Catalog No.
DHE03429
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1-Fc
Clonality
Monoclonal
Target
CD80, BB1, T-lymphocyte activation antigen CD80, CD28LG, B7, CD28LG1, LAB7, Activation B7-1 antigen, CTLA-4 counter-receptor B7.1, BU63, B70, CD28LG2, CTLA-4 counter-receptor B7.2, Activation B7-2 antigen, T-lymphocyte activation antigen CD86, CD86, FUN-1
Concentration
2.29 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P33681 &/or P42081
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Abatacept
Trial of Upadacitinib or Abatacept in Rheumatoid Arthritis, PMID: 33053283
Abatacept: A Review in Rheumatoid Arthritis, PMID: 28608166
Abatacept for the treatment of rheumatoid arthritis, PMID: 30730220
How does abatacept really work in rheumatoid arthritis?, PMID: 29401118
Abatacept as a Long-Term Targeted Therapy for LRBA Deficiency, PMID: 31238161
[Abatacept], PMID: 27311187
Abatacept for Severe Immune Checkpoint Inhibitor-Associated Myocarditis, PMID: 31189043
Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial, PMID: 31342624
Abatacept in interstitial lung disease associated with rheumatoid arthritis: national multicenter study of 263 patients, PMID: 33068439
Abatacept for the treatment of psoriatic arthritis, PMID: 30246575
Abatacept: A Review of the Treatment of Polyarticular-Course Juvenile Idiopathic Arthritis, PMID: 33029724
Abatacept in the treatment of adult dermatomyositis and polymyositis: a randomised, phase IIb treatment delayed-start trial, PMID: 28993346
Comparative effectiveness of abatacept, apremilast, secukinumab and ustekinumab treatment of psoriatic arthritis: a systematic review and network meta-analysis, PMID: 29285605
Abatacept initiation in rheumatoid arthritis and the risk of cancer: a population-based comparative cohort study, PMID: 30535094
Abatacept in patients with rheumatoid arthritis and interstitial lung disease: A national multicenter study of 63 patients, PMID: 29422324
Trial of Upadacitinib or Abatacept in Rheumatoid Arthritis, PMID: 33406336
Comparative effectiveness of rituximab, abatacept, and tocilizumab in adults with rheumatoid arthritis and inadequate response to TNF inhibitors: prospective cohort study, PMID: 30679233
Comparative risk of malignancies and infections in patients with rheumatoid arthritis initiating abatacept versus other biologics: a multi-database real-world study, PMID: 31703717
Abatacept for Treatment of Rheumatoid Arthritis: Special Focus on the Elderly, PMID: 29651639
Abatacept in the treatment of psoriatic arthritis: biological and clinical profiles of the responders, PMID: 29737909
Abatacept in the treatment of localized scleroderma: A pediatric case series and systematic literature review, PMID: 32504991
A Randomized, Double-Blind Trial of Abatacept (CTLA-4Ig) for the Treatment of Giant Cell Arteritis, PMID: 28133925
CTLA4-Ig (abatacept): a promising investigational drug for use in type 1 diabetes, PMID: 32031422
The clinical effectiveness and cost-effectiveness of abatacept, adalimumab, etanercept and tocilizumab for treating juvenile idiopathic arthritis: a systematic review and economic evaluation, PMID: 27135404
Abatacept, PMID: 19843049
Abatacept for the treatment of systemic lupus erythematosus, PMID: 26878310
Comparative efficacy and safety of tocilizumab, rituximab, abatacept and tofacitinib in patients with active rheumatoid arthritis that inadequately responds to tumor necrosis factor inhibitors: a Bayesian network meta-analysis of randomized controlled trials, PMID: 26692536
Efficacy of abatacept for Felty's syndrome, PMID: 31292638
Abatacept for rheumatoid arthritis: a Cochrane systematic review, PMID: 20080922
Abatacept in rheumatoid arthritis and the risk of cancer: a world observational post-marketing study, PMID: 31880308
Abatacept Monotherapy Versus Abatacept Plus Methotrexate for Treatment-Refractory Rheumatoid Arthritis, PMID: 29023282
Malignant Neoplasms in Patients With Rheumatoid Arthritis Treated With Tumor Necrosis Factor Inhibitors, Tocilizumab, Abatacept, or Rituximab in Clinical Practice: A Nationwide Cohort Study From Sweden, PMID: 28975211
Abatacept reduces disease activity of rheumatoid arthritis independently of modulating anti-citrullinated peptide antibody production, PMID: 31994996
Practice guidelines for the use of subcutaneous abatacept, PMID: 24387951
Subcutaneous abatacept in rheumatoid arthritis: current update, PMID: 26160492
Abatacept induced granulomatous hepatitis with a sarcoidosis- like reaction: a blinded trial in mice, PMID: 31064410
Abatacept: A review of a new biologic agent for refractory rheumatoid arthritis for dermatologists, PMID: 16971318
JAK1 inhibitor superior to abatacept in head-to-head RA trial, PMID: 33110224
Abatacept alleviates rheumatoid arthritis development by inhibiting migration of fibroblast-like synoviocytes via MAPK pathway, PMID: 31002160
Evaluation of abatacept in biologic-naïve patients with active rheumatoid arthritis, PMID: 20099018
Joint involvement in systemic lupus erythematosus: From pathogenesis to clinical assessment, PMID: 28465078
Abatacept in rheumatoid arthritis: survival on drug, clinical outcomes, and their predictors-data from a large national quality register, PMID: 31969172
Does Abatacept Increase Postoperative Adverse Events in Rheumatoid Arthritis Compared with Conventional Synthetic Disease-modifying Drugs?, PMID: 31203226
Response to abatacept is associated with the inhibition of proteasome β1i expression in T cells of patients with rheumatoid arthritis, PMID: 32998980
Successful abatacept treatment for Felty's syndrome in a patient with rheumatoid arthritis, PMID: 33086993
Abatacept Use Is Associated with Steroid Dose Reduction and Improvement in Fatigue and CD4-Dysregulation in CVID Patients with Interstitial Lung Disease, PMID: 33223097
Therapeutic trials of biologics in primary biliary cholangitis: An open label study of abatacept and review of the literature, PMID: 31027870
Gene expression regulated by abatacept associated with methotrexate and correlation with disease activity in rheumatoid arthritis, PMID: 32760165
Abatacept as a successful therapy for myositis—a case-based review, PMID: 24493331
Abatacept retention and clinical outcomes in rheumatoid arthritis: real-world data from the German cohort of the ACTION study and a comparison with other participating countries, PMID: 31300979
For research use only. Not for human or drug use.
