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Recombinant Human ATAD1 Protein, N-His

Catalog #:   YHN12901 Specific References (44) DATASHEET
Applications: ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Expression system: E. coli
Accession: Q8NBU5
Protein length: Thr33-Asp361
Overview

Catalog No.

YHN12901

Expression system

E. coli

Species

Homo sapiens (Human)

Protein length

Thr33-Asp361

Predicted molecular weight

39.12 kDa

Nature

Recombinant

Endotoxin level

Please contact with the lab for this information.

Purity

>90% as determined by SDS-PAGE.

Accession

Q8NBU5

Applications

ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress

Form

Lyophilized

Storage buffer

Lyophilized from a solution in PBS pH 7.4, 0.02% SKL, 1mM EDTA, 5% Trehalose, 2% Mannitol.

Reconstitution

Reconstitute in sterile water for a stock solution.

Shipping

In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at -20 to -80°C for twelve months from the date of receipt.

Alternative Names

ATAD1, hATAD1, ATPase family AAA domain-containing protein 1, Outer mitochondrial transmembrane helix translocase, Thorase

Data Image
  • SDS-PAGE
    SDS-PAGE for Recombinant Human ATAD1 Protein
References

Cryo-EM structure of AAA + ATPase thorase reveals novel helical filament formation., PMID:40510765

ATAD1 Regulates Neuronal Development and Synapse Formation Through Tuning Mitochondrial Function., PMID:39795902

Mitochondrial YME1L1 governs unoccupied protein translocase channels., PMID:39774271

Cryo-EM Structure of AAA + ATPase Thorase Reveals Novel Helical Filament Formation., PMID:39605435

Analysis of protein trafficking between mitochondria and the endoplasmic reticulum by fluorescence microscopy., PMID:39488373

The ATP-driven extractor ATAD1/Msp1 proof-reads protein translocation into mitochondria., PMID:39089957

ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins., PMID:39024102

circ-ATAD1 as Competing Endogenous RNA for miR-191-5p Forces Non-small Cell Lung Cancer Progression., PMID:38079004

Intrinsic deletion at 10q23.31, including the PTEN gene locus, is aggravated upon CRISPR-Cas9-mediated genome engineering in HAP1 cells mimicking cancer profiles., PMID:37984988

ATAD1 inhibits hepatitis C virus infection by removing the viral TA-protein NS5B from mitochondria., PMID:37789674

The AAA-ATPase Yta4/ATAD1 interacts with the mitochondrial divisome to inhibit mitochondrial fission., PMID:37590302

Neonatal Hypertonia and Progressive Respiratory Failure due to Novel Heterozygous Mutation in ATAD1., PMID:36933275

Proofreading of protein localization mediated by a mitochondrial AAA-ATPase Msp1., PMID:36413760

Collateral deletion of the mitochondrial AAA+ ATPase ATAD1 sensitizes cancer cells to proteasome dysfunction., PMID:36409067

The AAA-ATPase ATAD1 and its partners promote degradation of desmin intermediate filaments in muscle., PMID:36278411

Conserved structural elements specialize ATAD1 as a membrane protein extraction machine., PMID:35550246

CircRNA circ-ATAD1 suppresses miR-618 maturation to participate in colorectal cancer., PMID:35505304

Circ-ATAD1 is overexpressed in osteosarcoma (OS) and suppresses the maturation of miR-154-5p to increase cell invasion and migration., PMID:34857012

ER-SURF: Riding the Endoplasmic Reticulum Surface to Mitochondria., PMID:34502567

The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder., PMID:34351705

CircRNA circ-ATAD1 Is Upregulated in Cervical Squamous Cell Carcinoma and Regulates Cell Proliferation and Apoptosis by Suppressing the Maturation of miR-218., PMID:34254279

Transmembrane dislocases: a second chance for protein targeting., PMID:34147299

Quality control pathways of tail-anchored proteins., PMID:33285177

AMPA Receptor Surface Expression Is Regulated by S-Nitrosylation of Thorase and Transnitrosylation of NSF., PMID:33147468

Mammalian Homologue NME3 of DYNAMO1 Regulates Peroxisome Division., PMID:33126676

Msp1/ATAD1 in Protein Quality Control and Regulation of Synaptic Activities., PMID:32886535

A novel circular RNA, circ-ATAD1, contributes to gastric cancer cell progression by targeting miR-140-3p/YY1/PCIF1 signaling axis., PMID:32169278

Sorting out how Msp1 maintains mitochondrial membrane proteostasis., PMID:31394253

Mitochondrial AAA-ATPase Msp1 detects mislocalized tail-anchored proteins through a dual-recognition mechanism., PMID:30858337

10q23.31 microduplication encompassing PTEN decreases mTOR signalling activity and is associated with autosomal dominant primary microcephaly., PMID:30301738

ATAD1 encephalopathy and stiff baby syndrome: a recognizable clinical presentation., PMID:29659736

Reply: ATAD1 encephalopathy and stiff baby syndrome: a recognizable clinical presentation., PMID:29659731

The AAA + ATPase Thorase is neuroprotective against ischemic injury., PMID:29658368

A homozygous ATAD1 mutation impairs postsynaptic AMPA receptor trafficking and causes a lethal encephalopathy., PMID:29390050

Thorase variants are associated with defects in glutamatergic neurotransmission that can be rescued by Perampanel., PMID:29237760

Msp1 Is a Membrane Protein Dislocase for Tail-Anchored Proteins., PMID:28712723

Synaptic Plasticity onto Dopamine Neurons Shapes Fear Learning., PMID:28103482

Evidence for genetic regulation of the human parieto-occipital 10-Hz rhythmic activity., PMID:27306141

Assembly of Peroxisomal Membrane Proteins via the Direct Pex19p-Pex3p Pathway., PMID:26777132

Role of AAA(+)-proteins in peroxisome biogenesis and function., PMID:26453804

Ganglioside regulation of AMPA receptor trafficking., PMID:25253868

Msp1: patrolling mitochondria for lost proteins., PMID:24916308

Msp1/ATAD1 maintains mitochondrial function by facilitating the degradation of mislocalized tail-anchored proteins., PMID:24843043

The AAA+ ATPase Thorase regulates AMPA receptor-dependent synaptic plasticity and behavior., PMID:21496646

Datasheet
$ 330
Product specifications
100 μg 330 1 mg 1880

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For research use only. Not for human or drug use.

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Recombinant Human ATAD1 Protein, N-His [YHN12901]
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