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Research Grade Tafasitamab (DHD10803)

Host species:Humanized
Isotype:IgG1-G2-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHD10803

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-G2-kappa

Clonality

Monoclonal

Target

CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4

Concentration

6.03 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P15391

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CD19, MOR-00208, MOR-208, XENP-5574, XMP-5574, XmAb-5574, Xmab-CD19, CAS: 1422527-84-1

Clone ID

Tafasitamab

Data Image
  • SDS-PAGE
    SDS PAGE for Tafasitamab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Tafasitamab plus lenalidomide in relapsed or refractory diffuse large B-cell lymphoma (L-MIND): a multicentre, prospective, single-arm, phase 2 study, PMID: 32511983

Tafasitamab: First Approval, PMID: 32946059

Tafasitamab-cxix, PMID: 33016999

Tafasitamab, PMID: 33355731

Antibodies to watch in 2020, PMID: 31847708

Novel Therapies for Relapsed or Refractory Diffuse Large B-Cell Lymphoma, PMID: 33202794

Challenges and Opportunities in the Management of Diffuse Large B-Cell Lymphoma in Older Patients, PMID: 33230948

The use of tafasitamab in diffuse large B-cell lymphoma, PMID: 34285786

Phase IIa study of the CD19 antibody MOR208 in patients with relapsed or refractory B-cell non-Hodgkin's lymphoma, PMID: 29444231

Tafasitamab for the treatment of relapsed or refractory diffuse large B-cell lymphoma, PMID: 33554668

Tafasitamab combined with idelalisib or venetoclax in patients with CLL previously treated with a BTK inhibitor, PMID: 34414843

Diffuse Large B-cell Lymphoma Responds to Tafasitamab plus Lenalidomide, PMID: 34376434

A phase 2a, single-arm, open-label study of tafasitamab, a humanized, Fc-modified, anti-CD19 antibody, in patients with relapsed/refractory B-precursor cell acute lymphoblastic leukemia, PMID: 34343354

RE-MIND: Comparing tafasitamab + lenalidomide (L-MIND) with a real‑world lenalidomide monotherapy cohort in relapsed or refractory diffuse large B-cell lymphoma, PMID: 34433649

Long-term outcomes from the Phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma, PMID: 34196165

Anti-CD19 CAR T-cell therapy remission despite prior anti-CD19 antibody Tafasitamab in relapsed/refractory DLBCL, PMID: 34354920

Long-term outcomes from the phase II L-MIND study of tafasitamab (MOR208) plus lenalidomide in patients with relapsed or refractory diffuse large B-cell lymphoma, PMID: 34407608

Enhancing CDC and ADCC of CD19 Antibodies by Combining Fc Protein-Engineering with Fc Glyco-Engineering, PMID: 33212776

Diffuse large B-cell lymphoma: new targets and novel therapies, PMID: 33820908

Lenalidomide in DLBCL: are we past the cell of origin?, PMID: 33989279

Incorporating Novel Targeted and Immunotherapeutic Agents in Treatment of B-Cell Lymphomas, PMID: 33770460

The Fc-engineered CD19 antibody MOR208 (XmAb5574) induces natural killer cell-mediated lysis of acute lymphoblastic leukemia cells from pediatric and adult patients, PMID: 23277329

Single-agent MOR208 salvage and maintenance therapy in a patient with refractory/relapsing diffuse large B-cell lymphoma: a case report, PMID: 27178351

Datasheet

Document Download

Research Grade Tafasitamab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Tafasitamab [DHD10803]
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