Catalog No.
YHD57801
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Phe91-Phe352
Predicted molecular weight
31.77 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P23443
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
S6K-beta-1, 70 kDa ribosomal protein S6 kinase 1, p70 S6KA, p70-S6K 1, S6K1, Serine/threonine-protein kinase 14A, p70 ribosomal S6 kinase alpha, p70 S6 kinase alpha, STK14A, RPS6KB1, Ribosomal protein S6 kinase I, p70 S6K-alpha, P70S6K1, Ribosomal protein S6 kinase beta-1
Multiple ways to promote adult grass carp (Ctenopharyngodon idella) muscle hypertrophy: Application of dietary myo-inositol., PMID:40487104
IL-13 May Could Enhance the Proliferation and Affect the Differentiation of Nasal Epithelium Basal Cells Through the mTOR/p70S6K1 Pathway in Chronic Rhinosinusitis With Nasal Polyps., PMID:40438321
White Adipocyte Stem Cell Expansion Through Infant Formula Feeding: New Insights into Epigenetic Programming Explaining the Early Protein Hypothesis of Obesity., PMID:40429638
Effect of Dietary Protein and Lipid Level on Growth, Antioxidant, and Gene Expression of Juvenile Parabramis pekinensis., PMID:40406057
S6K1 overexpression enhances autophagy in breast cancer cells by inducing the translation of CLU., PMID:40405358
Supplementation of low-protein diets with plant protein and probiotics enhances muscle health by regulating gut microbiota and metabolomic profiles in SAMP8 mice., PMID:40391466
High-protein diets alleviate tumour growth and drug resistance by promoting AKT aggregation and turnover., PMID:40379466
The Nucleolus: A Central Hub for Ribosome Biogenesis and Cellular Regulatory Signals., PMID:40362410
TORC1 autonomously controls its spatial partitioning via the Rag GTPase tether Tco89., PMID:40359108
Quantitative Proteomic Study Reveals Amygdalin Alleviates Liver Fibrosis Through Inhibiting mTOR/PDCD4/JNK Pathway in Hepatic Stellate Cells., PMID:40356680
The Effect of Valine on the Synthesis of α-Casein in MAC-T Cells and the Expression and Phosphorylation of Genes Related to the mTOR Signaling Pathway., PMID:40243924
Platinum(II) and ruthenium(II) coordination complexes equipped with an anchoring site for binding the protein kinase enzyme pockets: synthesis, molecular docking and biological assays., PMID:40243115
Nutritional modulation of the mTORC1 pathway in muscle: differential effect according to muscle and sex., PMID:40184212
Effect of glucose supplementation on protein biosynthesis in chickens reared under thermoneutral or heat stress environment., PMID:40064307
TSC2 loss in neural progenitor cells suppresses mRNA translation of neurodevelopmental genes., PMID:40037376
Interaction of dietary replacements of fishmeal by protein blend and feeding frequency on growth performance and protein utilization of gibel carp (Carassius gibelio var. CAS V)., PMID:39995523
Tacrolimus induces insulin receptor substrate 1 hyperphosphorylation and inhibits mTORc1/S6K1 cascade in HL7702 cells., PMID:39959267
The splicing factor SRRM2 modulates two S6K kinases to promote colorectal cancer growth., PMID:39956864
Selective abrogation of S6K2 identifies lipid homeostasis as a survival vulnerability in MAPK inhibitor-resistant NRAS-mutant melanoma., PMID:39908352
Bemcentinib enhances sensitivity to estrogen receptor inhibitors in breast cancer cells., PMID:39900236
Odd-Chain Fatty Acid-Enriched Fats Improve Growth and Intestinal Morphology and Function in Milk Replacer-Fed Piglets., PMID:39889853
Inhibition of p70 Ribosomal S6K1 Protects the Myocardium against Ischemia/Reperfusion-Induced Necrosis through Downregulation of RIP3., PMID:39862085
Slowly digestible starch impairs growth performance of broiler chickens offered low-protein diet supplemental higher amino acid densities by inhibiting the utilization of intestinal amino acid., PMID:39844287
Co-expression of the RPS6KB1 and PDPK1 genes for production of activated p70S6K1 using bac-to-bac baculovirus expression system., PMID:39821712
Vaccinia growth factor-dependent modulation of the mTORC1-CAD axis upon nutrient restriction., PMID:39817770
S6K1 is a Targetable Vulnerability in Tumors Exhibiting Plasticity and Therapy Resistance., PMID:39781466
E3 ligase FBXW7 suppresses brown fat expansion and browning of white fat., PMID:39747664
Phenylalanine Regulates Milk Protein Synthesis via LAT1-mTOR Signaling Pathways in Bovine Mammary Epithelial Cells., PMID:39684845
Isothiocyanates induce autophagy and inhibit protein synthesis in primary cells via modulation of AMPK-mTORC1-S6K1 signaling pathway, and protect against mutant huntingtin aggregation., PMID:39680190
Tryptophan regulates food intake in growing pigs by modulating hypothalamic AMPK-mTOR signalling pathway., PMID:39670658
ORP5 promotes cardiac hypertrophy by regulating the activation of mTORC1 on lysosome., PMID:39667666
p21Waf1/Cip1 Is a Novel Downstream Target of 40S Ribosomal S6 Kinase 2., PMID:39594738
JC virus small tumor antigen promotes S phase entry and cell cycle progression., PMID:39586476
IBS008738, a TAZ activator, facilitates muscle repair and inhibits muscle injury in a mouse model of sport-induced injury., PMID:39575322
Anabolic Sensitivity in Healthy, Lean, Older Men Is Associated With Higher Expression of Amino Acid Sensors and mTORC1 Activators Compared to Young., PMID:39558870
Dietary Threonine Promoted the Growth and Ovarian Development of the Red Swamp Crayfish (Procambarus clarkii)., PMID:39555547
Experimentally-driven mathematical model to understand the effects of matrix deprivation in breast cancer metastasis., PMID:39532909
The Bi-steric Inhibitor RMC-5552 Reduces mTORC1 Signaling and Growth in Lymphangioleiomyomatosis., PMID:39531634
RNF19A inhibits bladder cancer progression by regulating ILK ubiquitination and inactivating the AKT/mTOR signalling pathway., PMID:39508245
Research note: Effect of a biotechnologically produced Pleurotus sapidus mycelium on expression of genes involved in protein synthesis and degradation in breast muscle of broilers., PMID:39504827
FBXO22 inhibits colitis and colorectal carcinogenesis by regulating the degradation of the S2448-phosphorylated form of mTOR., PMID:39485803
Short-chain fatty acids enhance muscle mass and function through the activation of mTOR signalling pathways in sarcopenic mice., PMID:39482890
Elevated BCAA catabolism reverses the effect of branched-chain ketoacids on glucose transport in mTORC1-dependent manner in L6 myotubes., PMID:39464407
S6K1 Controls DNA Damage Signaling Modulated by the MRN Complex to Induce Radioresistance in Lung Cancer., PMID:39408794
Antidiabetic and Antihyperlipidemic Activities and Molecular Mechanisms of Phyllanthus emblica L. Extract in Mice on a High-Fat Diet., PMID:39329975
Lactate-upregulated ARG2 expression induces cellular senescence in fibroblast-like synoviocytes of osteoarthritis via activating the mTOR/S6K1 signaling pathway., PMID:39236462
Targeting POLRMT by IMT1 inhibits colorectal cancer cell growth., PMID:39227564
Ribosomal S6 kinase 1 regulates inflammaging via the senescence secretome., PMID:39210150
Investigating the Regulation of Ribosomal Protein S6 Kinase 1 by CoAlation., PMID:39201434
Selenomethionine Promotes Milk Protein and Fat Synthesis and Proliferation of Mammary Epithelial Cells through the GPR37-mTOR-S6K1 Signaling., PMID:39177123
For research use only. Not for human or drug use.
