Catalog No.
YHH16501
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ala2-Tyr268
Predicted molecular weight
32.18 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q15691
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
EB1, Microtubule-associated protein RP/EB family member 1, MAPRE1, APC-binding protein EB1, End-binding protein 1
KHSRP promotes the malignant behavior and cisplatin resistance of bladder cancer cells through the CLASP2/MAPRE1 axis., PMID:40382315
Condensation-dependent multivalent interactions of EB1 and CENP-R regulate chromosome oscillations in mitosis., PMID:40349345
Downregulation of EB1 impedes Cx43 localization and cardiac conduction after hypothermic ischemia-reperfusion in rats., PMID:40247841
Experimental Conditions to Retrieve Intrinsic Cooperativity α Directly from Single Binding Assay Data Exemplified by the Ternary Complex Formation of FKBP12, MAPRE1 and Macrocyclic Molecular Glues., PMID:40243574
Identification and characterization of ternary complexes consisting of FKBP12, MAPRE1 and macrocyclic molecular glues., PMID:40059881
Hippocampal dendritic spines store-operated calcium entry and endoplasmic reticulum content is dynamic microtubule dependent., PMID:39779788
Proteomic snapshot of saliva samples predicts new pathways implicated in SARS-CoV-2 pathogenesis., PMID:38778280
Microtubule-associated protein MAP7 promotes tubulin posttranslational modifications and cargo transport to enable osmotic adaptation., PMID:38574732
Organization of microtubule plus-end dynamics by phase separation in mitosis., PMID:38323478
Two cases of mycosis fungoides with large cell transformation with KMT2A rearrangements., PMID:38175436
A novel missense variant in CDK5RAP2 associated with non-obstructive azoospermia., PMID:38008501
End-binding protein 1 regulates the metabolic fate of CD4+ T lymphoblasts and Jurkat T cells and the organization of the mitochondrial network., PMID:37520527
Function of TRPC1 in modulating hepatocellular carcinoma progression., PMID:36797544
Growth cone advance requires EB1 as revealed by genomic replacement with a light-sensitive variant., PMID:36715499
Kinetochore-microtubule attachment in human cells is regulated by the interaction of a conserved motif of Ska1 with EB1., PMID:36592928
Phase separation of EB1 guides microtubule plus-end dynamics., PMID:36536176
Chemical Proteomics Reveals Protein Tyrosination Extends Beyond the Alpha-Tubulins in Human Cells., PMID:36218090
miR-10a-5p inhibits chicken granulosa cells proliferation and Progesterone(P4) synthesis by targeting MAPRE1 to suppress CDK2., PMID:36084389
Genetic Control of Kinetochore-Driven Microtubule Growth in Drosophila Mitosis., PMID:35883570
Candidate genes for polycystic ovary syndrome are regulated by TGFβ in the bovine foetal ovary., PMID:35413103
Transcriptome unveiled the gene expression patterns of root architecture in drought-tolerant and sensitive wheat genotypes., PMID:35247694
MiR-526b-3p Inhibits the Resistance of Glioma Cells to Adriamycin by Targeting MAPRE1., PMID:35198024
Proteomic identification of arginine-methylated proteins in colon cancer cells and comparison of messenger RNA expression between colorectal cancer and adjacent normal tissues., PMID:35081685
Condensed, Microtubule-coating Thin Organelles for Orthogonal Translation in Mammalian Cells., PMID:35033560
Circular RNA SOX13 promotes malignant behavior and cisplatin resistance in non-small cell lung cancer through targeting microRNA-3194-3p/microtubule-associated protein RP/EB family member 1., PMID:34709968
iASPP contributes to cell cortex rigidity, mitotic cell rounding, and spindle positioning., PMID:34705028
CRMP2 as a Candidate Target to Interfere with Lung Cancer Cell Migration., PMID:34680167
Dynamic crotonylation of EB1 by TIP60 ensures accurate spindle positioning in mitosis., PMID:34608293
Gradual compaction of the central spindle decreases its dynamicity in PRC1 and EB1 gene-edited cells., PMID:34580180
Cyclical phosphorylation of LRAP35a and CLASP2 by GSK3β and CK1δ regulates EB1-dependent MT dynamics in cell migration., PMID:34525355
Molecular mechanisms underlying the role of the centriolar CEP164-TTBK2 complex in ciliopathies., PMID:34499853
α-tubulin tail modifications regulate microtubule stability through selective effector recruitment, not changes in intrinsic polymer dynamics., PMID:34022132
Introducing ADNP and SIRT1 as new partners regulating microtubules and histone methylation., PMID:33967268
EB1 Restricts Breast Cancer Cell Invadopodia Formation and Matrix Proteolysis via FAK., PMID:33668531
MAPRE2 mutations result in altered human cranial neural crest migration, underlying craniofacial malformations in CSC-KT syndrome., PMID:33654163
The Network of Interactions Between Classical Swine Fever Virus Nonstructural Protein p7 and Host Proteins., PMID:33329485
Distinct retrograde microtubule motor sets drive early and late endosome transport., PMID:33215754
circSETD3 regulates MAPRE1 through miR-615-5p and miR-1538 sponges to promote migration and invasion in nasopharyngeal carcinoma., PMID:33122825
EB1 Directly Regulates APC-Mediated Actin Nucleation., PMID:33007249
Adenomatous polyposis coli-binding protein end-binding 1 promotes hepatocellular carcinoma growth and metastasis., PMID:32956413
HIV-1 capsids mimic a microtubule regulator to coordinate early stages of infection., PMID:32896909
MAPRE1 promotes cell cycle progression of hepatocellular carcinoma cells by interacting with CDK2., PMID:32770827
Redox-dependent regulation of end-binding protein 1 activity by glutathionylation., PMID:32737853
Novel destabilizing Dynactin variant (DCTN1 p.Tyr78His) in patient with Perry syndrome., PMID:32712562
Analysis of expression of candidate genes for polycystic ovary syndrome in adult and fetal human and fetal bovine ovaries†., PMID:32678441
PTPN22 interacts with EB1 to regulate T-cell receptor signaling., PMID:32469452
Digital Spindle: A New Way to Explore Mitotic Functions by Whole Cell Data Collection and a Computational Approach., PMID:32438637
MiR-93 is related to poor prognosis in pancreatic cancer and promotes tumor progression by targeting microtubule dynamics., PMID:32366853
Tubulin tails and their modifications regulate protein diffusion on microtubules., PMID:32245812
Accelerated Lysis and Proteolytic Digestion of Biopsy-Level Fresh-Frozen and FFPE Tissue Samples Using Pressure Cycling Technology., PMID:32182071
For research use only. Not for human or drug use.
