Catalog No.
YHG82001
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser266-Gly420
Predicted molecular weight
20.04 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14533
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Keratin, hair, basic, 1, KRT81, ghHKb1, Keratin, type II cuticular Hb1, Type-II keratin Kb21, Keratin-81, Type II hair keratin Hb1, MLN 137, K81, ghHb1, Hair keratin K2.9, MLN137, Metastatic lymph node 137 gene protein, KRTHB1
The Prognostic, Predictive and Clinicopathological Implications of KRT81/HNF1A- and GATA6-Based Transcriptional Subtyping in Pancreatic Cancer., PMID:40149962
Single-cell RNA and T-cell receptor sequencing unveil mycosis fungoides heterogeneity and a possible gene signature., PMID:39169943
A nonsense variant in KRT31 is associated with autosomal dominant monilethrix., PMID:39026424
iTRAQ-based quantitative proteomics revealing the therapeutic mechanism of a medicinal and edible formula YH0618 in reducing doxorubicin-induced alopecia by targeting keratins and TGF-β/Smad3 pathway., PMID:39021977
Ovine KRT81 Variants and Their Influence on Selected Wool Traits of Commercial Value., PMID:38927617
KRT81 and HNF1A expression in pancreatic ductal adenocarcinoma: investigation of predictive and prognostic value of immunohistochemistry-based subtyping., PMID:38750616
Lgr6-expressing functional nail stem-like cells differentiated from human-induced pluripotent stem cells., PMID:38743670
Understanding the effects of per- and polyfluoroalkyl substances on early skin development: Role of ciliogenesis inhibition and altered microtubule dynamics., PMID:38163615
Ectopic Expression of a Truncated Isoform of Hair Keratin 81 in Breast Cancer Alters Biophysical Characteristics to Promote Metastatic Propensity., PMID:37949677
MAPK1 promotes the metastasis and invasion of gastric cancer as a bidirectional transcription factor., PMID:37817112
Smoking during pregnancy is associated with the placental proteome., PMID:37209868
Cashmere production, skin characteristics, and mutated genes in crimped cashmere fibre goats., PMID:35714387
Construction of a prognostic risk assessment model for lung adenocarcinoma based on Integrin β family-related genes., PMID:35403268
Autosomal recessive monilethrix: Novel variants of the DSG4 gene in three Chinese families., PMID:35146972
Prognosis and tumor biology of pancreatic cancer patients with isolated lung metastases: translational results from the German multicenter AIO-YMO-PAK-0515 study., PMID:35121522
KRT81 Knockdown Inhibits Malignant Progression of Melanoma Through Regulating Interleukin-8., PMID:34591651
In-Silico Analysis of Differentially Expressed Genes and Their Regulating microRNA Involved in Lymph Node Metastasis in Invasive Breast Carcinoma., PMID:34396887
An integrated scalp and blood biomarker approach suggests the systemic nature of alopecia areata., PMID:33721346
Screening the key genes of prognostic value in the microenvironment for head and neck squamous cell carcinoma., PMID:33530209
A Polymorphism at the microRNA Binding Site in the 3' Untranslated Region of KRT81 Is Associated with Breast Cancer., PMID:32678982
A machine learning algorithm predicts molecular subtypes in pancreatic ductal adenocarcinoma with differential response to gemcitabine-based versus FOLFIRINOX chemotherapy., PMID:31577805
CFTR Expression Analysis for Subtyping of Human Pancreatic Cancer Organoids., PMID:31191661
Recombinant Human Hair Keratin Nanoparticles Accelerate Dermal Wound Healing., PMID:31038908
Biomarkers for subtypes of pancreatic ductal adenocarcinoma., PMID:29129444
Pancreatic Ductal Adenocarcinoma Subtyping Using the Biomarkers Hepatocyte Nuclear Factor-1A and Cytokeratin-81 Correlates with Outcome and Treatment Response., PMID:29101303
Proteomic-based investigations on the mode of action of the marine anticancer compound rhizochalinin., PMID:28445005
Hair keratin KRT81 is expressed in normal and breast cancer cells and contributes to their invasiveness., PMID:28405679
CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma., PMID:26855150
KRT81 miR-SNP rs3660 is associated with risk and survival of NSCLC., PMID:26578733
Reply to the letter to the editor 'KRT81 miR-SNP rs3660 is associated with risk and survival of NSCLC' by Robles et al., PMID:26578724
A novel KRT86 mutation in a Turkish family with monilethrix, and identification of maternal mosaicism., PMID:25809918
A genetic variation in microRNA target site of KRT81 gene is associated with survival in early-stage non-small-cell lung cancer., PMID:25716425
Novel KRT83 and KRT86 mutations associated with monilethrix., PMID:25557232
A miR-SNP of the KRT81 gene is associated with the prognosis of non-Hodgkin's lymphoma., PMID:24530479
MiR-SNPs as markers of toxicity and clinical outcome in Hodgkin lymphoma patients., PMID:23705004
Frizzled6 deficiency disrupts the differentiation process of nail development., PMID:23439395
Diffuse epidermolytic palmoplantar keratoderma (Unna-Thost-)., PMID:23144341
A novel monilethrix mutation in coil 2A of KRT86 causing autosomal dominant monilethrix with incomplete penetrance., PMID:22670615
Damage of hair follicle stem cells and alteration of keratin expression in external radiation-induced acute alopecia., PMID:22692500
Impact of MiRSNPs on survival and progression in patients with multiple myeloma undergoing autologous stem cell transplantation., PMID:22539802
A dual role for KRT81: a miR-SNP associated with recurrence in non-small-cell lung cancer and a novel marker of squamous cell lung carcinoma., PMID:21799879
Annotation of sheep keratin intermediate filament genes and their patterns of expression., PMID:21554405
A case of monilethrix caused by novel compound heterozygous mutations in the desmoglein 4 (DSG4) gene., PMID:21495994
GATA3 inhibits breast cancer growth and pulmonary breast cancer metastasis., PMID:19483726
The hairless phenotype of the Hirosaki hairless rat is due to the deletion of an 80-kb genomic DNA containing five basic keratin genes., PMID:18420582
Transcriptional activation of a subset of hair keratin genes by the NF-kappaB effector p65/RelA., PMID:18021261
A missense mutation in the type II hair keratin hHb3 is associated with monilethrix., PMID:15744029
For research use only. Not for human or drug use.
