Catalog No.
YHG33301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Tyr672-Tyr891
Predicted molecular weight
24.49 kDa
Nature
Recombinant
Concentration
0.3 mg/ml by bradford before be lyophilizion
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q12906
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in TBS pH 8.0, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
It suggests that the concentration of the protein be redissolved at 0.3mg/ml with sterile water.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
ILF3, MPHOSPH4, DRBP76, TCP80, DRBF, Translational control protein 80, M-phase phosphoprotein 4, Nuclear factor associated with dsRNA, NF90, NFAR, MPP4, NF-AT-90, Double-stranded RNA-binding protein 76, Interleukin enhancer-binding factor 3, Nuclear factor of activated T-cells 90 kDa
ILF3 mediates lipid metabolism to promote pancreatic cancer development by regulating CPT1A-activated PPARa signaling pathway., PMID:40419169
Targeting MYOF suppresses pancreatic ductal adenocarcinoma progression by inhibiting ILF3-LCN2 signaling through disrupting OTUB1-mediated deubiquitination of ILF3., PMID:40381229
Zinc finger protein 184 prevents α-synuclein preformed fibril-mediated neurodegeneration through the interleukin enhancer binding factor 3-microRNA-7 pathway., PMID:40333790
Exome Sequencing to Identify Novel Susceptibility Genes for Nonsyndromic Split-Hand/Ft Malformation: A Report From the National Birth Defects Prevention Study., PMID:40304391
The impact of an RNA-binding protein group on regulating the RSPO-LGR4/5-ZNRF3/RNF43 module and the immune microenvironment in hepatocellular carcinoma., PMID:40264052
Integrative structural analysis of NF45-NF90 heterodimers reveals architectural rearrangements and oligomerization on binding dsRNA., PMID:40156862
Simvastatin inhibits PD-L1 via ILF3 to induce ferroptosis in gastric cancer cells., PMID:40140647
Identification of antiviral RNAi regulators, ILF3/DHX9, recruit at ZIKV stem loop B to protect against ZIKV induced microcephaly., PMID:40011444
8q24 derived ZNF252P promotes tumorigenesis by driving phase separation to activate c-Myc mediated feedback loop., PMID:40011431
CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR-15b-5p and miR-7-1-3p processing in nasopharyngeal carcinoma., PMID:39964093
RNA binding protein ILF3 increases CEP55 mRNA stability to enhance malignant potential of breast cancer cells and suppress ferroptosis., PMID:39871389
The highly conserved PIWI-interacting RNA CRAPIR antagonizes PA2G4-mediated NF110-NF45 disassembly to promote heart regeneration in mice., PMID:39814981
ILF2: a multifaceted regulator in malignant tumors and its prospects as a biomarker and therapeutic target., PMID:39735599
Circular RNA circPHLPP2 promotes tumor growth and anti-PD-1 resistance through binding ILF3 to regulate IL36γ transcription in colorectal cancer., PMID:39695693
Characterising a Novel Therapeutic Target for Psoriasis, TYK2, Using Functional Genomics., PMID:39684939
ILF2 protein is a promising serum biomarker for early detection of gastric cancer., PMID:39587551
Enhancing diabetic foot ulcer healing: Impact of the regulation of the FUS and ILF2 RNA‑binding proteins through negative pressure wound therapy., PMID:39301661
Macrophage ILF3 promotes abdominal aortic aneurysm by inducing inflammatory imbalance in male mice., PMID:39179537
LncRNA ILF3-AS1 mediates oxidative stress and inflammation through miR-504-3p/HMGB1 axis in a cellular model of temporal lobe epilepsy., PMID:39135276
Single-cell sequencing combined with spatial transcriptomics reveals that the IRF7 gene in M1 macrophages inhibits the occurrence of pancreatic cancer by regulating lipid metabolism-related mechanisms., PMID:39118300
Single-cell RNA sequencing elucidated the landscape of breast cancer brain metastases and identified ILF2 as a potential therapeutic target., PMID:38943472
Lefamulin Overcomes Acquired Drug Resistance via Regulating Mitochondrial Homeostasis by Targeting ILF3 in Hepatocellular Carcinoma., PMID:38874478
Smooth muscle NF90 deficiency ameliorates diabetic atherosclerotic calcification in male mice via FBXW7-AGER1-AGEs axis., PMID:38862515
Hypoxia-responsive lncRNA MIR155HG promotes PD-L1 expression in hepatocellular carcinoma cells by enhancing HIF-1α mRNA stability., PMID:38850791
Integrating trans-omics, cellular experiments and clinical validation to identify ILF2 as a diagnostic serum biomarker and therapeutic target in gastric cancer., PMID:38622522
Deficiency of smooth muscle cell ILF3 alleviates intimal hyperplasia via HMGB1 mRNA degradation-mediated regulation of the STAT3/DUSP16 axis., PMID:38583797
Study of prognostic splicing factors in cancer using machine learning approaches., PMID:38538560
Identification of G-quadruplex-interacting proteins in living cells using an artificial G4-targeting biotin ligase., PMID:38452210
Role of ATF3 triggering M2 macrophage polarization to protect against the inflammatory injury of sepsis through ILF3/NEAT1 axis., PMID:38395749
LINC00571 drives tricarboxylic acid cycle metabolism in triple-negative breast cancer through HNRNPK/ILF2/IDH2 axis., PMID:38238853
SOX2-OT Binds with ILF3 to Promote Head and Neck Cancer Progression by Modulating Crosstalk between STAT3 and TGF-β Signaling., PMID:38136312
Pioneering 4,11-Dioxo-4,11-dihydro-1H-anthra[2,3-d]imidazol-3-ium Compounds as Promising Survivin Inhibitors by Targeting ILF3/NF110 for Cancer Therapy., PMID:38079530
ILF3 safeguards telomeres from aberrant homologous recombination as a telomeric R-loop reader., PMID:37991243
Methyl donor diet attenuates intimal hyperplasia after vascular injury in rats., PMID:37844765
LncRNA FTO-IT1 promotes glycolysis and progression of hepatocellular carcinoma through modulating FTO-mediated N6-methyladenosine modification on GLUT1 and PKM2., PMID:37840133
Genome-wide identification and functional analysis of dysregulated alternative splicing profiles in sepsis., PMID:37749550
LncRNA PTTG3P promotes tumorigenesis and metastasis of NSCLC by binding with ILF3 to maintain mRNA stability and form a positive feedback loop with E2F1., PMID:37705754
Prognostic and immunological role of cancer-associated fibroblasts-derived exosomal protein in esophageal squamous cell carcinoma., PMID:37634448
The programmed death ligand 1 interactome demonstrates bidirectional signaling coordinating immune suppression and cancer progression in head and neck squamous cell carcinoma., PMID:37389416
PSMD3-ILF3 signaling cascade drives lung cancer cell proliferation and migration., PMID:37337223
Negative regulation of HBG1/2 expression through S6K by long noncoding RNA NR_120526., PMID:37305725
A spliceosome-associated gene signature aids in predicting prognosis and tumor microenvironment of hepatocellular carcinoma., PMID:37301543
LncRNA H19 Regulates Breast Cancer DNA Damage Response and Sensitivity to PARP Inhibitors via Binding to ILF2., PMID:37298108
SARS-CoV-2 airway infection results in the development of somatosensory abnormalities in a hamster model., PMID:37159520
A network of DZF proteins controls alternative splicing regulation and fidelity., PMID:37144502
Astragaloside IV promotes keratinocyte proliferation and migration through upregulating lncRNA H19 recruited ILF3 to enhance the stability of CDK4 mRNA., PMID:37132584
Establishment and validation of exhausted CD8+ T cell feature as a prognostic model of HCC., PMID:37077914
NUSAP1 Binds ILF2 to Modulate R-Loop Accumulation and DNA Damage in Prostate Cancer., PMID:37047232
Genome-wide CRISPR screens identify ILF3 as a mediator of mTORC1-dependent amino acid sensing., PMID:37037994
Integrative network-based analysis on multiple Gene Expression Omnibus datasets identifies novel immune molecular markers implicated in non-alcoholic steatohepatitis., PMID:37008925
For research use only. Not for human or drug use.
