Catalog No.
RHM03034
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Target
HLAA,Human leukocyte antigen A,HLA class I histocompatibility antigen,A alpha chain,HLA-A,Alpha-fetoprotein,Alpha-1-fetoprotein,Alpha-fetoglobulin,AFP,HPAFP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P04439 & P02771
Applications
ELISA, SPR
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
AMC-79
Solution mapping of MHC-I:TCR interactions using a minimalistic protein system., PMID:40489613
Targeting intracellular LMP2 with costimulatory signal-armed antibody-like TCR T cells., PMID:40401520
Unraveling CD8+ T cell alloimmunity: Insights into the direct pathway of antigen recognition from modern experimental tools., PMID:40373878
Immunogenicity of Trypanosoma cruzi Multi-Epitope Recombinant Protein as an Antigen Candidate for Chagas Disease Vaccine in Humans., PMID:40333154
Application of Humanized MHC Transgenic Mice in the Screening of HLA-Restricted T Cell Epitopes for Influenza Vaccines., PMID:40266241
Mimicry-based strategy between human and commensal antigens for the development of a new family of immune therapies for cancer., PMID:39979071
Immunotherapy targeting a leader sequence cathepsin G-derived peptide., PMID:39939820
Unveiling cross-reactivity: implications for immune response modulation in cancer., PMID:39831892
Preclinical model for evaluating human TCRs against chimeric syngeneic tumors., PMID:39794936
Exploring red blood cells as an antigen delivery system to modulate the immune response towards FVIII in hemophilia A., PMID:39617188
Major histocompatibility complex and peptide specificity underpin CD8+ T cell direct alloresponse., PMID:39433089
A combination of major histocompatibility complex (MHC) I overexpression and type I interferon induce mitochondrial dysfunction in human skeletal myoblasts., PMID:39382090
First-in-human clinical trial results with ABBV-184, a first-in-class T-cell receptor/anti-CD3 bispecific protein, in adults with previously treated AML or NSCLC., PMID:38946484
TransfIGN: A Structure-Based Deep Learning Method for Modeling the Interaction between HLA-A*02:01 and Antigen Peptides., PMID:38920330
Generation and evaluation of cancer binding capacity of HLA-A2-WT1 complex-targeting antibody., PMID:38810886
Potent antitumor activity of a bispecific T-cell engager antibody targeting the intracellular antigen KRAS G12V., PMID:38752985
Diverse cytomegalovirus US11 antagonism and MHC-A evasion strategies reveal a tit-for-tat coevolutionary arms race in hominids., PMID:38377192
Development of therapeutic monoclonal antibodies against DKK1 peptide-HLA-A2 complex to treat human cancers., PMID:38267222
Unsupervised and supervised AI on molecular dynamics simulations reveals complex characteristics of HLA-A2-peptide immunogenicity., PMID:38233090
A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML., PMID:38048594
Thioamide Analogues of MHC I Antigen Peptides., PMID:37968794
SARS-CoV-2 infection establishes a stable and age-independent CD8+ T cell response against a dominant nucleocapsid epitope using restricted T cell receptors., PMID:37872153
Vaccination with post-translational modified, homocitrullinated peptides induces CD8 T-cell responses that mediate antitumor immunity., PMID:37857526
Immune-infiltrated kidney organoid-on-chip model for assessing T cell bispecific antibodies., PMID:37603766
Usefulness of Docking and Molecular Dynamics in Selecting Tumor Neoantigens to Design Personalized Cancer Vaccines: A Proof of Concept., PMID:37514989
ABBV-184: A Novel Survivin-specific TCR/CD3 Bispecific T-cell Engager is Active against Both Solid Tumor and Hematologic Malignancies., PMID:37294945
Immune engineered extracellular vesicles to modulate T cell activation in the context of type 1 diabetes., PMID:37267353
Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM., PMID:37100770
Persistent CD8 T Cell Marks Caused by the HCMV Infection in Seropositive Adults: Prevalence of HLA-E-Reactive CD8 T Cells., PMID:36980230
Validation of Ligand Tetramers for the Detection of Antigen-Specific Lymphocytes., PMID:36883850
A flexible liposomal polymer complex as a platform of specific and regulable immune regulation for individual cancer immunotherapy., PMID:36691089
The Intracellular Proteome as a Source for Novel Targets in CAR-T and T-Cell Engagers-Based Immunotherapy., PMID:36611821
Nanobody-based CAR T cells targeting intracellular tumor antigens., PMID:36411612
Multi-Omic Analysis of Two Common P53 Mutations: Proteins Regulated by Mutated P53 as Potential Targets for Immunotherapy., PMID:36010968
Combined treatment with epigenetic agents enhances anti-tumor activity of MAGE-D4 peptide-specific T cells by upregulating the MAGE-D4 expression in glioma., PMID:35992806
Therapeutic targeting of PRAME with mTCRCAR T cells in acute myeloid leukemia., PMID:35984639
Physical and in silico immunopeptidomic profiling of a cancer antigen prostatic acid phosphatase reveals targets enabling TCR isolation., PMID:35878026
The Use of Molecular Dynamics Simulation Method to Quantitatively Evaluate the Affinity between HBV Antigen T Cell Epitope Peptides and HLA-A Molecules., PMID:35563019
Structural patterns in class 1 major histocompatibility complex-restricted nonamer peptide binding to T-cell receptors., PMID:35403257
Development of a TCR-like antibody and chimeric antigen receptor against NY-ESO-1/HLA-A2 for cancer immunotherapy., PMID:35338087
Production and purification of infectious diseases-associated tetramer for staining of CD8+ T cells from PBMCs., PMID:35284834
A TCR mimic monoclonal antibody reactive with the "public" phospho-neoantigen pIRS2/HLA-A*02:01 complex., PMID:35260532
Targeting an alternate Wilms' tumor antigen 1 peptide bypasses immunoproteasome dependency., PMID:35138909
T cell receptors employ diverse strategies to target a p53 cancer neoantigen., PMID:35124005
Development of antigen-prediction algorithm for personalized neoantigen vaccine using human leukocyte antigen transgenic mouse., PMID:35122353
Development of a Spontaneous HPV16 E6/E7-Expressing Head and Neck Squamous Cell Carcinoma in HLA-A2 Transgenic Mice., PMID:35089069
Chimeric Antigen Receptors Directed at Mutant KRAS Exhibit an Inverse Relationship Between Functional Potency and Neoantigen Selectivity., PMID:36860694
Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors., PMID:35013235
Mapping and Characterization of HCMV-Specific Unconventional HLA-E-Restricted CD8 T Cell Populations and Associated NK and T Cell Responses Using HLA/Peptide Tetramers and Spectral Flow Cytometry., PMID:35008688
ERAP1 Controls the Interaction of the Inhibitory Receptor KIR3DL1 With HLA-B51:01 by Affecting Natural Killer Cell Function., PMID:34917091
For research use only. Not for human or drug use.
