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Research Grade Golimumab (DHB94404)

Host species:Human
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHB94404

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1

Concentration

1.3mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01375

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CNTO 148, CAS: 476181-74-5

Clone ID

Golimumab

Data Image
  • Bioactivity
    Detects Human TNFa/TNF-alpha in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Golimumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Golimumab and Beta-Cell Function in Youth with New-Onset Type 1 Diabetes, PMID: 33207093

[Golimumab], PMID: 23961671

Subcutaneous golimumab induces clinical response and remission in patients with moderate-to-severe ulcerative colitis, PMID: 23735746

Golimumab, PMID: 20065639

Golimumab in the treatment of psoriatic arthritis, PMID: 30221556

Golimumab (anti-TNF monoclonal antibody): where we stand today, PMID: 33369527

Subcutaneous golimumab maintains clinical response in patients with moderate-to-severe ulcerative colitis, PMID: 23770005

Golimumab in inflammatory bowel diseases: present and future scenarios, PMID: 30206776

Golimumab: A Review in Inflammatory Arthritis, PMID: 28530020

Golimumab for the treatment of ulcerative colitis, PMID: 28472597

Golimumab for the treatment of axial spondyloarthritis, PMID: 27817204

Golimumab for rheumatoid arthritis, PMID: 20091667

Golimumab for moderately to severely active ulcerative colitis, PMID: 27498886

Patients with ankylosing spondylitis treatment by golimumab: a systematic review and meta-analysis, PMID: 32447529

Golimumab, a human antibody to tumour necrosis factor {alpha} given by monthly subcutaneous injections, in active rheumatoid arthritis despite methotrexate therapy: the GO-FORWARD Study, PMID: 19066176

A review on golimumab in the treatment of psoriatic arthritis, PMID: 28838285

[Golimumab Therapy in Ulcerative Colitis], PMID: 26907481

Golimumab in patients with active rheumatoid arthritis after treatment with tumour necrosis factor alpha inhibitors (GO-AFTER study): a multicentre, randomised, double-blind, placebo-controlled, phase III trial, PMID: 19560810

Golimumab, PMID: 19721444

Golimumab for treatment of axial spondyloarthritis, PMID: 26798943

Efficacy and safety of certolizumab pegol and golimumab in the treatment of non-infectious uveitis, PMID: 30943133

Effectiveness of golimumab in ulcerative colitis: A review of the real world evidence, PMID: 30555013

Efficacy and safety of golimumab in patients with ankylosing spondylitis: results of a randomized, double-blind, placebo-controlled, phase III trial, PMID: 18975305

Golimumab for the treatment of axial spondyloarthritis, PMID: 26523483

GO-DACT: a phase 3b randomised, double-blind, placebo-controlled trial of GOlimumab plus methotrexate (MTX) versus placebo plus MTX in improving DACTylitis in MTX-naive patients with psoriatic arthritis, PMID: 32193187

Golimumab in adolescents with Crohn's disease refractory to previous tumour necrosis factor antibody, PMID: 32781480

Golimumab, the newest TNF-α blocker, comes of age, PMID: 25602858

Golimumab for moderate to severe ulcerative colitis, PMID: 28276288

Golimumab for the treatment of psoriatic arthritis, PMID: 21609657

Golimumab and immunogenicity? 2010 and beyond, PMID: 21612149

Golimumab for rheumatoid arthritis: a systematic review, PMID: 20436075

Intravenous golimumab in rheumatoid arthritis, PMID: 24831189

Golimumab: clinical update on its use for ulcerative colitis, PMID: 25876561

Therapeutic Drug Monitoring of Golimumab in the Treatment of Ulcerative Colitis, PMID: 28374338

Golimumab and malignancies: true or false association?, PMID: 20373059

Golimumab in real-world practice in patients with ulcerative colitis: Twelve-month results, PMID: 32550760

Adverse effects of golimumab in the treatment of rheumatologic diseases, PMID: 23984970

An appraisal of golimumab in the treatment of severe, active nonradiographic axial spondyloarthritis, PMID: 27468228

Evaluation of golimumab for the treatment of patients with active rheumatoid arthritis, PMID: 26811250

Letter: golimumab efficacy in patients with Crohn's disease and concomitant severe arthritis, PMID: 32445531

Golimumab for the treatment of ankylosing spondylitis: a NICE single technology appraisal, PMID: 23580355

Golimumab improves patient-reported outcomes in daily practice of inflammatory rheumatic diseases in Germany, PMID: 32722921

Whither Type 1 Diabetes?, PMID: 33207099

Golimumab therapy of rheumatoid arthritis: an overview, PMID: 20618765

Golimumab: a tumor necrosis factor alpha inhibitor for the treatment of rheumatoid arthritis, PMID: 20118145

Golimumab: in the treatment of rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis, PMID: 19489653

[Clinical analysis of golimumab in the treatment of severe/refractory cardiovascular involvement in Behcet syndrome], PMID: 33331313

Golimumab effectiveness in biologic inadequate responding patients with rheumatoid arthritis, psoriatic arthritis and spondyloarthritis in real-life from the Italian registry GISEA, PMID: 32755721

Why golimumab in the treatment of psoriatic arthritis, ankylosing spondylitis and rheumatoid arthritis?, PMID: 25829189

Golimumab in radiographic and nonradiographic axial spondyloarthritis: a review of clinical trials, PMID: 27445459

Datasheet

Document Download

Research Grade Golimumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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