Catalog No.
EHF92901
Expression system
Mammalian Cells
Species
Homo sapiens (Human)
Protein length
Lys22-Lys246
Predicted molecular weight
53.83 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q02297
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Glial growth factor, Neu differentiation factor, SMDF, Breast cancer cell differentiation factor p45, Pro-neuregulin-1, membrane-bound isoform, Acetylcholine receptor-inducing activity, ARIA, GGF, HRGA, Pro-NRG1, HGL, HRG, NDF, NRG1, Sensory and motor neuron-derived factor, Heregulin, SARS-like Coronaviruses
Di (2-ethylhexyl) Phthalate decrease pregnancy rate via disrupting the microbe-gut-hypothalamic-pituitary-ovarian axis in mice., PMID:40514374
Transcriptome analysis of MRNA after different induction time of induced schwann-like cells from adipose-derived stem cells., PMID:40505047
Modeling acquired TKI resistance and effective combination therapeutic strategies in murine RET+ lung adenocarcinoma., PMID:40502048
Transcriptional landscape of pleural mesothelioma patients in relation to NF2 gene mutational status., PMID:40484892
Role of GDF-15 and NRG-1 as predictive markers of coronary artery disease., PMID:40459638
The lncRNA 74.1/miR-324-3p/NRG1 axis as a differential diagnostic and prognostic biomarker in neuromyelitis optica and multiple sclerosis., PMID:40436286
Proliferative arrest induces neuronal differentiation and innate immune responses in normal and Creutzfeldt-Jakob Disease agent (CJ) infected rat septal neurons., PMID:40434970
Genomic-Thermodynamic Phase Synchronization: Maxwell's Demon-like Regulation of Cell Fate Transition., PMID:40430050
Discovery of an APP-selective BACE1 inhibitor for Alzheimer's disease., PMID:40399225
Bispecific Antibodies in Non-Small Cell Lung Cancer: From Targeted Innovation to Real-World Integration., PMID:40397846
LncRNA PVT1 activated by TGF-β1/Smad3 facilitates proliferation and metastasis of hepatocellular carcinoma via upregulating Smad6 and NRG1., PMID:40312711
Prenatal exposure to Bisphenol A sex-specifically disrupts prepulse inhibition and decreases parvalbumin-positive neurons in the prefrontal cortex of adult rats., PMID:40311724
Diversification of dentate gyrus granule cell subtypes is regulated by Nrg1 nuclear back-signaling., PMID:40280713
Neuregulin-1 (NRG1) Binds to the Allosteric Binding Site (Site 2) and Suppresses Allosteric Integrin Activation by Inflammatory Cytokines: A Potential Mechanism of Anti-Inflammatory and Anti-Fibrosis Action of NRG1., PMID:40277942
Neuregulin-1 prevents death from a normally lethal respiratory viral infection., PMID:40267147
A Study of Sudden Cardiac Death in Schizophrenia., PMID:40263070
L-Arginine Activates the Neuregulin-1/ErbB Receptor Signaling Pathway and Increases Utrophin mRNA Levels in C2C12 Cells., PMID:40224962
eNRGy: Making progress toward a future for NRG1 fusion-positive cancer., PMID:40220746
Afatinib in patients with solid tumors with neuregulin 1 (NRG1) fusions: a case series from the Targeted Agent and Profiling Utilization Registry (TAPUR) Study., PMID:40215596
Dynamic regulation of Rgs16 and its correlation with Neuregulin1 expression in acute and chronic nerve injury., PMID:40213396
The Inflammatory Axis of LncRNA Ftx/miR-382-5p/NRG1 in the Differential Diagnosis and Prognosis of Multiple Sclerosis and Neuromyelitis Optica., PMID:40192890
GTS-21 alleviates sepsis-induced atrial fibrillation susceptibility by modulating macrophage polarization and Neuregulin-1 secretion., PMID:40186903
A protective growth factor delivery strategy based on polyphenol-protein self-assembly to promote inflammatory bone regeneration., PMID:40120176
Effect of Paliperidone Combined with Sertraline in the Treatment of Schizophrenia and its Influence on Serum Neurofunctional Related Factors., PMID:40110383
Protective Effect of Jiawei Shuxin Tang on Myocardial Ischemia-Reperfusion in Rats with Qi Deficiency and Blood Stasis and Its Correlation with NRG-1., PMID:40089277
Emerging importance of HER3 in tumorigenesis and cancer therapy., PMID:40087402
Mucosal Macrophages Govern Intestinal Regeneration in Response to Injury., PMID:40086603
Corrigendum to "Molecular structure of NRG-1 protein and its impact on adult hypertension and heart failure: A new clinical Indicator diagnosis based on advanced machine learning" [Int. J. Biol. Macromol. volume 304, Part 2 (April 2025) No page numbers (article 140955)]., PMID:40086173
Liver-derived Neuregulin1α stimulates compensatory pancreatic β cell hyperplasia in insulin resistance., PMID:40082404
Suppression of FOXO1 activity by SIRT1-mediated deacetylation weakening the intratumoral androgen autocrine function in glioblastoma., PMID:40075208
Protective role of Tongxinluo in mitigating myocardial fibrosis in mice with acute myocardial infarction via neuregulin-1 upregulation and Inhibition of endothelium-interstitial transition., PMID:40063284
Persistent behavioural consequences of chronic adolescent cannabidiol (CBD) in a mouse model with increased susceptibility to Δ9-tetrahydrocannabinol and schizophrenia., PMID:40056966
Modular mechanisms of immune priming and growth inhibition mediated by plant effector-triggered immunity., PMID:40056417
Heart Rate Reduction Is Associated With Reverse Left Ventricular Remodeling and Mechanism-Specific Molecular Phenotypes in Dilated Cardiomyopathy., PMID:40052260
Inhibition of ErbB2 mitigates secondary denervation after traumatic muscle injury., PMID:40033740
Zenocutuzumab: First Approval., PMID:39994106
New insights into CNL-mediated immunity through recognition of Ralstonia solanacearum RipP1 by NbZAR1., PMID:39968695
Elevated neuregulin‑1 expression modulates tumor malignancy and autophagy in esophageal squamous cell carcinoma., PMID:39950316
Molecular structure of NRG-1 protein and its impact on adult hypertension and heart failure: A new clinical Indicator diagnosis based on advanced machine learning., PMID:39947530
Influence of Simulated Altitude Exposure (2500 m) on Patients with Fontan Palliation Based on Circulating Hypoxia-Associated Factors., PMID:39940657
Balanced plant helper NLR activation by a modified host protein complex., PMID:39939760
Activation and inhibition mechanisms of a plant helper NLR., PMID:39939758
The Brain-Penetrant Pan-ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain Metastases., PMID:39932819
Molecular Tissue Profiling in a Clinically Selected Pancreatic Cancer Cohort., PMID:39923761
The role of the neuregulin 1-ErbB4 signaling pathway in neurological disorders., PMID:39923224
Dickkopf 1 and Neuregulin 1 as cutaneous biomarkers for dermal pigmentation activity in acquired dermal macular hyperpigmentation (ADMH): a case control study., PMID:39921734
Efficacy of Zenocutuzumab in NRG1 Fusion-Positive Cancer., PMID:39908431
Exercise Training After Myocardial Infarction Enhances Endothelial Progenitor Cells Function via NRG-1 Signaling., PMID:39893285
NRG1 Fusions: The New Kid on the Block., PMID:39888568
Neuregulin1 ameliorates metabolic dysfunction-associated fatty liver disease via the ERK/SIRT1 signaling pathways., PMID:39885382
For research use only. Not for human or drug use.
