Catalog No.
YHG81401
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Ser25-Phe560
Predicted molecular weight
62.37 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q14520
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hyaluronan-binding protein 2, HABP2, Plasma hyaluronan-binding protein, Factor VII-activating protease, PHBP, Hepatocyte growth factor activator-like protein, FSAP, Factor seven-activating protease, HGFAL
Matrine alleviates Staphylococcus aureus-induced acute lung injury in mice by inhibiting MLKL and NLRP3-mediated inflammatory activity., PMID:39956265
Genome-Wide Association Study for Test-Day Milk Yield, Proteins, and Composition Traits of Crossbred Dairy Cattle in Ethiopia., PMID:39473539
Muscle growth differences in Lijiang pigs revealed by ATAC-seq multi-omics., PMID:39253524
Autoimmune hypothyroidism GWAS reveals independent autoimmune and thyroid-specific contributions and an inverse relation with cancer risk., PMID:39041034
Discovery of Pathogenic Variants Associated with Idiopathic Recurrent Pregnancy Loss Using Whole-Exome Sequencing., PMID:38791485
Proteomics-driven noninvasive screening of circulating serum protein panels for the early diagnosis of hepatocellular carcinoma., PMID:38110372
Urinary Protein-Biomarkers Reliably Indicate Very Early Kidney Damage in Children With Alport Syndrome Independently of Albuminuria and Inflammation., PMID:38106579
A New Player in the Mechanobiology of Deep Fascia: Yes-Associated Protein (YAP)., PMID:37895068
HABP2 Encapsulated by Peripheral Blood-Derived Exosomes Suppresses Astrocyte Autophagy to Exacerbate Neuroinflammatory Injury in Mice with Ischemic Stroke., PMID:37294185
Inflammation and endothelial function-related gene polymorphisms are associated with carotid atherosclerosis-A study of community population in Southwest China., PMID:37137812
A novel DNA methylation-related gene signature for the prediction of overall survival and immune characteristics of ovarian cancer patients., PMID:36978087
FSAP Protects against Histone-Mediated Increase in Endothelial Permeability In Vitro., PMID:36430180
DAR 16-II Primes Endothelial Cells for Angiogenesis Improving Bone Ingrowth in 3D-Printed BCP Scaffolds and Regeneration of Critically Sized Bone Defects., PMID:36358970
Development of a Factor VII Activating Protease (FSAP) generation assay and its application in studying FSAP in venous thrombosis., PMID:36265411
Factor VII activating protease (FSAP) inhibits the outcome of ischemic stroke in mouse models., PMID:36165219
Codonopsis pilosula polysaccharides attenuate Escherichia coli-induced acute lung injury in mice., PMID:35818994
TLR2, TLR4, and NLRP3 mediated the balance between host immune-driven resistance and tolerance in Staphylococcus aureus-infected mice., PMID:35811022
Plasma Proteomic Changes of Atherosclerosis after Exercise in ApoE Knockout Mice., PMID:35205118
FSAP aggravated endothelial dysfunction and neurological deficits in acute ischemic stroke due to large vessel occlusion., PMID:34992208
Factor VII activating protease (FSAP) is not essential in the pathophysiology of angioedema in patients with C1 inhibitor deficiency., PMID:34973499
Proteolytic activation of the epithelial sodium channel (ENaC) by factor VII activating protease (FSAP) and its relevance for sodium retention in nephrotic mice., PMID:34870751
Endometrial Expression of Cell Adhesion Genes in Recurrent Implantation Failure Patients in Ongoing IVF Cycle., PMID:34410653
Genome-wide association study of cardiac troponin I in the general population., PMID:33961016
Clinical and Genetic Features of a Large Monocentric Series of Familial Non-Medullary Thyroid Cancers., PMID:33488516
Diagnostic and prognostic value of HABP2 as a novel biomarker for endometrial cancer., PMID:33241013
Altered oxidative stress markers in relation to T cells, NK cells & killer immunoglobulin receptors that are associated with disease activity in SLE patients., PMID:32998620
DEFB4A is a potential prognostic biomarker for colorectal cancer., PMID:32863927
BROX haploinsufficiency in familial nonmedullary thyroid cancer., PMID:32385852
[Establishment and gene expression analysis of drug-resistant cell lines in hepatocellular carcinoma induced by sorafenib]., PMID:32306000
Design and Characterization of a New pVII Combinatorial Phage Display Peptide Library for Protease Substrate Mining Using Factor VII Activating Protease (FSAP) as Model., PMID:32180321
Cellular effects of factor VII activating protease (FSAP)., PMID:32087413
Inflammation and Endothelial Function Relevant Genetic Polymorphisms and Carotid Plaque in Chinese Population., PMID:31956237
Protease activated receptors (PAR)-1 and -2 mediate cellular effects of factor VII activating protease (FSAP)., PMID:31914657
Characterization of the enzymatic activity of the serine protease domain of Factor VII activating protease (FSAP)., PMID:31831842
VEGF-A-Cleavage by FSAP and Inhibition of Neo-Vascularization., PMID:31698750
Association between FSAP 1601G>A polymorphism and venous thromboembolism risk: A meta-analysis., PMID:31635523
Fluorescent activity-based probe for the selective detection of Factor VII activating protease (FSAP) in human plasma., PMID:31479940
Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner., PMID:31407948
Origin and diversification of the plasminogen activation system among chordates., PMID:30654737
A hyaluronic acid binding peptide-polymer system for treating osteoarthritis., PMID:30149233
Hyaluronan-binding protein 2 (HABP2) gene variation in women with recurrent miscarriage., PMID:30143058
Altered structure and function of fibrinogen after cleavage by Factor VII Activating Protease (FSAP)., PMID:30076961
Genome-wide analysis of genetic determinants of circulating factor VII-activating protease (FSAP) activity., PMID:30070759
Expression of the Marburg I Single Nucleotide Polymorphism (MI-SNP) and the Marburg II Single Nucleotide Polymorphism (MII-SNP) of the Factor VII-Activating Protease (FSAP) Gene and Risk of Coronary Artery Disease (CAD): A Pilot Study in a Single Population., PMID:29927903
Frequent and Rare HABP2 Variants Are Not Associated with Increased Susceptibility to Familial Nonmedullary Thyroid Carcinoma in the Spanish Population., PMID:29895015
Common genetic variation and novel loci associated with volumetric mammographic density., PMID:29665850
Interaction of factor VII activating protease (FSAP) with neutrophil extracellular traps (NETs)., PMID:29178989
Silencing of CEMIP suppresses Wnt/β-catenin/Snail signaling transduction and inhibits EMT program of colorectal cancer cells., PMID:29173982
A Positively Charged Surface Triggers Coagulation Activation Through Factor VII Activating Protease (FSAP)., PMID:29091393
Factor VII activating protease (FSAP) regulates the expression of inflammatory genes in vascular smooth muscle and endothelial cells., PMID:28881271