Catalog No.
YHD97701
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Lys169
Predicted molecular weight
21.78 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P31948
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Hop, Transformation-sensitive protein IEF SSP 3521, Hsc70/Hsp90-organizing protein, Renal carcinoma antigen NY-REN-11, Stress-induced-phosphoprotein 1, STI1, STIP1
Unveiling the Potential Binding Targets of Celastrol in Colorectal Cancer: A Proteomic Profiling Approach Integrating Cellular Thermal Shift Assay and Pulse Proteolysis., PMID:40480957
Ubiquitin-proteasome Pathway-linked Gene Signatures as Prognostic Indicators in Prostate Cancer., PMID:40295064
New insights into Sti1/Hop's cochaperone function highlight the complexity of proteostatic regulation., PMID:40259657
Doublecortin-like kinase 1, regulated by STIP1 homology and U-box containing protein 1 or Sp1 transcription factor, affects the malignant behaviors and drug sensitivity in adriamycin-resistant breast cancer cells., PMID:40257489
The causal effects of 2,821 protein level ratios on non-small cell lung cancer: a two-sample Mendelian randomization study., PMID:40104726
Proteomic biomarkers in psoriatic arthritis., PMID:40096904
Novel tissue biomarker candidates to predict both deep venous thrombosis and healing outcome after Achilles tendon rupture., PMID:40025102
Stub1 Acetylation by CBP/p300 Attenuates Chronic Hypoxic-driven Pulmonary Hypertension by Suppressing HIF-2α., PMID:40019849
Gestational autoantibody exposure impacts early brain development in a rat model of MAR autism., PMID:39929953
Mechanism of chaperone recruitment and retention on mitochondrial precursors., PMID:39878680
Regulation of interferon alpha production by the MAGUK-family protein CASK under H5N1 infection., PMID:39850902
Stress-inducible phosphoprotein 1 (Sti1/Stip1/Hop) sequesters misfolded proteins during stress., PMID:39739753
GOLPH3-STIP1 Complex Activates STAT3 Through Exosome Secretion to Induce Colon Cancer Metastasis., PMID:39711092
Clinical and functional characterization of a novel STUB1 mutation in a Chinese spinocerebellar ataxia 48 pedigree., PMID:39707479
Hsp70-Hsp90 organising protein (HOP/STIP1) is required for KSHV lytic replication., PMID:39607759
The Keap1-Nrf2/ARE signaling pathway regulates redox balance and apoptosis in the small yellow croaker (Larimichthys polyactis) under hypoxic stress., PMID:39521089
STAT6 promotes innate immunity against BEFV and VSV by inhibiting STUB1 and NIX-mediated MAVS degradation., PMID:39471658
Kinesin-1 mediates proper ER folding of the CaV1.2 channel and maintains mouse glucose homeostasis., PMID:39322740
In silico characterization and homology modeling of Nile tilapia (Oreochromis niloticus) Hsp70cBi and Hsp70cBc proteins., PMID:39183877
SVIP reduces IGFBP-2 expression and inhibits glioblastoma progression via stabilizing PTEN., PMID:39138166
Proteostasis perturbation of N-Myc leveraging HSP70 mediated protein turnover improves treatment of neuroendocrine prostate cancer., PMID:39103353
Staphylococcus aureus infection initiates hypoxia-mediated STIP1 homology and U-box containing protein 1 upregulation to trigger osteomyelitis., PMID:39059559
Short-Term Statin Therapy Induces Hepatic Insulin Resistance Through HNF4α/PAQR9/PPM1α Axis Regulated AKT Phosphorylation., PMID:38970167
Promotion of stem cell-like phenotype of lung adenocarcinoma by FAM83A via stabilization of ErbB2., PMID:38942760
20(R)-Panaxatriol enhances METTL3-mediated m6A modification of STUB1 to inhibit autophagy and exert antitumor effects in Triple-Negative Breast Cancer cells., PMID:38823344
The ubiquitin ligase STUB1 suppresses tumorigenesis of renal cell carcinomas through regulating YTHDF1 stability., PMID:38795009
Diagnostic value of serum STIP1 in HCC and AFP-negative HCC., PMID:38780206
Grp78 destabilization of infectious prions is strain-specific and modified by multiple factors including accessory chaperones and pH., PMID:38718859
Cross-talk between BCKDK-mediated phosphorylation and STUB1-dependent ubiquitination degradation of BCAT1 promotes GBM progression., PMID:38621458
Stress-induced phosphoprotein 1: how does this co-chaperone influence the metastasis steps?, PMID:38581620
STUB1 exacerbates calcium oxalate-induced kidney injury by modulating reactive oxygen species-mediated cellular autophagy via regulating CFTR ubiquitination., PMID:38564006
STUB1 is acetylated by KAT5 and alleviates myocardial ischemia-reperfusion injury through LATS2-YAP-β-catenin axis., PMID:38561411
Chaperones-A New Class of Potential Therapeutic Targets in Alzheimer's Disease., PMID:38542375
Polymorphism in Genes Encoding Adaptor Proteins ST13 and STIP1 and the Risk of Ischemic Stroke: a Pilot Study., PMID:38492099
STUB1 increases adiponectin expression by inducing ubiquitination and degradation of NR2F2, thereby reducing hepatic stellate cell activation and alleviating non-alcoholic fatty liver disease., PMID:38471267
Phosphorylated SHMT2 Regulates Oncogenesis Through m6A Modification in Lung Adenocarcinoma., PMID:38460155
A Chinese Family with Digenic TBP/STUB1 Spinocerebellar Ataxia., PMID:38342844
An Aptamer-Based Nanoflow Cytometry Method for the Molecular Detection and Classification of Ovarian Cancers through Profiling of Tumor Markers on Small Extracellular Vesicles., PMID:38012811
USF2 promotes autophagy and proliferation in chronic lymphocytic leukemia by inhibiting STUB1-induced NFAT5 ubiquitination., PMID:37950051
The potential roles of stress-induced phosphoprotein 1 and connexin 43 in rats with reperfusion arrhythmia., PMID:37904692
ELP2-NLRP3-GSDMD/GSDME-mediated pyroptosis is induced by TNF-α in MC3T3-E1 cells during osteogenic differentiation., PMID:37830762
LINC01226 promotes gastric cancer progression through enhancing cytoplasm-to-nucleus translocation of STIP1 and stabilizing β-catenin protein., PMID:37806517
Extremely low-frequency electromagnetic field induces acetylation of heat shock proteins and enhances protein folding., PMID:37717354
HSP90β Impedes STUB1-Induced Ubiquitination of YTHDF2 to Drive Sorafenib Resistance in Hepatocellular Carcinoma., PMID:37515378
STUB1/CHIP: New insights in cancer and immunity., PMID:37506582
[STIP1 correlates with tumor immune infiltration and prognosis as a potential immunotherapy target: a pan-cancer bioinformatics analysis]., PMID:37488801
Tumor-promoting action of ubiquitin protease 43 in gastric cancer progression through deubiquitination and stabilization of stress-inducible phosphoprotein 1., PMID:37442266
STUB1-mediated ubiquitination regulates the stability of GLUD1 in lung adenocarcinoma., PMID:37416474
Molecular chaperones HSP40, HSP70, STIP1, and HSP90 are involved in stabilization of Cx43., PMID:37187948
Elucidating cellular interactome of chikungunya virus identifies host dependency factors., PMID:37182691
For research use only. Not for human or drug use.
