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Anti-Human GRP78 Antibody (huMAb159)

Catalog #:   VHC84901 Specific References (50) DATASHEET
Host species: Human
Isotype: IgG1, kappa
Applications: ELISA, FCM, IHC, Inhib, WB
Accession: P11021
Overview

Catalog No.

VHC84901

Species reactivity

Human

Host species

Human

Isotype

IgG1, kappa

Clonality

Monoclonal

Target

GRP78, HSPA5

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P11021

Applications

ELISA, FCM, IHC, Inhib, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

huMAb159

Data Image
  • SEC-HPLC
    The purity of this product is >95% as determined by SEC-HPLC.
References

Differential Induction of Endoplasmic Reticulum Stress Signaling by Antibody Isotypes: Implications for Plasma Cell Differentiation., PMID:40285383

GRP78 Nanobody-Directed Immunotoxin Activates Innate Immunity Through STING Pathway to Synergize Tumor Immunotherapy., PMID:40135833

A humanized antibody against mucormycosis targets angioinvasion and augments the host immune response., PMID:40073153

GRP78 in Glioma Progression and Therapy: Implications for Targeted Approaches., PMID:40002794

Celastrol-loaded ginsenoside Rg3 liposomes enhance anti-programmed death ligand 1 immunotherapy by inducing immunogenic cell death in triple-negative breast cancer., PMID:39986227

Design and Cytotoxicity Evaluation of a Cancer-targeting Immunotoxin Based on a Camelid Nanobody-PE Fusion Protein., PMID:39731471

Human Cripto-1 and Cripto-3 Protein Expression in Normal and Malignant Settings That Conflicts with Established Conventions., PMID:39518018

Blood-Brain Barrier Disruption in Neuroimmunological Disease., PMID:39408955

In silico and in vitro evaluation of a PE38 and Nb-based recombinant immunotoxin targeting the GRP78 receptor in cancer cells., PMID:39397264

Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor and GAD65 Antibodies: Case Report and Potential Mechanisms., PMID:39213470

A novel bispecific T-cell engager using the ligand-target csGRP78 against acute myeloid leukemia., PMID:39196413

CD5L up-regulates the TGF-β signaling pathway and promotes renal fibrosis., PMID:39127319

UGT1A7 altered HER2-positive breast cancer response to trastuzumab by affecting epithelial-to-mesenchymal transition: A potential biomarker to identify patients resistant to trastuzumab treatment., PMID:39122832

Small molecules targeting GRP78 mitigate anti-GRP78 autoantibody-mediated tissue factor procoagulant activity in cultured endothelial cells., PMID:39111636

Cobalt(III) prodrug-based nanomedicine for inducing immunogenic cell death and enhancing chemo-immunotherapy., PMID:39033985

Investigating the effect of cGRP78 vaccine against different cancer cells and its role in reducing melanoma metastasis., PMID:39006979

Immunoexpression Pattern of Autophagy-Related Proteins in Human Congenital Anomalies of the Kidney and Urinary Tract., PMID:38999938

Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis., PMID:38906502

The dispensability of VH-VL pairing and the indispensability of VL domain integrity in the IgG1 secretion process., PMID:38756530

Porcine epidemic diarrhea virus E protein induces formation of stress granules and attenuates protein translation through activation of the PERK/eIF2α signaling pathway., PMID:38643723

Endoplasmic Reticulum Stress and Unfolded Protein Response in Vernal Keratoconjunctivitis., PMID:38597723

Enhancing precision medicine: Bispecific antibody-mediated targeted delivery of lipid nanoparticles for potential cancer therapy., PMID:38467208

Intestinal heat shock proteins in metabolic syndrome: Novel mediators of obesity and its comorbidities resolution after metabolic surgery., PMID:38412940

[Blood-brain barrier breakdown and autoimmune cerebellar ataxia]., PMID:38403685

Fatal attractions that trigger inflammation and drive atherosclerotic disease., PMID:38287209

Platelets induce endoplasmic reticulum stress in macrophages in vitro., PMID:38278417

Association of COVID with Mycosis in General., PMID:38251692

[Identification of Melittin-Like Proteins with a Molecular Weight of 67 κDa that Interact with Na^(+)/K^(+)-ATPase]., PMID:38062961

Cell surface GRP78: A potential therapeutic target for high glucose-induced endothelial injury., PMID:38056158

Direct interaction of the molecular chaperone GRP78/BiP with the Newcastle disease virus hemagglutinin-neuraminidase protein plays a vital role in viral attachment to and infection of culture cells., PMID:37920471

Association of maternal thyroid peroxidase antibody during pregnancy with placental morphology and inflammatory and oxidative stress responses., PMID:37810887

The chaperone protein GRP78 released from MPN cells increases the expression of lysyl oxidase in a human stromal cell line., PMID:37757654

Heterologous DNA-prime/protein-boost immunization with a monomeric SARS-CoV-2 spike antigen redundantizes the trimeric receptor-binding domain structure to induce neutralizing antibodies in old mice., PMID:37753087

Mechanistic characterization of disulfide bond reduction of an ERAD substrate mediated by cooperation between ERdj5 and BiP., PMID:37739037

Recent advances in small molecule and peptide inhibitors of glucose-regulated protein 78 for cancer therapy., PMID:37690265

Disturbance of neuron-microglia crosstalk mediated by GRP78 in Neuropsychiatric systemic lupus erythematosus mice., PMID:37365565

XBP1s gene of endoplasmic reticulum stress enhances proliferation and osteogenesis of human periodontal ligament cells., PMID:37329685

HSPA5 Promotes Attachment and Internalization of Porcine Epidemic Diarrhea Virus through Interaction with the Spike Protein and the Endo-/Lysosomal Pathway., PMID:37222617

Cell surface GRP78: a potential mechanism of therapeutic resistant tumors., PMID:37221596

Investigation and development of transient production process for porcine circovirus Type-2 (PCV2) capsid protein in HEK293F cells., PMID:37137401

Extracellular HSPA5 is autocrinally involved in the regulation of neuronal process elongation., PMID:37137223

Immunoexpression Pattern of Autophagy Markers in Developing and Postnatal Kidneys of Dab1-/-(yotari) Mice., PMID:36979337

An antibody that targets cell-surface glucose-regulated protein-78 inhibits expression of inflammatory cytokines and plasminogen activator inhibitors by macrophages., PMID:36947703

Cell surface GRP78 regulates TGFβ1-mediated profibrotic responses via TSP1 in diabetic kidney disease., PMID:36909183

Salvianolic acid A attenuates inflammation-mediated atherosclerosis by suppressing GRP78 secretion of endothelial cells., PMID:36758912

Citrullinated glucose-regulated protein 78 is a candidate target for melanoma immunotherapy., PMID:36544781

Upper gut heat shock proteins HSP70 and GRP78 promote insulin resistance, hyperglycemia, and non-alcoholic steatohepatitis., PMID:36513656

Autoantibody against Tumor-Associated Antigens as Diagnostic Biomarkers in Hispanic Patients with Hepatocellular Carcinoma., PMID:36291095

Paraneoplastic Neuromyelitis Optica Spectrum Disorder Related to Glucose-regulated Protein 78 (GRP78) Autoantibodies in a Patient with Lynch Syndrome-associated Colorectal Cancer., PMID:36288992

Effect of Tauroursodeoxycholic Acid on Inflammation after Ocular Alkali Burn., PMID:36233018

Datasheet
$ 372
Product specifications
100 μg 372 1 mg 1860

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For research use only. Not for human or drug use.

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Anti-Human GRP78 Antibody (huMAb159) [VHC84901]
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