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Research Grade Palivizumab

Catalog #:   DVV02801 Specific References (101) DATASHEET
Host species: Humanized
Isotype: IgG1, kappa
Applications: Research Grade Biosimilar
Expression system: Mammalian Cells
Overview

Catalog No.

DVV02801

Expression system

Mammalian Cells

Species reactivity

HRSV-A

Host species

Humanized

Isotype

IgG1, kappa

Clonality

Monoclonal

Applications

Research Grade Biosimilar

Target

F, Fusion glycoprotein F0, Fusion glycoprotein F2, p27, Intervening segment, Pep27, Peptide 27, Fusion glycoprotein F1

Concentration

2.44 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P03420

Form

Liquid

Storage buffer

3% Sucrose, 50mM L-Histidine, 50mM L-Arginine, pH 6.0

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

MEDI-493, CAS: 188039-54-5

Clone ID

Palivizumab

Note

For research use only. Not suitable for clinical or therapeutic use.

Data Image
  • Bioactivity
    Detects F/Fusion glycoprotein F0 in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Palivizumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
  • Bioactivity
    Detects HRSV-A2 Pre-F/Fusion glycoprotein F0 Protein in indirect ELISA.
  • Bioactivity
    Detects HRSV Post-F/Fusion glycoprotein F0 Protein in indirect ELISA.
  • Bioactivity
    Detects HRSV F/Fusion glycoprotein F0 Protein in indirect ELISA.
  • Bioactivity
    Figure S5. Binding of a panel of antibodies to DS1, DS2, and PF proteins both pre- and post-conjugation to PC7A/CpG. Antibody binding to DS1, DS2, and PF proteins before (A, C, and E) and after (B, D, and F) conjugation to PC7A/CpG was determined via indirect ELISA. The reactivities of PV2, MPE8, 101F, hRSV90, and 8897 were expressed as EC50 values corresponding to the concentration at which the half-maximum signal was obtained via ELISA, which was based on the optical density at 450 nm.
    Data sourced from citation (PMID: DOI: 10.1002/adfm.202510925)
References

A Self-Assembled RSV-DS2 Based Nanovaccine Elicits a Strong Immune Response Against Respiratory Syncytial Virus Infection. [DVV02801]

[Not Available]., PMID:39586603

[Not Available]., PMID:39586606

The Impact of Palivizumab for Respiratory Syncytial Virus Prophylaxis on Preschool Childhood Asthma., PMID:39591172

Approach to prevention of respiratory syncytial virus disease in infants by passive immunization., PMID:39638376

Trends in endemic of respiratory syncytial virus infection during COVID-19 pandemic and difficulty in obtaining optimal timing of palivizumab prophylaxis., PMID:39667557

Risks and prevention of severe respiratory syncytial virus infection among infants and children with pulmonary hypoplasia, airway stenosis, congenital esophageal atresia, inborn errors of metabolism, or neuromuscular diseases in Japan., PMID:39674346

Use of the moving epidemic method to guide the launch of palivizumab immunization campaigns for respiratory syncytial virus in Québec, Canada., PMID:39702848

Amino acid substitutions in the fusion protein of respiratory syncytial virus in Fukushima, Japan during 2008-2023 and their effects., PMID:39719011

The molecular epidemiology of respiratory syncytial virus in Ontario, Canada from 2022-2024 using a custom whole genome sequencing assay and analytics package., PMID:39721564

Evolving Strategies for Respiratory Syncytial Virus (RSV): A Review Article of Preventive Agents and Vaccines for RSV., PMID:39744803

[Benefits of home-based administration of palivizumab in high-risk groups]., PMID:39760599

Respiratory Syncytial Virus: A WAidid Consensus Document on New Preventive Options., PMID:39771979

Increased Respiratory Syncytial Virus-Associated Hospitalizations and Ambulatory Visits in Very Preterm Infants in the First Year of Life following Discontinuation of Access to Palivizumab., PMID:39788540

The recent landscape of RSV vaccine research., PMID:39802673

Inpatient service utilization amongst infants diagnosed with Respiratory Syncytial Virus infection (RSV) in the United States., PMID:39804848

Investigating the metabolic load of monoclonal antibody production conveyed to an inducible CHO cell line using a transfer-rate online monitoring system., PMID:39828082

An engineered palivizumab IgG2 subclass for synthetic gp130 and fas-mediated signaling., PMID:39828098

Efficacy of a standardized regional palivizumab administration protocol based on epidemic prediction for the following season., PMID:39892510

Economic and clinical burden associated with respiratory syncytial virus and impact of universal immunization with nirsevimab in Italy., PMID:39897385

Early Experience on Universal Prophylaxis in Infants against Respiratory Syncytial Virus: Facts and Expectations., PMID:39900111

Learn from international recommendations and experiences of countries that have successfully implemented monoclonal antibody prophylaxis for prevention of RSV infection., PMID:39905524

Healthcare utilization during acute medically attended episodes of respiratory syncytial virus-related lower respiratory tract infection among infants in the United States., PMID:39928629

Practice recommendations for respiratory syncytial virus prophylaxis among children in Hong Kong., PMID:39957107

Cost-Effectiveness Analysis of Nirsevimab for Preventing Respiratory Syncytial Virus-Related Lower Respiratory Tract Disease in Dutch Infants: An Analysis Including All-Infant Protection., PMID:39976899

Cost-effectiveness of nirsevimab and maternal RSVpreF for preventing respiratory syncytial virus disease in infants across Canada., PMID:39984979

Incidence of and Risk Factors for Subsequent Lower Respiratory Tract Infection Following an Infant RSV Hospitalization., PMID:40003285

Knowledge and Attitudes Regarding Respiratory Syncytial Virus (RSV) Prevention: A Systematic Review., PMID:40006706

Adherence to Palivizumab for Respiratory Syncytial Virus Prophylaxis in Romanian Infants., PMID:40006718

Cost-effectiveness of wastewater and environmental monitoring of respiratory syncytial virus to guide universal infant immunoprophylaxis in Canada., PMID:40019444

Recommendation for immune prophylaxis of respiratory syncytial virus infection in children., PMID:40032543

Respiratory Syncytial Virus Burden in Premature Infants: The Role of Season With and Without RSV Immunoprophylaxis in a Multicenter Study., PMID:40042149

Twenty-five years of palivizumab: a global historic review of its impact on the burden of respiratory syncytial virus disease in children., PMID:40111069

A practical guidance on the prevention and treatment of childhood respiratory syncytial virus infection in Kurdistan., PMID:40151184

Cost-Effectiveness and Public Health Impact of Universal Prophylaxis with Nirsevimab Against Respiratory Syncytial Virus (RSV) Infections in all Infants in Japan., PMID:40153134

RSV Prevention Strategies in Korean Children: A Review of Current Approaches and Emerging Options., PMID:40183652

Health economic evaluation of implementing a universal immunization program with nirsevimab compared to standard of care for the prevention of respiratory syncytial virus disease in Canadian infants., PMID:40186452

Palivizumab coverage rates among moderate-to-late preterm infants in Korea: a nationwide cross-sectional study., PMID:40211817

Optimizing risk factors to guide COST-effective use of palivizumab in KOREAN infants., PMID:40214194

Summary of the National Advisory Committee on Immunization (NACI) Statement on the Prevention of Respiratory Syncytial Virus (RSV) in Infants., PMID:40241712

Palivizumab for the Prophylaxis of Respiratory Syncytial Virus Disease: Expert Opinion and Recommendations for the Gulf Cooperation Council Region., PMID:40248327

Human iPS cell-derived respiratory organoids as a model for respiratory syncytial virus infection., PMID:40262853

Cost-Effectiveness Analysis of Nirsevimab for the Prevention of Respiratory Syncytial Virus among Italian Infants., PMID:40317387

Knowledge, attitudes, and practices of Croatian pediatricians and pediatrics residents about RSV infection., PMID:40328920

Direct Out-of-Pocket Costs of Nirsevimab vs. Palivizumab during the First Respiratory Syncytial Virus Season: A Comparative Analysis., PMID:40343422

The influence of respiratory syncytial virus immunoprophylaxis on allergic sensitisation in children with respiratory allergy., PMID:40360322

Challenges in the prophylaxis of severe respiratory syncytial virus infections., PMID:40373821

Respiratory syncytial virus preventives for children in Australia: current landscape and future directions., PMID:40413643

The potential public health impact of new immunization strategies for the prevention of RSV in children in Panama., PMID:40458968

Turkish pediatricians' knowledge, attitudes, and awareness of respiratory syncytial virus (RSV) infection and immunization strategies: a cross-sectional study., PMID:40466672

Respiratory Syncytial Virus: A Narrative Review of Updates and Recent Advances in Epidemiology, Pathogenesis, Diagnosis, Management and Prevention., PMID:40507642

Palivizumab Prophylaxis Against Respiratory Syncytial Virus Infection in Children with Immunocompromised Conditions or Down Syndrome: A Multicenter, Post-Marketing Surveillance in Japan, PMID: 28895096

The cost effectiveness of palivizumab: a systematic review of the evidence, PMID: 20653398

Palivizumab prophylaxis of respiratory syncytial virus infection in high-risk infants, PMID: 12410864

Role of viral infections in the development and exacerbation of asthma in children, PMID: 28987219

Palivizumab and the prevention of respiratory syncytial virus illness in pediatric patients with congenital heart disease, PMID: 17727335

Revised recommendations concerning palivizumab prophylaxis for respiratory syncytial virus (RSV), PMID: 26670908

Restricted Palivizumab Recommendations and the Impact on RSV Hospitalizations among Infants Born at > 29 Weeks of Gestational Age: An Italian Multicenter Study, PMID: 31238365

Palivizumab in the prophylaxis of respiratory syncytial virus infection, PMID: 16207163

Palivizumab use in infants with Down syndrome-report from the German Synagis™ Registry 2009-2016, PMID: 29651734

A review of cost-effectiveness of palivizumab for respiratory syncytial virus, PMID: 23140255

Palivizumab prophylaxis, respiratory syncytial virus and subsequent development of asthma, PMID: 29795072

Palivizumab administration in preterm infants in France: EPIPAGE-2 cohort study, PMID: 29395887

Palivizumab and prevention of childhood respiratory syncytial viral infection: protocol for a systematic review and meta-analysis of breakthrough infections, PMID: 31340973

Bronchiolitis: an update on management and prophylaxis, PMID: 31059347

The potential impact of palivizumab on pediatric airway reconstruction, PMID: 16360816

Treatment of respiratory syncytial virus with palivizumab: a systematic review, PMID: 21080142

Systematic Review of the Safety and Efficacy of Palivizumab among Infants and Young Children with Cystic Fibrosis, PMID: 28423192

Optimizing Lung Function in Survivors of Preterm Birth: Palivizumab Is Not the Answer, PMID: 32768062

Reducing Palivizumab Dose Requirements Through Rational Dose Regimen Design, PMID: 30426719

A review of palivizumab and emerging therapies for respiratory syncytial virus, PMID: 21831008

Effectiveness of Palivizumab against Respiratory Syncytial Virus: Cohort and Case Series Analysis, PMID: 31378522

Consensus conference on the appropriateness of palivizumab prophylaxis in respiratory syncytial virus disease, PMID: 27618642

Is palivizumab effective as a prophylaxis of respiratory syncytial virus infections in cystic fibrosis patients? A meta-analysis, PMID: 24231153

Palivizumab prophylaxis in 'late preterm' newborns, PMID: 20695756

Administration of Palivizumab in the NICU, PMID: 27164941

Palivizumab for respiratory syncytial virus prophylaxis, PMID: 10690084

Palivizumab Following Extremely Premature Birth Does Not Affect Pulmonary Outcomes in Adolescence, PMID: 32298728

Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis, PMID: 20166098

Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis, PMID: 27439110

Universal palivizumab prophylaxis for children with Down syndrome in Japan: analysis with interrupted time-series, PMID: 32961094

Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis, PMID: 24851825

Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis, PMID: 22336832

Neutralizing epitopes of RSV and palivizumab resistance in Japan, PMID: 28867684

Initial Palivizumab Dose Administration in Outpatient Clinic After Hospital Discharge, PMID: 29570593

Respiratory Syncytial Virus Bronchiolitis in Children, PMID: 28084708

Palivizumab for prophylaxis against respiratory syncytial virus infection in children with cystic fibrosis, PMID: 23737087

Palivizumab Prophylaxis and Recurrent Wheezing, PMID: 29019698

Adherence and outcomes: a systematic review of palivizumab utilization, PMID: 29130355

Palivizumab's real-world effectiveness: a population-based study in Ontario, Canada, 1993-2017, PMID: 32859612

Palivizumab: an overview, PMID: 10707171

Utilization and efficacy of palivizumab for children with Down syndrome, PMID: 31961027

Palivizumab prophylaxis in preterm infants, PMID: 28219614

Palivizumab and Long-term Outcomes in Cystic Fibrosis, PMID: 31239289

Improving the prescribing of palivizumab, PMID: 29863814

Palivizumab: where to from here?, PMID: 19063700

Product review on the monoclonal antibody palivizumab for prevention of respiratory syncytial virus infection, PMID: 28605249

Palivizumab, PMID: 10473022

Palivizumab, a humanized respiratory syncytial virus monoclonal antibody, reduces hospitalization from respiratory syncytial virus infection in high-risk infants. The IMpact-RSV Study Group, PMID: 9738173

Cost-effectiveness of Palivizumab for Respiratory Syncytial Virus: A Systematic Review, PMID: 31040196

Expert consensus on palivizumab use for respiratory syncytial virus in developed countries, PMID: 31060948

Datasheet

Document Download

Research Grade Palivizumab.pdf

 

$ 280
Product specifications
1 mg 280 5 mg 840 25 mg 2350

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Research Grade Palivizumab [DVV02801]
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