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Anti-Rotavirus A/RV-A VP4 Polyclonal Antibody

Catalog #:   PVV20201 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IF, IHC, WB
Accession: E9BVI4
Overview

Catalog No.

PVV20201

Species reactivity

Human rotavirus A

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Rotavirus A/RV-A VP4 (Leu15-Leu173).

Target

Outer capsid protein VP4, VP4

Purification

Antigen affinity purification.

Accession

E9BVI4

Applications

ELISA, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.

Data Image
References

A rotavirus VP4 or VP7 monoreassortant panel identifies genotypes that are less susceptible to neutralization by systemic antibodies induced by vaccination or natural infection., PMID:40444468

Truncated rotavirus VP4 proteins induce stronger protective immunity compared to P2 - VP8 in animal models., PMID:40194664

VP4-Specific IgA level as a correlate of neutralizing antibody and fecal shedding of porcine rotavirus infection., PMID:40179488

Breast milk delivery of an engineered dimeric IgA protects neonates against rotavirus., PMID:39842610

A single residue switch mediates the broad neutralization of Rotaviruses., PMID:39833145

Chimeric Viruses Enable Study of Antibody Responses to Human Rotaviruses in Mice., PMID:39066309

The synergy of recombinant NSP4 and VP4 from porcine rotavirus elicited a strong mucosal response., PMID:38850894

Antigenic epitope analysis of Pakistani G3 and G9 rotavirus strains compared to vaccine strains revealed multiple amino acid differences., PMID:38759540

Wa-VP4* as a candidate rotavirus vaccine induced homologous and heterologous virus neutralizing antibody responses in mice, pigs, and cynomolgus monkeys., PMID:38670845

Recombinant bivalent subunit vaccine combining truncated VP4 from P[7] and P[23] induces protective immunity against prevalent porcine rotaviruses., PMID:38591886

Novel Universal Recombinant Rotavirus A Vaccine Candidate: Evaluation of Immunological Properties., PMID:38543803

A Viral Protein 4-Based Trivalent Nanoparticle Vaccine Elicited High and Broad Immune Responses and Protective Immunity against the Predominant Rotaviruses., PMID:38353701

Role of Pre-Farrow Natural Planned Exposure of Gilts in Shaping the Passive Antibody Response to Rotavirus A in Piglets., PMID:38140269

Lactobacillus acidophilus Expressing Murine Rotavirus VP8 and Mucosal Adjuvants Induce Virus-Specific Immune Responses., PMID:38140179

Characterization of Rotavirus Strains Responsible for Breakthrough Diarrheal Diseases among Zambian Children Using Whole Genome Sequencing., PMID:38140164

Interaction of species A rotavirus VP4 with the cellular proteins vimentin and actin related protein 2 discovered by a proximity interactome assay., PMID:37991368

Comparative whole genome analysis reveals re-emergence of human Wa-like and DS-1-like G3 rotaviruses after Rotarix vaccine introduction in Malawi., PMID:37305707

Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses., PMID:36185383

Generation and characterization of mouse monoclonal antibodies against the VP4 protein of group A human rotaviruses., PMID:36152816

Phylogenetic analysis of the viral proteins VP4/VP7 of circulating human rotavirus strains in China from 2016 to 2019 and comparison of their antigenic epitopes with those of vaccine strains., PMID:36004332

Rotavirus VP4 Epitope of a Broadly Neutralizing Human Antibody Defined by Its Structure Bound with an Attenuated-Strain Virion., PMID:35924923

Using Species a Rotavirus Reverse Genetics to Engineer Chimeric Viruses Expressing SARS-CoV-2 Spike Epitopes., PMID:35758692

Monoreassortant Rotaviruses of Multiple G Types Are Differentially Neutralized by Sera From Infants Vaccinated With ROTARIX and RotaTeq., PMID:34628500

Phylogenetic analysis of VP7 and VP4 genes of the most predominant human group A rotavirus G12 identified in children with acute gastroenteritis in Himachal Pradesh, India during 2013-2016., PMID:34138482

Equine rotavirus infection., PMID:33776534

Development of Genotype-Specific Anti-Bovine Rotavirus A Immunoglobulin Yolk Based on a Current Molecular Epidemiological Analysis of Bovine Rotaviruses A Collected in Japan during 2017-2020., PMID:33287460

Reverse Genetics Approach for Developing Rotavirus Vaccine Candidates Carrying VP4 and VP7 Genes Cloned from Clinical Isolates of Human Rotavirus., PMID:33087468

In Silico Characterization of Epitopes from Human Rotavirus VP7 Genotype G9 Design for Vaccine Development., PMID:32245310

Thiol/disulfide exchange occurs in rotavirus structural proteins during contact with intestinal villus cell surface., PMID:32180418

VP7 and VP4 genotypes of rotaviruses cocirculating in Iran, 2015 to 2017: Comparison with cogent sequences of Rotarix and RotaTeq vaccine strains before their use for universal mass vaccination., PMID:31774174

Human Neonatal Rotavirus Vaccine (RV3-BB) Produces Vaccine Take Irrespective of Histo-Blood Group Antigen Status., PMID:31763671

Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells., PMID:31403468

The distinct impact of maternal antibodies on the immunogenicity of live and recombinant rotavirus vaccines., PMID:31182323

[Polymerization and evaluation of the protective efficacy of rotavirus VP4* proteins]., PMID:30806058

Development of Stable Rotavirus Reporter Expression Systems., PMID:30541830

The C Terminus of Rotavirus VP4 Protein Contains an Actin Binding Domain Which Requires Cooperation with the Coiled-Coil Domain for Actin Remodeling., PMID:30333172

Multiple Introductions and Antigenic Mismatch with Vaccines May Contribute to Increased Predominance of G12P[8] Rotaviruses in the United States., PMID:30333170

Isolation and characterization of a new candidate human inactivated rotavirus vaccine strain from hospitalized children in Yunnan, China: 2010-2013., PMID:30294607

Design and testing of a highly conserved human rotavirus VP8* immunogenic peptide with potential for vaccine development., PMID:29886031

Expression and characterization of a novel truncated rotavirus VP4 for the development of a recombinant rotavirus vaccine., PMID:29555220

Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoating., PMID:29352319

VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans., PMID:28637924

Expression of bovine rotavirus VP8 and preparation of IgY antibodies against recombinant VP8., PMID:28523920

Genetic and serologic surveillance of rotavirus with P[8] and P[4] genotypes in feces from children in the city of Chihuahua, northern Mexico., PMID:27762426

Reinfection of adult cattle with rotavirus B during repeated outbreaks of epidemic diarrhea., PMID:27408331

Molecular Characterization of Human Rotavirus from Children with Diarrhoeal Disease in Sokoto State, Nigeria., PMID:27051531

Engineering and expression of a human rotavirus candidate vaccine in Nicotiana benthamiana., PMID:26626122

Modeling of the rotavirus group C capsid predicts a surface topology distinct from other rotavirus species., PMID:26524514

Tandem truncated rotavirus VP8* subunit protein with T cell epitope as non-replicating parenteral vaccine is highly immunogenic., PMID:26091081

Characterization of a G1P[8] rotavirus causing an outbreak of gastroenteritis in the Northern Territory, Australia, in the vaccine era., PMID:26038746

Datasheet
$ 200
Product specifications
50 μg 200 100 μg 330

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Anti-Rotavirus A/RV-A VP4 Polyclonal Antibody [PVV20201]
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