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Research Grade Basiliximab (DHB95802)

Host species:Chimeric
Isotype:IgG1-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHB95802

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Chimeric

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

IL2-RA, IL-2R subunit alpha, TAC antigen, IL-2-RA, p55, IL2RA, IL-2 receptor subunit alpha, Interleukin-2 receptor subunit alpha, CD25

Concentration

1.09mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P01589

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

CHI621, CHI-621 / SDZ-CHI-621, CAS: 179045-86-4, CAS: 2417483-64-6, DHB95812

Clone ID

Basiliximab

Data Image
  • SDS-PAGE
    SDS PAGE for Basiliximab
  • Bioactivity
    Detects CD25/IL2RA in indirect ELISAs.
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Basiliximab, PMID: 10188761

Rabbit-ATG or basiliximab induction for rapid steroid withdrawal after renal transplantation (Harmony): an open-label, multicentre, randomised controlled trial, PMID: 27871759

Basiliximab: a review of its use as induction therapy in renal transplantation, PMID: 14664658

Induction therapy of basiliximab versus antithymocyte globulin in renal allograft: a systematic review and meta-analysis, PMID: 28986715

A benefit-risk assessment of basiliximab in renal transplantation, PMID: 14717621

Efficacy and safety of basiliximab in kidney transplantation, PMID: 15934854

Does basiliximab induction trigger lifethreatening ARDS and shock in young patients after kidney transplantation?, PMID: 24131675

Low-dose Thymoglobulin vs Basiliximab Induction Therapy in Low-Risk Living Related Kidney Transplant Recipients: A Prospective Randomized Trial, PMID: 32178925

Basiliximab, mechanism of action and pharmacological properties, PMID: 15648237

Biologic therapy in the idiopathic inflammatory myopathies, PMID: 31680207

Efficacy and safety of basiliximab as initial immunosuppression in liver transplantation: A single center study, PMID: 32768592

Basiliximab as Treatment for Steroid-Refractory Acute Graft-versus-Host Disease in Pediatric Patients after Haploidentical Hematopoietic Stem Cell Transplantation, PMID: 31704470

Pharmacokinetics of Basiliximab for the Prevention of Graft-versus-Host Disease in Patients Undergoing Hematopoietic Cell Transplantation with Minimal-Intensity Cyclophosphamide and Fludarabine, PMID: 31742732

The use of basiliximab in solid organ transplantation, PMID: 12437498

Comparison of Alemtuzumab Versus Basiliximab Induction Therapy in Elderly Kidney Transplant Recipients: A Single-Center Experience, PMID: 31315501

The role of basiliximab induction therapy in organ transplantation, PMID: 17150025

Basiliximab treatment of severe GVHD induced by donor lymphocyte infusion with interferon-a, PMID: 30589491

Early Steroid Withdrawal Protocol With Basiliximab and Rituximab in ABO-Incompatible Kidney Transplant Recipients, PMID: 32444132

Prognostic factors and long-term follow-up of basiliximab for steroid-refractory acute graft-versus-host disease: Updated experience from a large-scale study, PMID: 32311156

Clinical-economic impact of the change of protocol for use of basiliximab in liver transplant, PMID: 30624168

Opportunistic Infections After Induction With Alemtuzumab or Basiliximab: A 3-Year Kidney Transplantation Experience, PMID: 32921434

Basiliximab impairs regulatory T cell (TREG) function and could affect the short-term graft acceptance in children with heart transplantation, PMID: 33436905

Immunosuppression and Reproductive Health After Kidney Transplantation, PMID: 31397802

Thymoglobuline plus basiliximab a mixed cocktail to start?, PMID: 28676335

Anti-interleukin-2 receptor antibodies: basiliximab and daclizumab, PMID: 11522853

Comparison of basiliximab vs antithymocyte globulin for induction in pediatric heart transplant recipients: An analysis of the International Society for Heart and Lung Transplantation database, PMID: 29878688

Basiliximab: efficacy and safety evaluation in kidney transplantation, PMID: 24266670

Basiliximab for posterior reversible encephalopathy syndrome after lung transplantation, PMID: 28498905

Basiliximab induction in patients receiving tacrolimus-based immunosuppressive regimens, PMID: 23054318

Economic analysis of basiliximab in renal transplantation, PMID: 11435967

Basiliximab does not increase efficacy of corticosteroids in patients with steroid-refractory ulcerative colitis, PMID: 22549092

Low-dose basiliximab induction therapy in heart transplantation, PMID: 28990220

Thymoglobulin Versus Basiliximab Induction Therapy in Low-Risk Kidney Transplant Recipients: A Single-Center Experience, PMID: 29880348

Induction Therapy With ATG Compared With Anti-IL2 Basiliximab in Low-Immunologic Risk Kidney Transplant Recipients, PMID: 31732198

Basiliximab or antithymocyte globulin for induction therapy in kidney transplantation: a meta-analysis, PMID: 20620496

[Basiliximab following penetrating risk-keratoplasty--a prospective randomized pilot study], PMID: 18236372

Early reduction of regulatory T cells is associated with acute rejection in liver transplantation under tacrolimus-based immunosuppression with basiliximab induction, PMID: 31965710

Assessment of infectious complications in elderly kidney transplant recipients receiving induction with anti-thymocyte globulin vs basiliximab, PMID: 32031729

Use of basiliximab in pediatric liver transplantation for Langerhans cell histiocytosis, PMID: 12756053

A prospective economic evaluation of basiliximab (Simulect) therapy following renal transplantation, PMID: 11048993

[Off-label use of biologic agents in the treatment of dermatosis, part 2: etanercept, efalizumab, alefacept, rituximab, daclizumab, basiliximab, omalizumab, and cetuximab], PMID: 18206084

Basiliximab (Simulect) in renal transplantation with high risk for delayed graft function, PMID: 15866629

Basiliximab in pediatric liver transplantation: a pharmacokinetic-derived dosing algorithm, PMID: 12100507

Single-Dose Basiliximab Induction in Low-Risk Renal Transplant Recipients, PMID: 27265620

Basiliximab and heart transplantation in Hispanics: the experience in Puerto Rico, PMID: 19610574

Increased risk of rejection after basiliximab induction in sensitized kidney transplant recipients without pre-existing donor-specific antibodies - a retrospective study, PMID: 30903722

Basiliximab-chimeric anti-IL2-R monoclonal antibody in pediatric liver transplantation: comparative study, PMID: 15194332

Basiliximab induction and delayed calcineurin inhibitor initiation in liver transplant recipients with renal insufficiency, PMID: 21617588

Analysis of rabbit anti-thymocyte globulin vs basiliximab induction in pediatric liver transplant recipients, PMID: 31512802

Basiliximab in lung transplantation: preliminary experience, PMID: 15866665

Datasheet

Document Download

Research Grade Basiliximab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

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For research use only. Not for human or drug use.

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Research Grade Basiliximab [DHB95802]
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