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Research Grade Certolizumab (DHB94401)

Host species:Humanized
Isotype:Fab'-IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHB94401

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

Fab'-IgG1-kappa

Clonality

Monoclonal

Target

TNF, Tumor necrosis factor ligand superfamily member 2, N-terminal fragment, ICD2, NTF, TNF-a, TNF-alpha, Tumor necrosis factor, TNFSF2, TNFA, Cachectin, ICD1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein L purified from cell culture supernatant.

Accession

P01375

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CDP870, PHA-738144, Certolizumab pegol, CAS: 428863-50-7

Clone ID

Certolizumab

Data Image
  • Bioactivity
    Detects Human TNFa/TNF-alpha in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Certolizumab
References

Certolizumab Pegol: A Review in Moderate to Severe Plaque Psoriasis, PMID: 32207094

[Certolizumab], PMID: 31208736

Certolizumab pegol for the treatment of chronic plaque psoriasis: Results through 48 weeks of a phase 3, multicenter, randomized, double-blind, etanercept- and placebo-controlled study (CIMPACT), PMID: 29660425

Certolizumab pegol for the treatment of psoriatic arthritis and plaque psoriasis, PMID: 31917928

Certolizumab pegol, PMID: 20190560

Adalimumab, etanercept, infliximab, certolizumab pegol, golimumab, tocilizumab and abatacept for the treatment of rheumatoid arthritis not previously treated with disease-modifying antirheumatic drugs and after the failure of conventional disease-modifying antirheumatic drugs only: systematic review and economic evaluation, PMID: 27140438

Certolizumab pegol for the treatment of chronic plaque psoriasis: Results through 48 weeks from 2 phase 3, multicenter, randomized, double-blinded, placebo-controlled studies (CIMPASI-1 and CIMPASI-2), PMID: 29660421

Certolizumab pegol for hidradenitis suppurativa: Case report and literature review, PMID: 33135826

Pregnancy Outcomes After Exposure to Certolizumab Pegol: Updated Results From a Pharmacovigilance Safety Database, PMID: 29623679

Lack of placental transfer of certolizumab pegol during pregnancy: results from CRIB, a prospective, postmarketing, pharmacokinetic study, PMID: 29030361

A Fifty-Two-Week, Randomized, Placebo-Controlled Trial of Certolizumab Pegol in Nonradiographic Axial Spondyloarthritis, PMID: 30848558

Maintenance of clinical remission in early axial spondyloarthritis following certolizumab pegol dose reduction, PMID: 32381562

Long-term safety of certolizumab pegol in rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis, psoriasis and Crohn's disease: a pooled analysis of 11 317 patients across clinical trials, PMID: 31245056

Certolizumab pegol for the treatment of psoriasis, PMID: 28165828

Efficacy and safety of certolizumab pegol and golimumab in the treatment of non-infectious uveitis, PMID: 30943133

Long-term efficacy of certolizumab pegol for the treatment of plaque psoriasis: 3-year results from two randomized phase III trials (CIMPASI-1 and CIMPASI-2), PMID: 32652544

Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics, PMID: 30772098

Certolizumab Pegol: A Review in Inflammatory Autoimmune Diseases, PMID: 27704400

Certolizumab for rheumatoid arthritis, PMID: 24447441

Long-term efficacy of certolizumab pegol for psoriasis, PMID: 32951203

Certolizumab pegol for treating axial spondyloarthritis, PMID: 27366922

Certolizumab pegol-induced palmoplantar pustulosis: A case report and review of the literature, PMID: 29370988

Efficacy and safety of certolizumab pegol in pregnant women with uveitis. Recommendations on the management with immunosuppressive and biologic therapies in uveitis during pregnancy, PMID: 33124565

ACG Clinical Guideline: Management of Crohn's Disease in Adults, PMID: 29610508

Sustained efficacy, safety and patient-reported outcomes of certolizumab pegol in axial spondyloarthritis: 4-year outcomes from RAPID-axSpA, PMID: 28498975

Certolizumab Pegol-Induced Heart Failure, PMID: 29232326

Certolizumab-induced facial eruption in a pregnant woman with severe Behcet's disease, PMID: 32770724

Certolizumab pegol: in rheumatoid arthritis, PMID: 19894782

Certolizumab pegol (CDP870) for rheumatoid arthritis in adults, PMID: 21328299

Certolizumab pegol: a review of its use in the management of rheumatoid arthritis, PMID: 23338540

Certolizumab pegol (CDP870) for rheumatoid arthritis in adults, PMID: 28884785

Head-to-head comparison of certolizumab pegol versus adalimumab in rheumatoid arthritis: 2-year efficacy and safety results from the randomised EXXELERATE study, PMID: 27863807

Improvement of Certolizumab Fab' properties by PASylation technology, PMID: 33116155

Certolizumab pegol for the treatment of psoriatic arthritis, PMID: 25651776

[Certolizumab pegol], PMID: 21794764

Certolizumab pegol: a review of its use in patients with axial spondyloarthritis or psoriatic arthritis, PMID: 24919863

Certolizumab pegol in axial spondyloarthritis, PMID: 24215406

Certolizumab pegol in Crohn's disease, PMID: 19180261

Certolizumab pegol: a TNF-{alpha} antagonist for the treatment of moderate-to-severe Crohn's disease, PMID: 20118143

Certolizumab pegol: in Crohn's disease, PMID: 17516714

The effect of certolizumab drug concentration and anti-drug antibodies on TNF neutralisation, PMID: 31498069

Treatment of hidradenitis suppurativa with certolizumab pegol during pregnancy, PMID: 33247833

Certolizumab pegol for the management of Crohn's disease in adults, PMID: 19695385

Certolizumab pegol for induction of remission in Crohn's disease, PMID: 31476018

Certolizumab pegol in the treatment of Crohn's disease, PMID: 23451881

Certolizumab pegol, PMID: 18670430

Patient Satisfaction with CIMZIA ® (Certolizumab Pegol) AutoClicks ® in the UK, PMID: 32124272

Profile of certolizumab and its potential in the treatment of psoriatic arthritis, PMID: 23620660

Certolizumab pegol: a new biologic targeting rheumatoid arthritis, PMID: 20979550

Certolizumab pegol in the treatment of Takayasu arteritis, PMID: 30010945

Datasheet

Document Download

Research Grade Certolizumab.pdf

 

$ 426
Product specifications
100 μg 426 1 mg 1704

Contact Information

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Research Grade Certolizumab [DHB94401]
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