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Research Grade Gosuranemab (DHC82401)

Host species:Chimeric
Isotype:IgG4-kappa
Applications:Research Grade Biosimilar
Expression system:Mammalian Cells
Overview

Catalog No.

DHC82401

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Chimeric

Isotype

IgG4-kappa

Clonality

Monoclonal

Target

MAPTL, Paired helical filament-tau, MTBT1, Microtubule-associated protein tau, TAU, Neurofibrillary tangle protein, MAPT, PHF-tau

Concentration

2.46 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P10636

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BMS-986168, IPN-002, huIPN-002, CAS: 1788032-39-2

Clone ID

Gosuranemab

Data Image
  • SDS-PAGE
    SDS PAGE for Gosuranemab
  • Bioactivity
    Detects MAPT/Tau/PHF-tau in indirect ELISAs.
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Alzheimer's disease: Recent treatment strategies, PMID: 32941929

Characterization of tau binding by gosuranemab, PMID: 32991997

Tau immunotherapy is associated with glial responses in FTLD-tau, PMID: 33950293

Immunotherapy in progressive supranuclear palsy, PMID: 32657895

Safety and efficacy of anti-tau monoclonal antibody gosuranemab in progressive supranuclear palsy: a phase 2, randomized, placebo-controlled trial, PMID: 34385707

Safety of the tau-directed monoclonal antibody BIIB092 in progressive supranuclear palsy: a randomised, placebo-controlled, multiple ascending dose phase 1b trial, PMID: 31122495

Datasheet

Document Download

Research Grade Gosuranemab.pdf

 

$ 328
Product specifications
100 μg 328 1 mg 1314

Contact Information

Order: order@antibodysystem.com

Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Research Grade Gosuranemab [DHC82401]
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