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Research Grade Bamlanivimab (DVV00303)

Host species:Human
Isotype:IgG1, kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DVV00303

Expression system

Mammalian Cells

Species reactivity

SARS-CoV-2 (2019-nCoV)

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

Spike glycoprotein, S glycoprotein, E2, Peplomer protein, Spike protein S1, Spike protein S2, Spike protein S2', S, 2

Concentration

1.07 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P0DTC2

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

LY-3819253, LY-CoV555, LY3819253, CAS: 2423943-37-5

Clone ID

Bamlanivimab

Data Image
  • SDS-PAGE
    SDS PAGE for Bamlanivimab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial, PMID: 33475701

Bamlanivimab, PMID: 33226744

An EUA for Bamlanivimab-A Monoclonal Antibody for COVID-19, PMID: 33306087

Covid-19: FDA authorises neutralising antibody bamlanivimab for non-admitted patients, PMID: 33177042

SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19, PMID: 33113295

Antimicrobial stewardship and bamlanivimab: Opportunities for outpatient preauthorization?, PMID: 33213544

COVID-19 vaccines: The status and perspectives in delivery points of view, PMID: 33359141

Anti-SARS-CoV-2 neutralizing monoclonal antibodies: clinical pipeline, PMID: 33319649

Antibodies to watch in 2021, PMID: 33459118

An EUA for bamlanivimab - a monoclonal antibody for COVID-19, PMID: 33443490

A Neutralizing Monoclonal Antibody for Hospitalized Patients with Covid-19, PMID: 33356051

Bamlanivimab for Prevention of COVID-19, PMID: 34081075

Bamlanivimab Use in a Military Treatment Facility, PMID: 33993281

Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19, PMID: 34260849

Expanded Access Programs, compassionate drug use, and Emergency Use Authorizations during the COVID-19 pandemic, PMID: 33253920

Efficacy of Bamlanivimab in Reducing Hospitalization and Mortality Rates in COVID-19 Patients in a Rural Community, PMID: 34430093

Etesevimab and Bamlanivimab, PMID: 33630482

Effect of Bamlanivimab vs Placebo on Incidence of COVID-19 Among Residents and Staff of Skilled Nursing and Assisted Living Facilities: A Randomized Clinical Trial, PMID: 34081073

A Narrative Review of the Clinical Practicalities of Bamlanivimab and Etesevimab Antibody Therapies for SARS-CoV-2, PMID: 34374951

Real-World Experience of Bamlanivimab for COVID-19: A Case-Control Study, PMID: 33846730

Initial Guidance on Use of Monoclonal Antibody Therapy for Treatment of Coronavirus Disease 2019 in Children and Adolescents, PMID: 33388760

Intravenous bamlanivimab use associates with reduced hospitalization in high-risk patients with mild to moderate COVID-19, PMID: 34411003

An EUA for bamlanivimab and etesevimab for COVID-19, PMID: 33830966

Bamlanivimab as monotherapy in two immunocompromised patients with COVID-19, PMID: 34341781

Impact of Bamlanivimab Monoclonal Antibody Treatment on Hospitalization and Mortality Among Nonhospitalized Adults With Severe Acute Respiratory Syndrome Coronavirus 2 Infection, PMID: 34250192

Bamlanivimab For Mild to Moderate COVID-19 in Kidney Transplant Recipients, PMID: 34222731

Association of Intravenous Bamlanivimab Use with Reduced Hospitalization, Intensive Care Unit Admission, and Mortality in Patients with Mild to Moderate COVID-19, PMID: 34075387

Bamlanivimab infusion experience at one academic emergency department, PMID: 34294501

Bamlanivimab use in mild-to-moderate COVID-19 disease: A matched cohort design, PMID: 34328670

Diffuse C4d staining of peritubular capillaries in renal allograft following bamlanivimab therapy, PMID: 34358400

Etesevimab, PMID: 34283469

First in Human Study of Bamlanivimab in a Randomized Trial of Hospitalized Patients with COVID-19, PMID: 34455583

Initial experience of bamlanivimab monotherapy use in solid organ transplant recipients, PMID: 34081820

Bamlanivimab for treatment of COVID-19 in solid organ transplant recipients: Early single-center experience, PMID: 33595145

Efficacy of Bamlanivimab/Etesevimab and Casirivimab/Imdevimab in Preventing Progression to Severe COVID-19 and Role of Variants of Concern, PMID: 34435337

Emergence of the E484K mutation in SARS-COV-2-infected immunocompromised patients treated with bamlanivimab in Germany, PMID: 34278371

Bamlanivimab treatment leads to rapid selection of immune escape variant carrying E484K mutation in a B.1.1.7 infected and immunosuppressed patient, PMID: 34009286

The Efficacy of Bamlanivimab in Reducing Emergency Department Visits and Hospitalizations in a Real-world Setting, PMID: 34258324

Consequences of rush to emergency use authorization of bamlanivimab, PMID: 34216205

501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab in vitro, PMID: 33619479

Emergency Use Authorization for Bamlanivimab in Mild to Moderate COVID-19: Implications for CNS Practice, PMID: 33793179

501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro, PMID: 34074219

Administration of Bamlanivimab to Skilled Nursing Facility Residents During a COVID-19 Outbreak, January-February 2021, Arizona, PMID: 34000267

Emergency Use Authorization for Bamlanivimab in Mild to Moderate COVID-19: Implications for Clinical Nurse Specialist Practice, PMID: 33793172

Real-World Clinical Outcomes of Bamlanivimab and Casirivimab-Imdevimab among High-Risk Patients with Mild to Moderate Coronavirus Disease 2019, PMID: 34279629

An overview of the preclinical discovery and development of bamlanivimab for the treatment of novel coronavirus infection (COVID-19): reasons for limited clinical use and lessons for the future, PMID: 34304682

Emergence of E484K Mutation Following Bamlanivimab Monotherapy among High-Risk Patients Infected with the Alpha Variant of SARS-CoV-2, PMID: 34452507

Clinical Impact of the Early Use of Monoclonal Antibody LY-CoV555 (Bamlanivimab) on Mortality and Hospitalization Among Elderly Nursing Home Patients: A Multicenter Retrospective Study, PMID: 33981518

Emergence of Q493R mutation in SARS-CoV-2 spike protein during bamlanivimab/etesevimab treatment and resistance to viral clearance, PMID: 34437928

SARS-CoV-2 variant B.1.617 is resistant to bamlanivimab and evades antibodies induced by infection and vaccination, PMID: 34270919

Datasheet

Document Download

Research Grade Bamlanivimab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Bamlanivimab [DVV00303]
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