Catalog No.
EHJ51601
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Ser19-Ser740
Predicted molecular weight
85.2 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>80% as determined by SDS-PAGE.
Accession
Q9BYF1
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Angiotensin-converting enzyme homolog, ACE2, ACEH, Metalloprotease MPROT15, Angiotensin-converting enzyme-related carboxypeptidase, Angiotensin-converting enzyme 2, ACE-related carboxypeptidase, SARS-like Coronaviruses
Unraveling the Role of ACE2, the Binding Receptor for SARS-CoV-2, in Inflammatory Bowel Disease. PMID: 33064147
Cross-species recognition of SARS-CoV-2 to bat ACE2. PMID: 33335073
An update on ACE2 amplification and its therapeutic potential. PMID: 32469114
Interaction between the apelinergic system and ACE2 in the cardiovascular system: therapeutic implications. PMID: 32901821
Involvement of ACE2/Ang-(1-7)/MAS1 Axis in the Regulation of Ovarian Function in Mammals. PMID: 32604999
The ACE2/Ang (1-7)/MasR axis as an emerging target for antihypertensive peptides. PMID: 32551837
Targeting ACE2 for COVID-19 Therapy: Opportunities and Challenges. PMID: 33296619
ACE2 in the second act of COVID-19 syndrome: Peptide dysregulation and possible correction with oestrogen. PMID: 33462852
Kidney ACE2 expression: Implications for chronic kidney disease. PMID: 33125431
Cytoplasmic short linear motifs in ACE2 and integrin beta(3) link SARS-CoV-2 host cell receptors to mediators of endocytosis and autophagy. PMID: 33436498
Inhaled corticosteroids downregulate the SARS-CoV-2 receptor ACE2 in COPD through suppression of type I interferon. PMID: 33068560
The expression of SARS-CoV-2 receptor ACE2 and CD147, and protease TMPRSS2 in human and mouse brain cells and mouse brain tissues. PMID: 33008593
ACE2 role in SARS-CoV-2 infectivity and Covid-19 severity. PMID: 33361716
ACE2: The Major Cell Entry Receptor for SARS-CoV-2. PMID: 33170317
ACE2 in the renin-angiotensin system. PMID: 33264412
ACE2, angiotensin 1-7 and skeletal muscle: review in the era of COVID-19. PMID: 33231620
ACE2 as therapeutic agent. PMID: 33063820
Epigenetic regulation of ACE2, the receptor of the SARS-CoV-2 virus(1). PMID: 33086021
Engineered ACE2 receptor traps potently neutralize SARS-CoV-2. PMID: 33093202
COVID-19: angiotensin-converting enzyme 2 (ACE2) expression and tissue susceptibility to SARS-CoV-2 infection. PMID: 33389262
Structural variations in human ACE2 may influence its binding with SARS-CoV-2 spike protein. PMID: 32249956
ACE2 contributes to the maintenance of mouse epithelial barrier function. PMID: 33097186
ACE2: from protection of liver disease to propagation of COVID-19. PMID: 33284956
ACE2 Attenuates Epithelial-Mesenchymal Transition in MLE-12 Cells Induced by Silica. PMID: 32368013
Advances in research on ACE2 as a receptor for 2019-nCoV. PMID: 32780149
Molecules in pathogenesis: angiotensin converting enzyme 2 (ACE2). PMID: 32759311
Expression of ACE2 in airways: Implication for COVID-19 risk and disease management in patients with chronic inflammatory respiratory diseases. PMID: 32975865
SARS-CoV-2 Cell Entry Factors ACE2 and TMPRSS2 Are Expressed in the Microvasculature and Ducts of Human Pancreas but Are Not Enriched in beta Cells. PMID: 33207245
ACE2: Its potential role and regulation in severe acute respiratory syndrome and COVID-19. PMID: 32901940
ACE2 modulates glucose homeostasis through GABA signaling during metabolic stress. PMID: 32698150
Hypertension and renin-angiotensin system blockers are not associated with expression of angiotensin-converting enzyme 2 (ACE2) in the kidney. PMID: 33206176
The flexibility of ACE2 in the context of SARS-CoV-2 infection. PMID: 33189680
Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection. PMID: 33177651
Rationale for the use of N-acetylcysteine in both prevention and adjuvant therapy of COVID-19. PMID: 32780893
ACE2 activators for the treatment of COVID 19 patients. PMID: 32379346
The role of SARS-CoV-2 target ACE2 in cardiovascular diseases. PMID: 33443816
Angiotensin-converting enzyme 2 (ACE2), angiotensin-(1-7) and Mas receptor in gonadal and reproductive functions. PMID: 33196086
GB-2 inhibits ACE2 and TMPRSS2 expression: In vivo and in vitro studies. PMID: 33049583
Designed variants of ACE2-Fc that decouple anti-SARS-CoV-2 activities from unwanted cardiovascular effects. PMID: 33080267
ACE2 (Angiotensin-Converting Enzyme 2) and TMPRSS2 (Transmembrane Serine Protease 2) Expression and Localization of SARS-CoV-2 Infection in the Human Heart. PMID: 33086866
ACE2 and prognosis of COVID-19: Insights from Bartter's and Gitelman's syndromes patients. PMID: 32374416
Pirfenidone: A novel hypothetical treatment for COVID-19. PMID: 32575019
The ACE2 expression in Sertoli cells and germ cells may cause male reproductive disorder after SARS-CoV-2 infection. PMID: 32594644
SARS-CoV-2 spike protein favors ACE2 from Bovidae and Cricetidae. PMID: 32239522
Conformational dynamics of SARS-CoV-2 trimeric spike glycoprotein in complex with receptor ACE2 revealed by cryo-EM. PMID: 33277323
Interferons and viruses induce a novel truncated ACE2 isoform and not the full-length SARS-CoV-2 receptor. PMID: 33077916
ACE2, a multifunctional protein - from cardiovascular regulation to COVID-19. PMID: 33305790
ACE2/Angiotensin-(1-7)/Mas Receptor Axis in Human Cancer: Potential Role for Pediatric Tumors. PMID: 32039680
Protein structure analysis of the interactions between SARS-CoV-2 spike protein and the human ACE2 receptor: from conformational changes to novel neutralizing antibodies. PMID: 32623480
Rationally Designed ACE2-Derived Peptides Inhibit SARS-CoV-2. PMID: 33356169
For research use only. Not for human or drug use.
