Catalog No.
YHG16201
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met24-Leu221
Predicted molecular weight
23.88 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q08380
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Basement membrane autoantigen p105, Galectin-3-binding protein, MAC2BP, Mac-2 BP, M2BP, Mac-2-binding protein, Tumor-associated antigen 90K, Lectin galactoside-binding soluble 3-binding protein, LGALS3BP
LGALS3BP antibody-drug conjugate enhances tumor-infiltrating lymphocytes and synergizes with immunotherapy to restrain neuroblastoma growth., PMID:40217513
LGALS3BP: A Potential Prognostic Biomarker Influencing Antitumor Immunity in Triple-negative Breast Cancer., PMID:39838686
Secreted LGALS3BP facilitates distant metastasis of breast cancer., PMID:39789641
Lung cancer exosomal Gal3BP promotes osteoclastogenesis with potential connotation in osteolytic metastasis., PMID:39516568
Exploring the role of galectin-9 and artemin as biomarkers in long COVID with chronic fatigue syndrome: links to inflammation and cognitive function., PMID:39386210
Galectin 3-binding protein (LGALS3BP) depletion attenuates hepatic fibrosis by reducing transforming growth factor-β1 (TGF-β1) availability and inhibits hepatocarcinogenesis., PMID:39073023
Aberrant expression of LGALS3BP drives an unfavorable prognosis and more aggressive in HCC via regulating PI3K/AKT signaling., PMID:39029315
Galectin-3-Binding Protein Inhibits Extracellular Heparan 6-O-Endosulfatase Sulf-2., PMID:38825040
LGALS3BP is a novel and potential biomarker in clear cell renal cell carcinoma., PMID:38393692
Integrated plasma proteomics and N-glycoproteomics reveals alterations in the N-glycosylation in Chinese hepatocellular carcinoma patients., PMID:38345243
Potential of Mac-2-binding protein glycan isomer as a new therapeutic target in pancreatic cancer., PMID:38321872
Anti-LGALS3BP antibody-drug conjugate treatment induces durable and potent antitumor response in a preclinical model of adenoid cystic carcinoma., PMID:37988837
LGALS3BP is a potential target of antibody-drug conjugates in oral squamous cell carcinoma., PMID:37649401
Polymeric immunoglobulin receptor and galectin-3-binding protein are raised in biliary atresia: Reveals a proteomic-based study., PMID:37467891
Extracellular LGALS3BP: a potential disease marker and actionable target for antibody-drug conjugate therapy in glioblastoma., PMID:37195369
Visualizing Galectin-3 Binding Protein Expression with ImmunoPET., PMID:37191353
Circular RNA circARHGEF28 inhibited the progression of prostate cancer via the miR-671-5p/LGALS3BP/NF-κB axis., PMID:37186007
90K/LGALS3BP expression is upregulated in COVID-19 but may not restrict SARS-CoV-2 infection., PMID:37162650
Urine Galectin-3 binding protein reflects nephritis activity in systemic lupus erythematosus., PMID:36508734
Platelet LGALS3BP as a Mediator of Myeloid Inflammation in Systemic Lupus Erythematosus., PMID:36245285
LGALS3BP in Microglia Promotes Retinal Angiogenesis Through PI3K/AKT Pathway During Hypoxia., PMID:35895036
Antibody-mediated blockade for galectin-3 binding protein in tumor secretome abrogates PDAC metastasis., PMID:35858411
Endometrial galectin-3 causes endometriosis by supporting eutopic endometrial cell survival and engraftment in the peritoneal cavity., PMID:35366371
Urinary galectin-3 binding protein (G3BP) as a biomarker for disease activity and renal pathology characteristics in lupus nephritis., PMID:35346341
Lectin galactoside-binding soluble 3 binding protein mediates methotrexate resistance in choriocarcinoma cell lines., PMID:35038949
Human herpesvirus infections and circulating microvesicles expressing galectin-3 binding protein in patients with systemic lupus erythematosus., PMID:34874835
Association of Serum Galectin-3-Binding Protein and Metabolic Syndrome in a Chinese Adult Population., PMID:34858323
Combined proteomic/transcriptomic signature of recurrence post-liver transplantation for hepatocellular carcinoma beyond Milan., PMID:34794390
A novel serum biomarker quintet reveals added prognostic value when combined with standard clinical parameters in prostate cancer patients by predicting biochemical recurrence and adverse pathology., PMID:34767586
Extracellular LGALS3BP regulates neural progenitor position and relates to human cortical complexity., PMID:34728600
Mac-2 binding protein glycosylation isomer is a potential biomarker to predict portal hypertension and bacterial infection in cirrhotic patients., PMID:34648567
Role of galectin 3 binding protein in cancer progression: a potential novel therapeutic target., PMID:34565385
N-glycan structures of Wisteria floribunda agglutinin-positive Mac2 binding protein in the serum of patients with liver fibrosis†., PMID:34192302
SARS-CoV-2 RNAemia and proteomic trajectories inform prognostication in COVID-19 patients admitted to intensive care., PMID:34099652
LGALS3BP/Gal-3 promotes osteogenic differentiation of human periodontal ligament stem cells., PMID:34052527
Serum galectin-3BP as a novel marker of obesity and metabolic syndrome in Chinese adolescents., PMID:33910911
Elevated plasma levels of galectin-3 binding protein are associated with post-stroke delirium - A pilot study., PMID:33901789
MZT2A promotes NSCLC viability and invasion by increasing Akt phosphorylation via the MOZART2 domain., PMID:33754417
90K predicts the prognosis of glioma patients and enhances tumor lysate-pulsed DC vaccine for immunotherapy of GBM in vitro., PMID:33686953
Microvesicles in active lupus nephritis show Toll-like receptor 9-dependent co-expression of galectin-3 binding protein and double-stranded DNA., PMID:33354779
Galectin-3-binding protein is a novel predictor of venous thromboembolism in systemic lupus erythematosus., PMID:33337998
Elevated serum levels of galectin-3 binding protein are associated with insulin resistance in non-diabetic women after menopause., PMID:33218405
Plasma exosomes from endometrial cancer patients contain LGALS3BP to promote endometrial cancer progression., PMID:33208911
Daily Monitoring of Serum Wisteria floribunda Agglutinin-Positive Mac-2 Binding Protein Is Useful for Predicting Therapeutic Effect of Tolvaptan in Cirrhotic Ascites., PMID:33208569
Surface-enhanced Raman scattering (SERS)-based immunosystem for ultrasensitive detection of the 90K biomarker., PMID:32875368
Clinical Utility of Mac-2 Binding Protein Glycosylation Isomer in Chronic Liver Diseases., PMID:32829576
Mac-2 binding protein glycosylation isomer as a novel predictive biomarker for patient survival after hepatitis C virus eradication by DAAs., PMID:32770465
Post-Treatment M2BPGi Level and the Rate of Autotaxin Reduction are Predictive of Hepatocellular Carcinoma Development after Antiviral Therapy in Patients with Chronic Hepatitis C., PMID:32630450
M2BPGi for assessing liver fibrosis in patients with hepatitis C treated with direct-acting antivirals., PMID:32550761
Comparing serum protein levels can aid in differentiating HPV-negative and -positive oropharyngeal squamous cell carcinoma patients., PMID:32542012
For research use only. Not for human or drug use.
