Catalog No.
AID00201
Description
Desmoglein 1 (DSG1), the Pemphigus Foliaceus (PF) antigen, is produced as a precursor (preDSG1) and is transported to the cell surface as the mature form (matDSG1). Pemphigus foliaceus (PF) is an organ-specific autoimmune cutaneous disease characterized clinically by the development of superficial blisters and erosions of skin, histologically by loss of cell adhesion of keratinocytes in the upper part of epidermis, and immunologically by in vivo bound and circulating IgG autoantibodies directed against desmoglein 1 (Dsg1), a transmembrane desmosomal glycoprotein to the cadherin family.
Expression system
Confidential
Species
Homo sapiens (Human)
Protein length
Confidential
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Applications
As a diagnostic tool for Pemphigus Foliaceus (PF).
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
DGI, Cadherin family member 4, Desmoglein-1, DG1, Pemphigus foliaceus antigen, CDHF4, DSG1, Desmosomal glycoprotein 1
For research use only. Not for human or drug use.
