Catalog No.
YHH20601
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Asn146-Arg384
Predicted molecular weight
29.15 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15818
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
NPTX1, NP1, Neuronal pentraxin I, Neuronal pentraxin-1, NP-I
IRX2 and NPTX1 differential regulation of β-catenin underlies MEK-mediated proliferation in human neuroglial cells., PMID:40240141
Associations between cerebrospinal fluid synaptic protein biomarkers and cognitive function in bipolar disorder., PMID:40081262
Development of a prognostic model based on the ceRNA network in Triple-Negative Breast cancer., PMID:40034665
Assessing the Causal Relationship Between Plasma Proteins and Pulmonary Fibrosis: A Systematic Analysis Based on Mendelian Randomization., PMID:40001968
[Knockdown of NPTX1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells]., PMID:39856500
β-Elemene Inhibits Adrenocortical Carcinoma Cell Proliferation and Migration, and Induces Apoptosis by Up-Regulating miR-486-3p/Targeting NPTX1 Axis., PMID:39803746
Virus-Triggered Autoimmunity Was Associated With Hirschsprung's Disease Through Activation of Innate Immunity., PMID:39493374
Monitoring of activity-driven trafficking of endogenous synaptic proteins through proximity labeling., PMID:39466808
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease., PMID:39385222
A Targetable Secreted Neural Protein Drives Pancreatic Cancer Metastatic Colonization and HIF1α Nuclear Retention., PMID:39028915
Assessment of circulating proteins in thyroid cancer: Proteome-wide Mendelian randomization and colocalization analysis., PMID:38947504
Multi-analyte proteomic analysis identifies blood-based neuroinflammation, cerebrovascular and synaptic biomarkers in preclinical Alzheimer's disease., PMID:38947065
Plasma Biomarkers in Neurodegenerative Dementias: Unrevealing the Potential of Serum Oxytocin, BDNF, NPTX1, TREM2, TNF-alpha, IL-1 and Prolactin., PMID:38803182
NPTX1 Mediates the Facilitating Effects of Hypoxia-Stimulated Human Adipocytes on Adipose-Derived Stem Cell Activation and Autologous Adipose Graft Survival Rate., PMID:38789811
Cerebrospinal fluid synaptic biomarker changes in bipolar disorder - A longitudinal case-control study., PMID:38723679
Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients., PMID:38191511
Proteomic analysis by 4D label-free MS-PRM identified that Nptx1, Ptpmt1, Slc25a11, and Cpt1c are involved in diabetes-associated cognitive dysfunction., PMID:38099467
Function and regulation of miR-186-5p, miR-125b-5p and miR-1260a in chordoma., PMID:38012562
From Fruit Waste to Medical Insight: The Comprehensive Role of Watermelon Rind Extract on Renal Adenocarcinoma Cellular and Transcriptomic Dynamics., PMID:37958599
Identification of lncRNA-miRNA-mRNA ceRNA network as biomarkers for acute kidney injury., PMID:37854219
The pentraxin family in autoimmune disease., PMID:37832905
An interventional study of baicalin on neuronal pentraxin-1, neuronal pentraxin-2, and C-reactive protein in Alzheimer's disease rat model., PMID:37719746
Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease., PMID:37515330
Exploring opportunities for drug repurposing and precision medicine in cannabis use disorder using genetics., PMID:37500481
Autosomal dominant cerebellar ataxias: new genes and progress towards treatments., PMID:37479376
miR-148a-3p regulates proliferation and apoptosis of idiopathic gingival fibroma by targeting NPTX1., PMID:37357360
A prognostic model based on regulatory T-cell-related genes in gastric cancer: Systematic construction and validation., PMID:37350375
Temporal proteomics of human cerebrospinal fluid after severe traumatic brain injury., PMID:36482407
Molecular Docking and Molecular Dynamics Studies Reveal Secretory Proteins as Novel Targets of Temozolomide in Glioblastoma Multiforme., PMID:36364024
Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia., PMID:36045450
NPTX1 inhibits pancreatic cancer cell proliferation and migration and enhances chemotherapy sensitivity by targeting RBM10., PMID:35836482
Global Proteome Profiling of the Temporal Cortex of Female Rats Exposed to Chronic Stress and the Western Diet., PMID:35565902
MRKNs: Gene, Functions, and Role in Disease and Infection., PMID:35463379
Tryptophan Metabolites Regulate Neuropentraxin 1 Expression in Endothelial Cells., PMID:35216489
NPTX1 mutations trigger endoplasmic reticulum stress and cause autosomal dominant cerebellar ataxia., PMID:34788392
Downregulation of NPTX1 induces cell cycle progression through Wnt/β-catenin signaling in breast cancer., PMID:34212686
miR-139-5p mediates the palmitate-induced inhibition of insulin secretion by targeting neuronal pentraxin 1 in INS-1 cells., PMID:34142698
Long pentraxin PTX3 is upregulated systemically and centrally after experimental neurotrauma, but its depletion leaves unaltered sensorimotor deficits or histopathology., PMID:33953334
Neuropathic pain-induced cognitive dysfunction and down-regulation of neuronal pentraxin 2 in the cortex and hippocampus., PMID:33512875
[Expression and Diagnostic Value of NPTX1 in Thymoma Patients]., PMID:33478183
C1QL3 promotes cell-cell adhesion by mediating complex formation between ADGRB3/BAI3 and neuronal pentraxins., PMID:33337553
Serum level of NPTX1 is independent of serum MKRN3 in central precocious puberty., PMID:33180049
Urban air particulate matter induces mitochondrial dysfunction in human olfactory mucosal cells., PMID:32487172
Physiological Tau Interactome in Brain and Its Link to Tauopathies., PMID:32357304
Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia., PMID:32273328
Long non coding RNA SLC26A4-AS1 exerts antiangiogenic effects in human glioma by upregulating NPTX1 via NFKB1 transcriptional factor., PMID:32255252
Hsa_circ_0070269 inhibits hepatocellular carcinoma progression through modulating miR-182/NPTX1 axis., PMID:31606623
Tumor Transcriptome Reveals High Expression of IL-8 in Non-Small Cell Lung Cancer Patients with Low Pectoralis Muscle Area and Reduced Survival., PMID:31455042
MiR-4295 facilitates cell proliferation and metastasis in head and neck squamous cell carcinoma by targeting NPTX1., PMID:31118494
As a downstream target of the AKT pathway, NPTX1 inhibits proliferation and promotes apoptosis in hepatocellular carcinoma., PMID:31113871
For research use only. Not for human or drug use.
