22307665

Thy1 associates with the cation channel subunit HCN4 in adult rat retina., PMID:22281825

Novel insights into the distribution of cardiac HCN channels: an expression study in the mouse heart., PMID:21945247

A case of cor triatriatum with an abnormal P wave: the pacemaker action from the specialized tissue in the abnormal septum., PMID:21823032

Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells., PMID:21456027

Bipolar cells of the ground squirrel retina., PMID:21246553

Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4., PMID:21220308

Overexpression of connexin 45 in rat mesenchymal stem cells improves the function as cardiac biological pacemakers., PMID:20819514

Hyperpolarization-activated and cyclic nucleotide-gated channels are differentially expressed in juxtaglomerular cells in the olfactory bulb of mice., PMID:20140458

Hyperpolarization-activated cyclic-nucleotide gated 4 (HCN4) protein is expressed in a subset of rat dorsal root and trigeminal ganglion neurons., PMID:19820968

Diabetes alters protein expression of hyperpolarization-activated cyclic nucleotide-gated channel subunits in rat nodose ganglion cells., PMID:19815055

Connexin 30 is expressed in the mouse sino-atrial node and modulates heart rate., PMID:19679680

Proteolytic processing of HCN2 and co-assembly with HCN4 in the generation of cardiac pacemaker channels., PMID:19574228

Transcriptional control of pacemaker channel genes HCN2 and HCN4 by Sp1 and implications in re-expression of these genes in hypertrophied myocytes., PMID:19471099

In situ co-distribution and functional interactions of SAP97 with sinoatrial isoforms of HCN channels., PMID:19336273

Histopathological substrate for chronic atrial fibrillation in humans., PMID:19324302

Involvement of hyperpolarization-activated, cyclic nucleotide-gated cation channels in dorsal root ganglion in neuropathic pain., PMID:18958363

Identification and distribution of interstitial Cajal cells in human pulmonary veins., PMID:18598966

Hyperpolarization-activated cyclic nucleotide-gated channel mRNA and protein expression in large versus small diameter dorsal root ganglion neurons: correlation with hyperpolarization-activated current gating., PMID:18450385

Type 3a and type 3b OFF cone bipolar cells provide for the alternative rod pathway in the mouse retina., PMID:17447251

Expression of hyperpolarization-activated cyclic nucleotide-gated cation channels in rat dorsal root ganglion neurons innervating urinary bladder., PMID:16979600

Hyperpolarization-activated cation channels are expressed in rat hypothalamic gonadotropin-releasing hormone (GnRH) neurons and immortalized GnRH neurons., PMID:16879992

The murine HCN3 gene encodes a hyperpolarization-activated cation channel with slow kinetics and unique response to cyclic nucleotides., PMID:15923185

Hyperpolarization-activated, cyclic nucleotide-gated cation channels: roles in the differential electrophysiological properties of rat primary afferent neurons., PMID:15139030

Expression of connexin36 in cone pedicles and OFF-cone bipolar cells of the mouse retina., PMID:15056712

HCN channels are expressed differentially in retinal bipolar cells and concentrated at synaptic terminals., PMID:12786975

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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Anti-Human HCN4 Antibody (N114/10.1) [RHC17201]
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