Catalog No.
EVV07801
Expression system
Mammalian Cells
Species
Human immunodeficiency virus type 1 (HIV-1)
Protein length
Ala29-Arg513
Predicted molecular weight
57.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9YUL5
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
env, Envelope glycoprotein gp160, Envelope glycoprotein gp160, Env polyprotein, Surface protein gp120, Glycoprotein 120, gp120, Transmembrane protein gp41, Glycoprotein 41, gp41
Hidden dUTPase sequence in human immunodeficiency virus type 1 gp120. PMID: 9847382
HIV-1 gp120 and immune network. PMID: 15370273
The alpha helix 1 from the first conserved region of HIV1 gp120 is reconstructed in the short NQ21 peptide. PMID: 29273432
The HIV-1 gp120 V1V2 loop: structure, function and importance for vaccine development. PMID: 25163695
Entry inhibitors directed towards glycoprotein gp120: an overview on a promising target for HIV-1 therapy. PMID: 23278399
The SPL7013 dendrimer destabilizes the HIV-1 gp120-CD4 complex. PMID: 26495445
HIV gp120: double lock strategy foils host defences. PMID: 9739096
Mutational pressure makes HIV1 gp120 linear B-cell epitopes shorter and may lead to their disappearance. PMID: 20129670
Gp120 on HIV-1 Virions Lacks O-Linked Carbohydrate. PMID: 25915761
Plugging gp120s cavity. PMID: 19000812
Molecular mechanism of HIV-1 gp120 mutations that reduce CD4 binding affinity. PMID: 23297802
Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug. PMID: 21345545
Computational design, synthesis and evaluation of new sulphonamide derivatives targeting HIV-1 gp120. PMID: 31792886
NMR observation of HIV-1 gp120 conformational flexibility resulting from V3 truncation. PMID: 24819826
A modeled structure of an aptamer-gp120 complex provides insight into the mechanism of HIV-1 neutralization. PMID: 20527993
Variability in the Glycosylation Patterns of gp120 Proteins from Different Human Immunodeficiency Virus Type 1 Isolates Expressed in Different Host Cells. PMID: 34448591
The β20-β21 of gp120 is a regulatory switch for HIV-1 Env conformational transitions. PMID: 29051495
gp120: Biologic aspects of structural features. PMID: 11244037
Genetic variability of HIV-1. PMID: 8883605
[Structural mechanism of immune evasion of HIV-1 gp120 by genomic, computational, and experimental science]. PMID: 21972555
Allosteric induction of the CD4-bound conformation of HIV-1 Gp120. PMID: 24304511
Structure and Dynamics of the Native HIV-1 Env Trimer. PMID: 25762739
Potential drug targets on the HIV-1 envelope glycoproteins, gp120 and gp41. PMID: 12769725
The gp120 protein is a second determinant of decreased neurovirulence of Indian HIV-1C isolates compared to southern African HIV-1C isolates. PMID: 25188269
A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4. PMID: 28429756
The HIV-1 gp120 major variable regions modulate cold inactivation. PMID: 23345516
Conformational characterization of aberrant disulfide-linked HIV-1 gp120 dimers secreted from overexpressing cells. PMID: 20471426
The V1/V2 loop of HIV-1 gp120 is necessary for Tat binding and consequent modulation of virus entry. PMID: 23916815
Structure-based design, synthesis and validation of CD4-mimetic small molecule inhibitors of HIV-1 entry: conversion of a viral entry agonist to an antagonist. PMID: 24502450
Structures of HIV-1 gp120 envelope glycoproteins from laboratory-adapted and primary isolates. PMID: 11188697
Structure of HIV-1 gp120 with gp41-interactive region reveals layered envelope architecture and basis of conformational mobility. PMID: 20080564
Stoichiometric parameters of HIV-1 entry. PMID: 25463598
Insight derived from molecular dynamics simulations into molecular motions, thermodynamics and kinetics of HIV-1 gp120. PMID: 25105502
[Structure and function of oligosaccharide chains of the envelope glycoprotein gp120 of human immunodeficiency virus type 1]. PMID: 1518160
The V1V2 Region of HIV-1 gp120 Forms a Five-Stranded Beta Barrel. PMID: 26018158
Binding of HIV-1 gp120 glycoprotein to silica nanoparticles modified with CD4 glycoprotein and CD4 peptide fragments. PMID: 22117536
Local conformational stability of HIV-1 gp120 in unliganded and CD4-bound states as defined by amide hydrogen/deuterium exchange. PMID: 20660185
Conformation of gp120 determines the sensitivity of HIV-1 DH012 to the entry inhibitor IC9564. PMID: 15207637
Characterization of the secreted, native gp120 and gp160 of the human immunodeficiency virus type 1. PMID: 2187500
Correlated mutations at gp120 positions 322 and 440: implications for gp120 structure. PMID: 18275085
Morphometric analysis of envelope glycoprotein gp120 distribution on HIV-1 virions. PMID: 7678271
Nonneutralizing antibodies to the CD4-binding site on the gp120
For research use only. Not for human or drug use.
