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Research Grade Bevacizumab (DHD12602)

Host species:Humanized
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHD12602

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Vascular endothelial growth factor A, VPF, VEGFA, VEGF, Vascular permeability factor, VEGF-A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P15692

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

12-IgG1, F(ab)-12 IgG1, Fab-12 IgG1, rhuMAb-VEGF, ABP 215, CAS: 216974-75-3

Clone ID

Bevacizumab

Data Image
  • Bioactivity
    Detects Human VEGF165 in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Bevacizumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Bevacizumab (Avastin®) in cancer treatment: A review of 15 years of clinical experience and future outlook, PMID: 32335505

Bevacizumab-induced hypertension: Clinical presentation and molecular understanding, PMID: 28882537

The role of bevacizumab in the treatment of glioblastoma, PMID: 28527008

Bevacizumab in Colorectal Cancer: Current Role in Treatment and the Potential of Biosimilars, PMID: 28801849

Bevacizumab in advanced lung cancer: state of the art, PMID: 28812378

Bevacizumab in ovarian cancer: A critical review of phase III studies, PMID: 27852039

Bevacizumab with or after chemotherapy for platinum-resistant recurrent ovarian cancer: exploratory analyses of the AURELIA trial, PMID: 28481967

Bevacizumab in Cervical Cancer: 5 Years After, PMID: 30119082

The role of bevacizumab on tumour angiogenesis and in the management of gynaecological cancers: A review, PMID: 29710531

[Bevacizumab], PMID: 30634827

Medical and developmental outcomes of bevacizumab versus laser for retinopathy of prematurity, PMID: 29223789

Bevacizumab treatment of meningeal melanoma metastases, PMID: 31915016

The use of bevacizumab in pediatric retinal and choroidal disease: A review, PMID: 30757919

Introduction by the Guest Editors: Bevacizumab, PMID: 30119078

Bevacizumab dose adjustment to improve clinical outcomes of glioblastoma, PMID: 32564774

[Progress of Bevacizumab in the Front-line Treatment of Advanced Non-small Cell Lung Cancer], PMID: 32702797

Commentary: Single-use bevacizumab: The final solution?, PMID: 32461440

Systemic bevacizumab for recurrent respiratory papillomatosis, PMID: 32906078

Perforating folliculitis triggered by bevacizumab administration, PMID: 32463526

Vascular effect of bevacizumab: is it too early to draw conclusions?, PMID: 31913945

Bevacizumab-induced intestinal perforation in a patient with inoperable breast cancer: a case report and review of the literature, PMID: 29580267

Critical appraisal of bevacizumab in the treatment of ovarian cancer, PMID: 25960638

Monitoring antiangiogenesis of bevacizumab in zebrafish, PMID: 30122900

Correlation Between Bevacizumab Exposure and Survival in Patients with Metastatic Colorectal Cancer, PMID: 32272489

Efficacy and Toxicity of Addition of Bevacizumab to Chemotherapy in Patients with Metastatic Colorectal Cancer, PMID: 30663563

Off-label infusion of biosimilar bevacizumab: A provincial experience, PMID: 32727322

Bevacizumab in progressive disseminated atypical choroid plexus papilloma in adults, PMID: 32249894

Use of bevacizumab in recurrent glioblastoma, PMID: 25906439

Systemic Bevacizumab (Avastin) for Juvenile-Onset Recurrent Respiratory Papillomatosis: A Systematic Review, PMID: 32959914

Revisiting the Role of Bevacizumab in the Treatment of Breast Cancer, PMID: 29526256

The role of selenium in bevacizumab induced cardiotoxicity, PMID: 30793617

In vivo efficacy of bevacizumab-loaded albumin nanoparticles in the treatment of colorectal cancer, PMID: 32040774

Microneedle-Mediated Transdermal Delivery of Bevacizumab, PMID: 29996645

Impaired wound healing secondary to bevacizumab, PMID: 31111622

Intravenous Bevacizumab in Hereditary Hemorrhagic Telangiectasia-Related Bleeding and High-Output Cardiac Failure: Significant Inter-Individual Variability in the Need for Maintenance Therapy, PMID: 32753135

[Application of Bevacizumab in Non-small Cell Lung Cancer], PMID: 28442017

Bevacizumab: a new way of doing business. Part 2, PMID: 30482906

Practical management of bevacizumab-related toxicities in glioblastoma, PMID: 25568148

Correlation Between Bevacizumab Exposure and Survival Does Not Necessarily Imply Causality, PMID: 33044752

Systemic Bevacizumab for Treatment of Respiratory Papillomatosis: International Consensus Statement, PMID: 33405268

Intravitreal bevacizumab for retinopathy of prematurity: Considerations for informed consent, PMID: 26651298

Intralesional injection of bevacizumab versus triamcinolone acetonide in infantile hemangioma, PMID: 30835573

The Benefits and Side Effects of Bevacizumab for the Treatment of Recurrent Ovarian Cancer, PMID: 27138763

The safety and efficacy of bevacizumab in the treatment of patients with recurrent or metastatic cervical cancer, PMID: 27748633

Clinical use of Bevacizumab in treating refractory glaucoma, PMID: 25914729

Sequential Treatment with Bevacizumab and Aflibercept for Metastatic Colorectal Cancer in Real-World Clinical Practice, PMID: 32052341

Gravity influences bevacizumab distribution in an undisturbed balanced salt solution in vitro, PMID: 31584989

Bevacizumab improves survival in metastatic colorectal cancer patients with primary tumor resection: A meta-analysis, PMID: 31889159

[Off-label use of intravitreal bevacizumab for severe retinopathy of prematurity], PMID: 25459682

Efficacy of topical bevacizumab 0.05% eye drops in dry eye disease: A double-masked, randomized trial, PMID: 32502179

Datasheet

Document Download

Research Grade Bevacizumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Bevacizumab [DHD12602]
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