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Research Grade Elotuzumab (DHJ64001)

Host species:Humanized
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHJ64001

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

SLAMF7, CRACC, Protein 19A, SLAM family member 7, CD2-like receptor-activating cytotoxic cells, Membrane protein FOAP-12, CD319, Novel Ly9, CD2 subset 1, CS1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q9NQ25

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BMS-901608, PDL063, HuLuc63, CAS: 915296-00-3

Clone ID

Elotuzumab

Data Image
  • Bioactivity
    Detects Human CD319/SLAMF7 in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Elotuzumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma, PMID: 30403938

Elotuzumab Therapy for Relapsed or Refractory Multiple Myeloma, PMID: 26035255

The Clinical Pharmacology of Elotuzumab, PMID: 28779463

Elotuzumab, PMID: 31644037

Elotuzumab: A Review in Relapsed and/or Refractory Multiple Myeloma, PMID: 30232695

Mechanisms of NK Cell Activation and Clinical Activity of the Therapeutic SLAMF7 Antibody, Elotuzumab in Multiple Myeloma, PMID: 30455698

Elotuzumab, PMID: 29999843

Bortezomib, lenalidomide, and dexamethasone with or without elotuzumab in patients with untreated, high-risk multiple myeloma (SWOG-1211): primary analysis of a randomised, phase 2 trial, PMID: 33357482

The role of elotuzumab in the treatment of relapsed or refractory multiple myeloma, PMID: 29317395

Elotuzumab, lenalidomide, and dexamethasone in RRMM: final overall survival results from the phase 3 randomized ELOQUENT-2 study, PMID: 32887873

Elotuzumab in combination with pomalidomide and dexamethasone for the treatment of multiple myeloma, PMID: 31679403

Elotuzumab plus lenalidomide and dexamethasone in relapsed/refractory multiple myeloma: Extended 4-year follow-up and analysis of relative progression-free survival from the randomized ELOQUENT-2 trial, PMID: 30204239

Elotuzumab: First Global Approval, PMID: 26809244

Elotuzumab for the Treatment of Relapsed or Refractory Multiple Myeloma, with Special Reference to its Modes of Action and SLAMF7 Signaling, PMID: 29531651

Elotuzumab as a novel anti-myeloma immunotherapy, PMID: 28604269

Elotuzumab: the first approved monoclonal antibody for multiple myeloma treatment, PMID: 27493709

Elotuzumab-based maintenance therapy following autologous stem cell transplant in multiple myeloma deepens post-transplant responses, PMID: 32745939

Development of [ 89 Zr]DFO-elotuzumab for immunoPET imaging of CS1 in multiple myeloma, PMID: 33179150

Elotuzumab for the treatment of multiple myeloma, PMID: 27417553

Update on elotuzumab for the treatment of relapsed/refractory multiple myeloma: patients' selection and perspective, PMID: 31410026

Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory MM, PMID: 27091875

Efficacy and safety of elotuzumab for the treatment of multiple myeloma, PMID: 28060563

Elotuzumab in multiple myeloma, PMID: 30449660

Multiple Myeloma: Diagnosis and Treatment, PMID: 26763514

Second elotuzumab triplet efficacious in MM, PMID: 30478425

Treatment of multiple myeloma with the immunostimulatory SLAMF7 antibody elotuzumab, PMID: 27695618

Spotlight on elotuzumab in the treatment of multiple myeloma: the evidence to date, PMID: 27785050

Daratumumab, Elotuzumab, and the Development of Therapeutic Monoclonal Antibodies in Multiple Myeloma, PMID: 27806428

Elotuzumab: a novel immune-stimulating therapy to treat multiple myeloma, PMID: 27322214

Elotuzumab: a novel anti-CS1 monoclonal antibody for the treatment of multiple myeloma, PMID: 24151843

Immunotherapy: A New Approach to Treating Multiple Myeloma with Daratumumab and Elotuzumab, PMID: 27083916

Update on elotuzumab, a novel anti-SLAMF7 monoclonal antibody for the treatment of multiple myeloma, PMID: 27533882

Toward further simplification of elotuzumab therapy by subcutaneous administration, PMID: 32656639

Treatment of relapsed and refractory multiple myeloma, PMID: 32719176

Model-Based Determination of Elotuzumab Pharmacokinetics in Japanese Patients With Multiple Myeloma Incorporating Time-Varying M Protein, PMID: 32656777

Treatment of relapsed multiple myeloma: Evidence-based recommendations, PMID: 31500848

Mechanisms of Action and Clinical Development of Elotuzumab, PMID: 29272564

Elotuzumab in the treatment of relapsed and refractory multiple myeloma, PMID: 33478270

Frequent occurrence of hypophosphatemia among multiple myeloma patients treated with elotuzumab: a single clinic retrospective study, PMID: 33237342

Sequence matters: elotuzumab more effective if used before daratumumab, PMID: 31845607

How to Integrate Elotuzumab and Daratumumab Into Therapy for Multiple Myeloma, PMID: 27998219

Managing Infusion Reactions to New Monoclonal Antibodies in Multiple Myeloma: Daratumumab and Elotuzumab, PMID: 29996069

Elotuzumab for the treatment of multiple myeloma, PMID: 24941981

Elotuzumab and daratumumab: emerging new monoclonal antibodies for multiple myeloma, PMID: 24053207

Emerging immunotherapies in multiple myeloma, PMID: 32958461

Targeting B Cell Maturation Antigen (BCMA) in Multiple Myeloma: Potential Uses of BCMA-Based Immunotherapy, PMID: 30147690

Elotuzumab: The First Monoclonal Antibody for the Treatment of Multiple Myeloma, PMID: 29282429

A review discussing elotuzumab and its use in the second-line plus treatment of multiple myeloma, PMID: 29091475

Soluble SLAMF7 is a predictive biomarker for elotuzumab therapy, PMID: 32398792

Elotuzumab-induced interstitial lung disease: the first case report, PMID: 29635485

Datasheet

Document Download

Research Grade Elotuzumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Elotuzumab [DHJ64001]
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