Catalog No.
PHN06201
Species reactivity
Human, Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CADM1/SynCAM1 (Asn46-Tyr331).
Target
SgIgSF, Immunoglobulin superfamily member 4, SynCAM, IGSF4A, SYNCAM, TSLC1, Synaptic cell adhesion molecule, IgSF4, Tumor suppressor in lung cancer 1, TSLC-1, CADM1, Spermatogenic immunoglobulin superfamily, Nectin-like protein 2, Cell adhesion molecule 1, NECL2, IGSF4, NECL-2
Purification
Antigen affinity purification.
Accession
Q9BY67
Applications
ELISA, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 4 ℃ for frequent use. Store at -20 ℃ for twelve months from the date of receipt.
Multiple Functions of Cell Adhesion Molecule 1 (CADM1) and Its Role in the Pathogenesis of Cancer and Other Diseases., PMID:40399107
Alternative splicing of CADM1 is associated with endothelial progenitor cell dysfunction in preeclampsia., PMID:39928918
An antibody-drug conjugate for endometrioid carcinoma based on the expression of cell adhesion molecule 1., PMID:39252827
Relief of pain in mice by an antibody with high affinity for cell adhesion molecule 1 on nerves., PMID:39173997
Anti-tumor effect of antibody-drug conjugate targeting cell adhesion molecule 1 on GIST cells representing small intestinal GIST., PMID:39096891
Three candidate SNPs show associations with thyroid-stimulating hormone in euthyroid subjects: Tehran thyroid study., PMID:38932823
Efficient intracellular drug delivery by co-administration of two antibodies against cell adhesion molecule 1., PMID:38782061
Disruption of CADM1-dependent cell-cell adhesion in human oral squamous cell carcinoma cells results in tumor progression, possibly through an increase of MMP-2 and MMP-9 expression., PMID:38030062
Potential Contribution of Cell Adhesion Molecule 1 to the Binding of SARS-CoV-2 Spike Protein to Mouse Nasal Mucosa., PMID:37903481
Concerted Antibody and Antigen Discovery by Differential Whole-cell Phage Display Selections and Multi-omic Target Deconvolution., PMID:37019174
Innate cell markers that predict anti-HIV neutralizing antibody titers in vaccinated macaques., PMID:36167072
Possible Therapeutic Utility of anti-Cell Adhesion Molecule 1 Antibodies for Malignant Pleural Mesothelioma., PMID:35903548
A Fully-Human Antibody Specifically Targeting a Membrane-Bound Fragment of CADM1 Potentiates the T Cell-Mediated Death of Human Small-Cell Lung Cancer Cells., PMID:35805896
Gene methylation of CADM1 and MAL identified as a biomarker of high grade anal intraepithelial neoplasia., PMID:35241698
Trans-homophilic interaction of CADM1 promotes organ infiltration of T-cell lymphoma by adhesion to vascular endothelium., PMID:35213073
A CADM3 variant causes Charcot-Marie-Tooth disease with marked upper limb involvement., PMID:33889941
Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons., PMID:33397712
Short Disordered Epitope of CRTAM Ig-Like V Domain as a Potential Target for Blocking Antibodies., PMID:33233764
Deficiency in the function of inhibitory interneurons contributes to glutamate-associated central sensitization through GABABR2-SynCAM1 signaling in chronic migraine rats., PMID:32931071
CADM1 enhances intestinal barrier function in a rat model of mild inflammatory bowel disease by inhibiting the STAT3 signaling pathway., PMID:32929607
Development of anti-human CADM1 monoclonal antibodies as a potential therapy for adult T-cell leukemia/lymphoma., PMID:32656636
Cell Adhesion Molecule 1 Contributes to Cell Survival in Crowded Epithelial Monolayers., PMID:32527032
Mortality and risk of progression to adult T cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis., PMID:32393644
Prokaryotic Expression of the Immunoglobulin's Domains of CRTAM to Characterize a Monoclonal Antibody., PMID:32300914
Urinary Cell Adhesion Molecule 1 Is a Novel Biomarker That Links Tubulointerstitial Damage to Glomerular Filtration Rates in Chronic Kidney Disease., PMID:31316980
Molecular Profiling of Ulcerative Colitis Subjects from the TURANDOT Trial Reveals Novel Pharmacodynamic/Efficacy Biomarkers., PMID:30901380
Renal ADAM10 and 17: Their Physiological and Medical Meanings., PMID:30460232
Expression of cell adhesion molecule 1 in gastric neck and base glandular cells: Possible involvement in peritoneal dissemination of signet ring cells., PMID:30312702
Isolation of human monoclonal antibodies that bind to two different antigens and are encoded by germline VH and VL genes., PMID:29944883
Clinicopathological analysis in PTCL-NOS with CADM1 expression., PMID:28940014
Normal intrathecal leukocyte cell number and composition do not decrease the incidence of post-lumbar puncture headache., PMID:28778448
A Unique T-Cell Receptor Amino Acid Sequence Selected by Human T-Cell Lymphotropic Virus Type 1 Tax301-309-Specific Cytotoxic T Cells in HLA-A24:02-Positive Asymptomatic Carriers and Adult T-Cell Leukemia/Lymphoma Patients., PMID:28724766
A novel oncolytic adenovirus targeting Wnt signaling effectively inhibits cancer-stem like cell growth via metastasis, apoptosis and autophagy in HCC models., PMID:28698142
Manifestation of osteoblastic phenotypes in the sarcomatous component of epithelial carcinoma and sarcomatoid carcinoma., PMID:28651491
DNA methylation signatures and coagulation factors in the peripheral blood leucocytes of epithelial ovarian cancer., PMID:28637314
Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1., PMID:28628102
Effects of Viola mandshurica on Atherosclerosis and Hepatic Steatosis in ApoE[Formula: see text] via the AMPK Pathway., PMID:28514904
CADM1 mRNA expression and clinicopathological significance in esophageal squamous cell carcinoma tissue., PMID:28510248
Cell adhesion molecule-1 (CADM1) expressed on adult T-cell leukemia/lymphoma cells is not involved in the interaction with macrophages., PMID:28420814
Negative feedback loop of bone resorption by NFATc1-dependent induction of Cadm1., PMID:28414795
miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway., PMID:28335740
Reaching the limits of prognostication in non-small cell lung cancer: an optimized biomarker panel fails to outperform clinical parameters., PMID:28281552
Secretome analysis to elucidate metalloprotease-dependent ectodomain shedding of glycoproteins during neuronal differentiation., PMID:28084684
Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype., PMID:28061383
MPP2 is a postsynaptic MAGUK scaffold protein that links SynCAM1 cell adhesion molecules to core components of the postsynaptic density., PMID:27756895
Performance of CADM1/MAL-methylation analysis for monitoring of women treated for high-grade CIN., PMID:27430395
Excitatory Synaptic Drive and Feedforward Inhibition in the Hippocampal CA3 Circuit Are Regulated by SynCAM 1., PMID:27413156
New Developments in Mast Cell Biology: Clinical Implications., PMID:27316557
CADM1 regulates the G1/S transition and represses tumorigenicity through the Rb-E2F pathway in hepatocellular carcinoma., PMID:27298105
Effect of Cell Adhesion Molecule 1 Expression on Intracellular Granule Movement in Pancreatic α Cells., PMID:27262873
For research use only. Not for human or drug use.
