Catalog No.
YHJ32301
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Ala67
Predicted molecular weight
9.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q92686
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
RC3, Neurogranin, Ng, NRGN
Neurogranin facilitates maintaining the immunosuppressive state of hepatocellular carcinoma by promoting TGF-β1 secretion., PMID:40316076
Elucidating SARS-CoV-2 neurotropism: a comprehensive Mendelian randomization study on cerebrospinal fluid biomarkers and their relevance to COVID-19 neurological manifestations., PMID:40296111
Molecular Biomarkers of Neurodegeneration in Amyotrophic Lateral Sclerosis., PMID:40254405
New molecular markers to differentiate carbon dioxide intoxication from asphyxia due to oxygen deficiency., PMID:40167862
Elevated serum and cerebrospinal fluid levels of the synaptophysin and neurogranin with its altered brain expression in the early phase of traumatic brain injury as a potential marker of synaptic injury., PMID:40146393
Novel plasma biomarkers of amyloid plaque pathology and cortical thickness: Evaluation of the NULISA targeted proteomic platform in an ethnically diverse cohort., PMID:39989429
Inflammatory Response of THP1 and U937 Cells: The RNAseq Approach., PMID:39768153
Selenium promotes neural development through the regulation of GPX4 and SEPP1 in an iPSC-derived neuronal model., PMID:39708777
CSF levels of brain-derived proteins correlate with brain ventricular volume in cognitively healthy 70-year-olds., PMID:39668376
Different Proteins as Biomarkers for Sac Shrinkage After Endovascular Aortic Repair of Abdominal Aortic Aneurysms., PMID:39590217
CSF neurogranin levels as a biomarker in Alzheimer's disease and frontotemporal lobar degeneration: a cross-sectional analysis., PMID:39242539
A genetic and proteomic comparison of key AD biomarkers across tissues., PMID:39077866
Benchmarking of a multi-biomarker low-volume panel for Alzheimer's Disease and related dementia research., PMID:38947090
Mitochondrial dysfunction is associated with cognitive impairment in adults with OSA without dementia., PMID:38704871
Alterations of human CSF and serum-based mitophagy biomarkers in the continuum of Alzheimer disease., PMID:38695174
Neuroinflammation driven by human immunodeficiency virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of neurogranin in vivo and in vitro., PMID:38659061
Probing molecular pathways: Illuminating the connection between COVID-19 and Alzheimer's disease through the endocannabinoid system dynamics., PMID:38619024
Evaluation of neurogranin levels in a rat model of diffuse axonal injury., PMID:38587321
Comprehensive analysis of DNA methylation gene expression profiles in GEO dataset reveals biomarkers related to malignant transformation of sinonasal inverted papilloma., PMID:38427106
Temporal-Specific Sex and Injury-Dependent Changes on Neurogranin-Associated Synaptic Signaling After Controlled Cortical Impact in Rats., PMID:38376763
CSF protein ratios with enhanced potential to reflect Alzheimer's disease pathology and neurodegeneration., PMID:38350954
Neuroinflammation driven by Human Immunodeficiency Virus-1 (HIV-1) directs the expression of long noncoding RNA RP11-677M14.2 resulting in dysregulation of Neurogranin in vivo and in vitro., PMID:38260270
Suppression of neurogranin expression by disruption of epigenetic DNA methylation in hippocampal mature granule cells after developmental exposure to neurotoxicants in rats., PMID:37926403
Molecular Characterization of Neurogranin (NRGN) Gene from Red‑Bellied Pacu (Piaractus brachypomus)., PMID:37922064
Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept., PMID:37842184
Sex, Age, and Regional Differences in CHRM1 and CHRM3 Genes Expression Levels in the Human Brain Biopsies: Potential Targets for Alzheimer's Disease-related Sleep Disturbances., PMID:36475335
Persistent Depletion of Neuroprotective Factors Accompanies Neuroinflammatory, Neurodegenerative, and Vascular Remodeling Spectra in Serum Three Months after Non-Emergent Cardiac Surgery., PMID:36289630
Early life stressful experiences escalate aggressive behavior in adulthood via changes in transthyretin expression and function., PMID:36226913
The effects of neurogranin knockdown on SERCA pump efficiency in soleus muscles of female mice fed a high fat diet., PMID:36072929
Neurogranin-like immunoreactivity in the zebrafish brain during development., PMID:36018391
Neurogranin inhibits calcineurin in murine soleus muscle: Effects of heterozygous knockdown on muscle adaptations to tenotomy and fatigue resistance., PMID:35878428
P-tau subgroups in AD relate to distinct amyloid production and synaptic integrity profiles., PMID:35841015
Low androgen level impairs erectile function of rat by regulating the Ng/CaN/AKT/eNOS pathway in penile corpus cavernosum., PMID:35678097
A new generation of AD biomarkers: 2019 to 2021., PMID:35636691
Multiple Sclerosis Biomarker Candidates Revealed by Cell-Type-Specific Interactome Analysis., PMID:35483054
A new biomarker in the differential diagnosis of epileptic seizure: Neurogranin., PMID:35152125
Serum brain injury biomarkers are gestationally and post-natally regulated in non-brain injured neonates., PMID:34923579
Generation and Release of Neurogranin, Vimentin, and MBP Proteolytic Peptides, Following Traumatic Brain Injury., PMID:34762230
Cerebrospinal fluid markers for synaptic function and Alzheimer type changes in late life depression., PMID:34645914
Comparative description of the mRNA expression profile of Na+ /K+ -ATPase isoforms in adult mouse nervous system., PMID:34415061
Brain CHID1 Expression Correlates with NRGN and CALB1 in Healthy Subjects and AD Patients., PMID:33924468
Proteomic discovery in sickle cell disease: Elevated neurogranin levels in children with sickle cell disease., PMID:33915030
Association of neurogranin gene expression with Alzheimer's disease pathology in the perirhinal cortex., PMID:33860070
Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus., PMID:33720890
Serial plasma biomarkers of brain injury in infants with neonatal encephalopathy treated with therapeutic hypothermia., PMID:33654280
Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer's disease., PMID:33279949
Decreased nesting behavior, selective increases in locomotor activity in a novel environment, and paradoxically increased open arm exploration in Neurogranin knockout mice., PMID:33270377
Molecular forms of neurogranin in cerebrospinal fluid., PMID:33249594
Neurogranin, Encoded by the Schizophrenia Risk Gene NRGN, Bidirectionally Modulates Synaptic Plasticity via Calmodulin-Dependent Regulation of the Neuronal Phosphoproteome., PMID:33032807
Extracellular vesicles in patients in the acute phase of psychosis and after clinical improvement: an explorative study., PMID:32995075
For research use only. Not for human or drug use.
