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Research Grade Naglazyme/Galsulfase (DHD13229)

Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Accession:P15848
Overview

Catalog No.

DHD13229

Expression system

Mammalian Cells

Species reactivity

Human

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Purified by Ion Exchange Chromatography.

Accession

P15848

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

G4S, ASB, N-acetylgalactosamine-4-sulfatase, ARSB, Arylsulfatase B

Clone ID

Naglazyme

Data Image
References

Galsulfase (Naglazyme) [Internet], PMID: 28121110

Lysosomal storage diseases, PMID: 29152458

Galsulfase (Naglazyme®) therapy in infants with mucopolysaccharidosis VI, PMID: 24108527

Galsulfase, PMID: 16521329

Intravenous Enzyme Replacement Therapy in Mucopolysaccharidoses: Clinical Effectiveness and Limitations, PMID: 32340185

Enzyme replacement therapy with galsulfase for mucopolysaccharidosis type VI, PMID: 26943923

Galsulfase: arylsulfatase B, BM 102, recombinant human arylsulfatase B, recombinant human N-acetylgalactosamine-4-sulfatase, rhASB, PMID: 16128602

Enzyme replacement therapy for mucopolysaccharidosis VI: long-term cardiac effects of galsulfase (Naglazyme®) therapy, PMID: 22669363

Mucopolysaccharidosis VI, PMID: 20385007

Comparison of neutralizing antibody assays for receptor binding and enzyme activity of the enzyme replacement therapeutic Naglazyme (galsulfase), PMID: 18709516

Rapid Desensitization for Immediate Hypersensitivity to Galsulfase Therapy in Patients with MPS VI, PMID: 26951141

Development, validation, and clinical implementation of an assay to measure total antibody response to naglazyme (galsulfase), PMID: 18607760

Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance, PMID: 31142378

Long-term galsulfase enzyme replacement therapy in Taiwanese mucopolysaccharidosis VI patients: A case series, PMID: 27134829

Mucopolysaccharidosis type VI phenotypes-genotypes and antibody response to galsulfase, PMID: 23557332

Reversed papilledema in an MPS VI patient with galsulfase (Naglazyme) therapy, PMID: 18418554

Is premedication a necessity before galsulfase replacement therapy?, PMID: 27346567

Successful desensitization in a type VI mucopolysaccharidosis patient with probable IgE-mediated allergy to galsulfase [Naglazyme], PMID: 23244660

Clinical effectiveness of enzyme replacement therapy with galsulfase in mucopolysaccharidosis type VI treatment: Systematic review, PMID: 30740728

Enzyme replacement therapy with galsulfase in 34 children younger than five years of age with MPS VI, PMID: 23535281

Successful management of difficult infusion-associated reactions in a young patient with mucopolysaccharidosis type VI receiving recombinant human arylsulfatase B (galsulfase [Naglazyme]), PMID: 18250117

Enzyme Replacement Therapy may Affect Blood Immunosuppressant Monitoring, PMID: 32379593

Enzyme replacement therapy initiated in adulthood: Findings from the mucopolysaccharidosis VI Clinical Surveillance Program, PMID: 31324526

The effect of galsulfase enzyme replacement therapy on the growth of patients with mucopolysaccharidosis VI (Maroteaux-Lamy syndrome), PMID: 28457718

Enzyme replacement therapy with galsulfase for mucopolysaccharidosis VI: clinical facts and figures, PMID: 21434527

Enzyme replacement therapy outcomes across the disease spectrum: Findings from the mucopolysaccharidosis VI Clinical Surveillance Program, PMID: 30834539

Therapy for the mucopolysaccharidoses, PMID: 22210671

Home treatment with Elaprase and Naglazyme is safe in patients with mucopolysaccharidoses types II and VI, respectively, PMID: 18923918

Lysosomal storage diseases, PMID: 18720909

Recent Advances in Treatment Approaches of Mucopolysaccharidosis VI, PMID: 21506914

Growth Charts for Individuals with Mucopolysaccharidosis VI (Maroteaux-Lamy Syndrome), PMID: 25518809

A systematic review of new advances in the management of mucopolysaccharidosis VI (Maroteaux-Lamy syndrome): focus on galsulfase, PMID: 19851471

Natural history and galsulfase treatment in mucopolysaccharidosis VI (MPS VI, Maroteaux-Lamy syndrome)--10-year follow-up of patients who previously participated in an MPS VI Survey Study, PMID: 24764221

Enzymes approved for human therapy: indications, mechanisms and adverse effects, PMID: 25648140

Maroteaux-Lamy syndrome (mucopolysaccharidosis type VI): a single dose of galsulfase further reduces urine glycosaminoglycans after hematopoietic stem cell transplantation, PMID: 20800524

Enzyme replacement therapy for the management of the mucopolysaccharidoses, PMID: 20040314

Long-term outcomes of patients with mucopolysaccharidosis VI treated with galsulfase enzyme replacement therapy since infancy, PMID: 33775523

[Enzyme replacement therapy of lysosomal storage diseases], PMID: 21211680

Early initiation of enzyme replacement therapy for the mucopolysaccharidoses, PMID: 24388732

Pharmacodynamics, pharmacokinetics and biodistribution of recombinant human N-acetylgalactosamine 4-sulfatase after 6months of therapy in cats using different IV infusion durations, PMID: 26776148

Thrombocytopenia associated with galsulfase treatment, PMID: 20670992

Current enzyme replacement therapy for the treatment of lysosomal storage diseases, PMID: 19725195

Home treatment of type VI mucopolysaccharidosis (Maroteaux-Lamy syndrome) an alternative at this time of COVID-19 pandemic: A case in Peru, PMID: 33363956

[Management of mucopolysaccharidosis type VI in adults], PMID: 26502669

[Mucopolysaccharidosis type VI: clinical aspects, diagnosis and treatment with enzyme replacement therapy], PMID: 24862809

[Cardiovascular findings and effects of enzyme replacement therapy in patients with mucopolysaccharidosis type VI], PMID: 31582674

Long-term impact of early initiation of enzyme replacement therapy in 34 MPS VI patients: A resurvey study, PMID: 33678523

Mucopolysaccharidosis type VI (Maroteaux-Lamy syndrome) with a predominantly cardiac phenotype, PMID: 21917494

Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis, PMID: 19852785

[Overview of enzyme replacement therapy in mucopolysaccharidosis], PMID: 17546776

Datasheet
$ 426
Product specifications
100 μg 426 1 mg 1704

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Research Grade Naglazyme/Galsulfase [DHD13229]
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