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Research Grade Alemtuzumab (DHD95101)

Host species:Humanized
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHD95101

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

Human epididymis-specific protein 5, CDW52, CAMPATH-1 antigen, Cambridge pathology 1 antigen, He5, HE5, Epididymal secretory protein E5, CD52, CDw52

Concentration

1.03 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P31358

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

Campath-1H, LDP-03, CAS: 216503-57-0

Clone ID

Alemtuzumab

Data Image
  • SDS-PAGE
    SDS PAGE for Alemtuzumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Alemtuzumab for the treatment of multiple sclerosis, PMID: 29309202

Alemtuzumab as Treatment for Multiple Sclerosis, PMID: 29500306

[Alemtuzumab therapy 2017], PMID: 29870645

Clinical pharmacology of alemtuzumab, an anti-CD52 immunomodulator, in multiple sclerosis, PMID: 30144037

The Meaning of Immune Reconstitution after Alemtuzumab Therapy in Multiple Sclerosis, PMID: 32503344

Alemtuzumab for Multiple Sclerosis, PMID: 27485945

A case of anaphylaxis to alemtuzumab, PMID: 30715557

Acquired haemophilia A after alemtuzumab therapy, PMID: 32700327

New cases of vasculitis after alemtuzumab, PMID: 32081067

Principles of alemtuzumab immunoablation in hematopoietic cell transplantation for non-malignant diseases in children: A review, PMID: 29352515

Alemtuzumab and prescription medication use in the MS population, PMID: 32403069

Alemtuzumab for multiple sclerosis, PMID: 27082500

Alemtuzumab therapy for multiple sclerosis, PMID: 23184314

Alemtuzumab, PMID: 18165760

Alemtuzumab Use in Clinical Practice: Recommendations from European Multiple Sclerosis Experts, PMID: 27882532

Alemtuzumab-associated diffuse alveolar damage - a case report, PMID: 32967641

Alemtuzumab in the treatment of multiple sclerosis: patient selection and special considerations, PMID: 27799738

Alemtuzumab therapy changes immunoglobulin levels in peripheral blood and CSF, PMID: 31826986

Anemia and sarcoidosis following treatment with alemtuzumab, PMID: 32979730

Alemtuzumab: Rare serious adverse events of a high-efficacy drug, PMID: 32298205

Alemtuzumab Induction Versus Conventional Immunosuppression in Heart Transplant Recipients, PMID: 31035777

Sarcoidosis following alemtuzumab treatment: Autoimmunity mediated by T cells and interferon-γ, PMID: 30307361

Alemtuzumab versus interferon beta 1a for relapsing-remitting multiple sclerosis, PMID: 29178444

Clinical observation during alemtuzumab administration, PMID: 32172992

Intracerebral haemorrhage during alemtuzumab administration, PMID: 30777657

Comparison of Alemtuzumab and Anti-thymocyte Globulin Treatment for Acute Kidney Allograft Rejection, PMID: 32719676

Alemtuzumab as rescue therapy in case of multiple sclerosis rebound following Natalizumab break: Clinical case and literature review, PMID: 30851640

Alemtuzumab for cytolytic induction of immunosuppression in heart transplant recipients, PMID: 23187050

A review on the treatment of sporadic inclusion body myositis with Bimagrumab and Alemtuzumab, PMID: 30238817

Alemtuzumab outcomes by age: Post hoc analysis from the randomized CARE-MS studies over 8 years, PMID: 33476880

Alemtuzumab induction therapy in kidney transplantation: a systematic review and meta-analysis, PMID: 22660659

Immune thrombocytopenia in alemtuzumab-treated MS patients: Incidence, detection, and management, PMID: 30785358

Listeria infection after treatment with alemtuzumab: a case report and literature review. Would antibiotic prophylaxis be considered?, PMID: 32487792

Alemtuzumab: the advantages and challenges of a novel therapy in MS, PMID: 24920854

Alemtuzumab to be restricted pending review, says EMA, PMID: 31034363

Efficacy and safety of alemtuzumab in Korean multiple sclerosis patients, PMID: 30849681

Pharmacokinetics of alemtuzumab in pediatric patients undergoing ex vivo T-cell-depleted haploidentical hematopoietic cell transplantation, PMID: 33037919

B and T cell prolymphocytic leukaemia, PMID: 31585622

Alemtuzumab-induced simultaneous onset of autoimmune haemolytic anaemia, alveolar haemorrhage, nephropathy, and stroke: A case report, PMID: 32446212

Emerging safety issues in alemtuzumab-treated MS patients, PMID: 31368417

Alemtuzumab as a Therapy for Chronic Lung Allograft Dysfunction in Lung Transplant Recipients With Short Telomeres, PMID: 32547557

Timing of Alemtuzumab With Respect to Day of Bone Marrow Infusion and its Effects Upon Engraftment and Graft-Versus-Host Disease in Patients With Sickle Cell Disease: A Single-Institutional Study, PMID: 32890079

Risk of opportunistic infections in patients treated with alemtuzumab for multiple sclerosis, PMID: 29848085

Kidney transplantation using alemtuzumab, belatacept, and sirolimus: Five-year follow-up, PMID: 32515087

Alemtuzumab depletion failure can occur in multiple sclerosis, PMID: 29247512

Alemtuzumab (Campath-1H) experience in kidney transplantation what we have learned; current practices; and scope for the future?, PMID: 26536426

The role of alemtuzumab in nonmyeloablative hematopoietic transplantation, PMID: 16720202

Monitoring and management of autoimmunity in multiple sclerosis patients treated with alemtuzumab: practical recommendations, PMID: 29525836

Alemtuzumab in Multiple Sclerosis: Short- and Long-Term Effects of Immunodepletion on the Peripheral Treg Compartment, PMID: 31214176

Overview of alemtuzumab therapy for the treatment of T-cell lymphomas, PMID: 21980956

Datasheet

Document Download

Research Grade Alemtuzumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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For research use only. Not for human or drug use.

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Research Grade Alemtuzumab [DHD95101]
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