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Research Grade Daclizumab (DHB95801)

Host species:Humanized
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHB95801

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Humanized

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

IL2-RA, IL-2R subunit alpha, TAC antigen, IL-2-RA, p55, IL2RA, IL-2 receptor subunit alpha, Interleukin-2 receptor subunit alpha, CD25

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01589

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BIIB019, DAC HYP, CAS: 152923-56-3

Clone ID

Daclizumab

Data Image
  • Bioactivity
    Detects Human CD25/IL2RA in indirect ELISAs.
  • SDS-PAGE
    SDS PAGE for Daclizumab
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Daclizumab Therapy for Multiple Sclerosis, PMID: 29661806

Daclizumab in multiple sclerosis, PMID: 29645071

▼ Daclizumab for MS, PMID: 28183723

Daclizumab, PMID: 17916050

Daclizumab: A Review in Relapsing Multiple Sclerosis, PMID: 28211007

Daclizumab for the treatment of multiple sclerosis, PMID: 28849702

Daclizumab for the treatment of adults with relapsing forms of multiple sclerosis, PMID: 28803486

Daclizumab therapy for multiple sclerosis, PMID: 23055048

Daclizumab-induced encephalitis in multiple sclerosis, PMID: 31549941

Daclizumab: Development, Clinical Trials, and Practical Aspects of Use in Multiple Sclerosis, PMID: 28707278

Daclizumab and its use in multiple sclerosis treatment, PMID: 28387383

Daclizumab for relapsing remitting multiple sclerosis, PMID: 22513956

Pharmacokinetic drug evaluation of daclizumab for the treatment of relapsing-remitting multiple sclerosis, PMID: 29363337

Daclizumab for relapsing remitting multiple sclerosis, PMID: 24363032

Daclizumab for relapsing remitting multiple sclerosis, PMID: 20556791

Daclizumab (anti-CD25) in multiple sclerosis, PMID: 24768797

Daclizumab: a review of its use in the management of organ transplantation, PMID: 11707149

Daclizumab: a potential asthma therapy?, PMID: 20804450

Daclizumab (anti-Tac, Zenapax) in the treatment of leukemia/lymphoma, PMID: 17530023

Daclizumab: a review of its use in the prevention of acute rejection in renal transplant recipients, PMID: 10651389

Modulation of IL-2Rα with daclizumab for treatment of multiple sclerosis, PMID: 23732529

Characterization of the Impact of Daclizumab Beta on Circulating Natural Killer Cells by Mass Cytometry, PMID: 32391016

Immune-mediated encephalitis with daclizumab: The final nail, PMID: 30073908

End of the road for daclizumab in multiple sclerosis, PMID: 29565004

Severe meningo-/encephalitis after daclizumab therapy for multiple sclerosis, PMID: 30657420

A critical appraisal of daclizumab use as emerging therapy in multiple sclerosis, PMID: 25826609

Review of daclizumab and its therapeutic potential in the treatment of relapsing-remitting multiple sclerosis, PMID: 24143075

Long-term safety and efficacy of daclizumab beta in relapsing-remitting multiple sclerosis: 6-year results from the SELECTED open-label extension study, PMID: 32451615

Anti-CD25 (daclizumab) monoclonal antibody therapy in relapsing-remitting multiple sclerosis, PMID: 22284868

Daclizumab for the treatment of relapsing-remitting multiple sclerosis, PMID: 28286970

Daclizumab to prevent rejection after cardiac transplantation, PMID: 15987919

90 Y-Daclizumab (Anti-CD25), High-Dose Carmustine, Etoposide, Cytarabine, and Melphalan Chemotherapy and Autologous Hematopoietic Stem Cell Transplant Yielded Sustained Complete Remissions in 4 Patients with Recurrent Hodgkin's Lymphoma, PMID: 32275165

Daclizumab HYP versus Interferon Beta-1a in Relapsing Multiple Sclerosis, PMID: 26444729

A fatal case of daclizumab-induced liver failure in a patient with MS, PMID: 30800722

Daclizumab (Zinbryta) for multiple sclerosis, PMID: 27603962

The development of sarcoidosis in patients receiving daclizumab: A case series from multiple clinical trials, PMID: 30885425

Disease modifying therapies for relapsing multiple sclerosis, PMID: 27549763

Anti-interleukin-2 receptor antibodies: basiliximab and daclizumab, PMID: 11522853

Daclizumab use in patients with pediatric multiple sclerosis, PMID: 22232346

Rash developing after cessation of Daclizumab for relapsing remitting MS; a case series, PMID: 31421627

Daclizumab-induced adverse events in multiple organ systems in multiple sclerosis, PMID: 24532277

Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECT): a randomised, double-blind, placebo-controlled trial, PMID: 23562009

Severe cutaneous adverse event in a daclizumab-treated multiple sclerosis patient, PMID: 31228714

Delayed onset hypophysitis after therapy with daclizumab for multiple sclerosis - A report of two cases, PMID: 33387829

Daclizumab induction therapy in liver transplant recipients with renal insufficiency, PMID: 20659283

Daclizumab for treatment of birdshot chorioretinopathy, PMID: 18268208

[Off-label use of biologic agents in the treatment of dermatosis, part 2: etanercept, efalizumab, alefacept, rituximab, daclizumab, basiliximab, omalizumab, and cetuximab], PMID: 18206084

Spotlight on anti-CD25: daclizumab in MS, PMID: 18808743

Daclizumab high-yield process in relapsing-remitting multiple sclerosis (SELECTION): a multicentre, randomised, double-blind extension trial, PMID: 24656609

A case of immune-mediated encephalitis related to daclizumab therapy, PMID: 30073905

Datasheet

Document Download

Research Grade Daclizumab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

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Research Grade Daclizumab [DHB95801]
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