Catalog No.
YHD15601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Trp277
Predicted molecular weight
32.68 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P16152
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
CBR1, CRN, Prostaglandin 9-ketoreductase, Carbonyl reductase [NADPH] 1, Short chain dehydrogenase/reductase family 21C member 1, PG-9-KR, Prostaglandin-E(2) 9-reductase, 15-hydroxyprostaglandin dehydrogenase [NADP(+)], NADPH-dependent carbonyl reductase 1, CBR, 20-beta-hydroxysteroid dehydrogenase, SDR21C1
The Influence of CYP2B6, GSTP1, and SLCO1B1 Star Allele-Predicted Phenotypes and CBR1 Genetic Variants on Effectiveness Outcomes in Patients With Hepatocellular Carcinoma Receiving Doxorubicin via Transarterial Chemoembolization., PMID:40405401
Targeting the Gut-Brain Axis with Plant-Derived Essential Oils: Phytocannabinoids and Beyond., PMID:40362887
Drugs Metabolism-Related Genes Variants Impact on Anthracycline-Based Chemotherapy Induced Subclinical Cardiotoxicity in Breast Cancer Patients., PMID:40362292
SNP's use as a potential chemotoxicity stratification tool in breast cancer: from bench to clinic., PMID:40261508
Influence of Polymorphisms in Pharmacokinetics-Related Genes on the Areas Under the Plasma Concentration-Time Curves of Doxorubicin and Doxorubicinol in Patients with Diffuse Large B-Cell Lymphoma Receiving CHOP Therapy., PMID:40186087
Human skeletal muscle possesses both reversible proteomic signatures and a retained proteomic memory after repeated resistance training., PMID:40183698
Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson's disease., PMID:40122840
Lactylation modulation identifies key biomarkers and therapeutic targets in KMT2A-rearranged AML., PMID:39789150
Divergent roles of m6A in orchestrating brown and white adipocyte transcriptomes and systemic metabolism., PMID:39788955
Multi-omics analysis combined with network pharmacology revealed the mechanisms of rutaecarpine in chronic atrophic gastritis., PMID:39581285
Epigenetic effects of exercise on improving the adverse placental environment associated with maternal overweight and obesity., PMID:39579621
Cleistopholis patens root bark extract exerts cardioprotective effect against doxorubicin-induced myocardial toxicity in rats., PMID:39551811
The Expression of Cannabinoid and Cannabinoid-Related Receptors on the Gustatory Cells of the Piglet Tongue., PMID:39407543
Integrated ubiquitomics characterization of hepatocellular carcinomas., PMID:39348425
Comparing alpha-synuclein-interactomes between multiple systems atrophy and Parkinson's disease reveals unique and shared pathological features., PMID:39345456
Sanger Sequencing Reveals Novel Variants in GLO-1, ACE, and CBR1 Genes in Patients of Early and Severe Diabetic Nephropathy., PMID:39336582
The endocannabinoid system in appetite regulation and treatment of obesity., PMID:39292202
m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1., PMID:39255799
Adipocyte maturation impacts daunorubicin disposition and metabolism., PMID:39254480
Alcohol activates cannabinoid receptor 1 and 2 in a model of pathogen induced pulmonary inflammation., PMID:39251147
Prostaglandin-related genes are differentially expressed in equine endometrium with different biopsy grade, degrees of inflammation, and fibrosis., PMID:39089078
The cardioprotective properties of Persicaria maculosa and Citrus sinensis extracts against doxorubicin-induced cardiotoxicity in mice., PMID:38952773
Involvement of porcine and human carbonyl reductases in the metabolism of epiandrosterone, 11-oxygenated steroids, neurosteroids, and corticosteroids., PMID:38945307
Overexpression of carbonyl reductase 1 in ovarian cancer cells suppresses proliferation and activates the eIF2 signaling pathway., PMID:38881711
Placental Cannabinoid Receptor Expression in Preterm Birth., PMID:38745869
Proteomic analysis reveals potential therapeutic targets for childhood asthma through Mendelian randomization., PMID:38730525
Guideline directed medical therapy induced nephrotoxicity in HFrEF patients; an insight to its mechanism., PMID:38466079
CETSA-MS-based target profiling of anti-aging natural compound quercetin., PMID:38342014
In vitro evaluation of the reductive carbonyl idarubicin metabolism to evaluate inhibitors of the formation of cardiotoxic idarubicinol via carbonyl and aldo-keto reductases., PMID:38175295
(m) RVD-hemopressin (α) Ameliorated Oxidative Stress, Apoptosis and Damage to the BDNF/TrkB/Akt Pathway Induced by Scopolamine in HT22 Cells., PMID:37971633
Impact of Chronic Moderate Exercise on Immune Cells and Cytokine Levels in Rats: Focus on the Endocannabinergic Pathway., PMID:37962860
[Altered expression of 15-hydroxyprostaglandin dehydrogenase in chronic rhinosinusitis with nasal polyps]., PMID:37905483
Quantitative Analysis of mRNA and Protein Expression Levels of Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoforms in the Human Intestine., PMID:37722844
Gbp3 is associated with the progression of lupus nephritis by regulating cell proliferation, inflammation and pyroptosis., PMID:37621179
Osmotic stress-induced localisation switch of CBR1 from mitochondria to the endoplasmic reticulum triggers ATP production via β-oxidation to respond to osmotic shock., PMID:37469026
Identification and characterization of protein interactions with the major Niemann-Pick type C disease protein in yeast reveals pathways of therapeutic potential., PMID:37440478
The expression analyses of GSK3B, VEGF, ANG1, and ANG2 in human brain microvascular endothelial cells treated with the synthetic cannabinoid XLR-11., PMID:37355149
Proteomic analysis discovers potential biomarkers of early traumatic axonal injury in the brainstem., PMID:37338605
Phytocannabinoids as Potential Multitargeting Neuroprotectants in Alzheimer's Disease., PMID:37132109
Comprehensive analysis of arachidonic acid metabolism-related genes in diagnosis and synovial immune in osteoarthritis: based on bulk and single-cell RNA sequencing data., PMID:36995411
Brain-wide transcriptome-based metabolic alterations in Parkinson's disease: human inter-region and human-experimental model correlations., PMID:36928892
Adolescent exposure to low-dose Δ9-tetrahydrocannabinol depletes the ovarian reserve in female mice., PMID:36912754
Genomic and proteomic characterization of Philadelphia-like B-lineage acute lymphoblastic leukemia: A report of Indian patients., PMID:36738086
Gancao Nourishing-Yin decoction combined with methotrexate in treatment of aging CIA mice: a study based on DIA proteomic analysis., PMID:36709303
Genetic Manipulation of CB1 Cannabinoid Receptors Reveals a Role in Maintaining Proper Skeletal Muscle Morphology and Function in Mice., PMID:36555292
CBR1 decreases protein carbonyl levels via the ROS/Akt/CREB pathway to extend lifespan in the cotton bollworm, Helicoverpa armigera., PMID:36421037
Development of transgenic mice overexpressing mouse carbonyl reductase 1., PMID:36352178
Quantitative Evaluation of the Contribution of Each Aldo-Keto Reductase and Short-Chain Dehydrogenase/Reductase Isoform to Reduction Reactions of Compounds Containing a Ketone Group in the Human Liver., PMID:36310032
Dominance status is associated with a variation in cannabinoid receptor 1 expression and amphetamine reward., PMID:36270348
Five EMT-Related Gene Signatures Predict Acute Myeloid Leukemia Patient Outcome., PMID:36246561
For research use only. Not for human or drug use.
