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Research Grade Ranibizumab (DHD12601)

Host species:Humanized
Isotype:Fab-G1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHD12601

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

Fab-G1-kappa

Clonality

Monoclonal

Target

Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A

Concentration

1.5 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein L purified from cell culture supernatant.

Accession

P15692

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

Fab-12 variant Y0317, RhuFab, CAS: 347396-82-1

Clone ID

Ranibizumab

Data Image
  • Bioactivity
    Detects Human VEGFA in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Ranibizumab
References

Five-Year Outcomes of Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy: A Randomized Clinical Trial, PMID: 30043039

Ranibizumab for myopic choroidal neovascularization, PMID: 33003962

Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema: recent clinically relevant findings from DRCR.net Protocol T, PMID: 28837425

Ranibizumab versus laser therapy for the treatment of very low birthweight infants with retinopathy of prematurity (RAINBOW): an open-label randomised controlled trial, PMID: 31522845

Ranibizumab: A Review in Retinopathy of Prematurity, PMID: 33447937

The Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration: Results from the Randomized Phase 2 Ladder Clinical Trial, PMID: 30946888

Comparative efficacy of bevacizumab, ranibizumab, and aflibercept for treatment of macular edema secondary to retinal vein occlusion: a systematic review and network meta-analysis, PMID: 30071180

Effectiveness and safety of ranibizumab 0.5 mg in treatment-naïve patients with diabetic macular edema: Results from the real-world global LUMINOUS study, PMID: 32492069

The cost-effectiveness of bevacizumab, ranibizumab and aflibercept for the treatment of age-related macular degeneration-A cost-effectiveness analysis from a societal perspective, PMID: 29772018

Visual Field Changes Over 5 Years in Patients Treated With Panretinal Photocoagulation or Ranibizumab for Proliferative Diabetic Retinopathy, PMID: 31999300

Efficacy and Treatment Burden of Intravitreal Aflibercept Versus Intravitreal Ranibizumab Treat-and-Extend Regimens at 2 Years: Network Meta-Analysis Incorporating Individual Patient Data Meta-Regression and Matching-Adjusted Indirect Comparison, PMID: 32222903

Clinical effectiveness of ranibizumab and conbercept for neovascular age-related macular degeneration: a meta-analysis, PMID: 30464394

Ranibizumab for age-related macular degeneration, PMID: 22309606

Ranibizumab and digital ischemia, PMID: 29425544

Assessing the role of ranibizumab in improving the outcome of glaucoma filtering surgery and neovascular glaucoma, PMID: 29781319

Ranibizumab and aflibercept for the treatment of wet age-related macular degeneration, PMID: 26076760

Switching between ranibizumab and aflibercept for the treatment of neovascular age-related macular degeneration, PMID: 29476754

Efficacy and Safety of a Proposed Ranibizumab Biosimilar Product vs a Reference Ranibizumab Product for Patients With Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial, PMID: 33211076

Ranibizumab Population Pharmacokinetics and Free VEGF Pharmacodynamics in Preterm Infants With Retinopathy of Prematurity in the RAINBOW Trial, PMID: 32855889

[Ranibizumab and aflibercept for diabetic macular edema-retrospective study with real-life data after 12 months], PMID: 31705192

Intravitreal ranibizumab and dexamethasone implant injections as primary treatment of diabetic macular edema: simultaneously double protocol, PMID: 32398852

Real-World Effectiveness and Real-World Cost-Effectiveness of Intravitreal Aflibercept and Intravitreal Ranibizumab in Neovascular Age-Related Macular Degeneration: Systematic Review and Meta-Analysis of Real-World Studies, PMID: 31728825

Intraocular Pharmacokinetics of 10-fold Intravitreal Ranibizumab Injection Dose in Rabbits, PMID: 32818095

Ranibizumab plus fufang xueshuantong capsule versus ranibizumab alone for exudative age-related macular degeneration, PMID: 32962487

Ranibizumab for the treatment of wet AMD: a summary of real-world studies, PMID: 26634711

Intravitreal Ranibizumab Injection for the Treatment of Retinopathy of Prematurity, PMID: 30995663

Ranibizumab treatment patterns in prior ranibizumab-treated neovascular age-related macular degeneration patients: Real-world outcomes from the LUMINOUS study, PMID: 33378369

Therapeutic Monoclonal Antibodies and Fragments: Ranibizumab, PMID: 26501149

Photodynamic therapy in combination with ranibizumab versus ranibizumab monotherapy for wet age-related macular degeneration: A systematic review and meta-analysis, PMID: 29753123

Renal Biomarkers for Treatment Effect of Ranibizumab for Diabetic Macular Edema, PMID: 32908935

Ranibizumab in the Treatment of Diabetic Macular Edema: A Review of the Current Status, Unmet Needs, and Emerging Challenges, PMID: 28484955

Real-world effectiveness and safety of ranibizumab for the treatment of myopic choroidal neovascularization: Results from the LUMINOUS study, PMID: 31961888

Intravitreal Ranibizumab for the Treatment of Visual Impairment Due to Choroidal Neovascularization Associated with Rare Diseases: Cost-Effectiveness in the UK, PMID: 30726549

Intravitreal ranibizumab reduced ocular blood flow and aqueous cytokine levels and improved retinal morphology in patients with diabetic macular edema, PMID: 33303870

Post-Ranibizumab injection endophthalmitis in aggressive posterior retinopathy of prematurity, PMID: 31124535

Ranibizumab for Macular Edema Secondary to Central and Branch Retinal Vein Occlusion in Patients Younger Than 50 Years of Age, PMID: 32685489

Aflibercept for neovascular age-related macular degeneration, PMID: 26857947

Ranibizumab port delivery system (RPDS): realising long awaited dream of prolonged VEGF suppression, PMID: 31165769

Switching from ranibizumab and aflibercept to bevacizumab therapy in neovascular age-related macular degeneration patients, PMID: 32375502

Cost-Minimization Analysis of Ranibizumab Versus Aflibercept for Treating Saudi Patients With Visual Impairment Owing to Age-Related Macular Degeneration or Diabetic Macular Edema, PMID: 32247191

Biomechanical properties of the cornea following intravitreal ranibizumab injection, PMID: 33165643

Therapeutic effects of ranibizumab in patients with polypoidal choroidal vasculopathy, PMID: 31324161

Cardiovascular risk in patients receiving ranibizumab for exudative age-related macular degeneration: a nationwide self-controlled case-series study, PMID: 32522792

Outcomes and costs of Ranibizumab and Aflibercept treatment in a health-service research context, PMID: 29486762

Evaluation of ranibizumab and aflibercept for the treatment of diabetic macular edema in daily clinical practice, PMID: 31644594

Ranibizumab in macular oedema secondary to branch retinal vein occlusion - 24 months of treatment, PMID: 32397721

Use of Bevacizumab and Ranibizumab for Wet Age-Related Macular Degeneration: Influence of CATT Results and Introduction of Aflibercept, PMID: 31100217

Ranibizumab for the treatment of choroidal neovascularization due to cause other than age related macular degeneration, PMID: 31779462

Real-world outcomes with ranibizumab in branch retinal vein occlusion: The prospective, global, LUMINOUS study, PMID: 32555630

Effect of intravitreal ranibizumab pretreatment on vitrectomy in young patients with proliferative diabetic retinopathy, PMID: 32005066

Datasheet

Document Download

Research Grade Ranibizumab.pdf

 

$ 426
Product specifications
100 μg 426 1 mg 1704

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Research Grade Ranibizumab [DHD12601]
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