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Anti-TTN Antibody (R4C55)

Catalog #:   RHP03001 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: IHC
Accession: Q8WZ42
Overview

Catalog No.

RHP03001

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

IHC: 1:100-1:200

Target

0

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8WZ42

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4C55

Data Image
  • Immunohistochemical
    IHC-P analysis of skeletal muscle tissue by TTN antibody (RHP03001). IHC-P was performed using sections of the formalin-fixed paraffin-embedded skeletal muscle tissue;Result: Myocytes are positively stained at the cytoplasm.
References

Facilitating and restraining virus infection using cell-attachable soluble viral receptors., PMID:39480852

Synergistic effect of two human-like monoclonal antibodies confers protection against orthopoxvirus infection., PMID:38627363

TTN truncation variants produce sarcomere-integrating proteins of uncertain functional significance., PMID:38226618

Histone-Specific CD4+ T Cell Plasticity in Active and Quiescent Systemic Lupus Erythematosus., PMID:38111123

Tumor-Associated and Systemic Autoimmunity in Pre-Clinical Breast Cancer among Post-Menopausal Women., PMID:38002248

[A case of anti-acetylcholine receptor antibody-positive ocular myasthenia gravis with anti-titin antibody and anti-Kv1.4 antibody positive inflammatory myopathy]., PMID:37989286

Truncated titin is structurally integrated into the human dilated cardiomyopathic sarcomere., PMID:37962957

The presence of Rickettsia felis in communities in the central highlands of Vietnam., PMID:37793492

Molecular detection of Rickettsia sp. genotype RF2125 from household dogs in the central highlands of Vietnam., PMID:37639804

Muscle and Muscle-like Autoantigen Expression in Myasthenia Gravis Thymus: Possible Molecular Hint for Autosensitization., PMID:36979710

Affimers targeting proteins in the cardiomyocyte Z-disc: Novel tools that improve imaging of heart tissue., PMID:36865889

Apatinib combined with camrelizumab in advanced acral melanoma patients: An open-label, single-arm phase 2 trial., PMID:36753834

Anti-titin antibodies are associated with myocarditis in patients with myasthenia gravis., PMID:36383260

Novel Complement C5 Small-interfering RNA Lipid Nanoparticle Prolongs Graft Survival in a Hypersensitized Rat Kidney Transplant Model., PMID:35749284

[Analysis of clinical characteristics and related genetic variation of juvenile myasthenia gravis]., PMID:35599409

βIV-Spectrin Autoantibodies in 2 Individuals With Neuropathy of Possible Paraneoplastic Origin: A Case Series., PMID:35581007

Efficacy, safety, and immunogenicity of an inactivated, adjuvanted enterovirus 71 vaccine in infants and children: a multiregion, double-blind, randomised, placebo-controlled, phase 3 trial., PMID:35427481

Genetic Characteristics Associated With Drug Resistance in Lung Cancer and Colorectal Cancer Using Whole Exome Sequencing of Cell-Free DNA., PMID:35402275

A bibliometric review of peripartum cardiomyopathy compared to other cardiomyopathies using artificial intelligence and machine learning., PMID:35340600

Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338

Orally-active, clinically-translatable senolytics restore α-Klotho in mice and humans., PMID:35292270

Neoadjuvant PD-1 Blockade Combined With Chemotherapy Followed by Concurrent Immunoradiotherapy in Locally Advanced Anal Canal Squamous Cell Carcinoma Patients: Antitumor Efficacy, Safety and Biomarker Analysis., PMID:35095878

Joint modelling and simulation of M-protein dynamics and progression-free survival for alternative isatuximab dosing with pomalidomide/dexamethasone., PMID:34705283

Myelosuppression in patients treated with 177Lutetium-lilotomab satetraxetan can be predicted with absorbed dose to the red marrow as the only variable., PMID:34425735

Thymoma-associated autoimmune encephalitis with positive Titin antibodies: A case report., PMID:34325343

Ebola Virus Transmission Initiated by Relapse of Systemic Ebola Virus Disease., PMID:33789012

Predicting lung adenocarcinoma prognosis with a novel risk scoring based on platelet-related gene expression., PMID:33619234

Human Leukocyte Antigen Class II associations in late-onset Myasthenia Gravis., PMID:33547763

Reply to: Myopathy in Myasthenia Positive for Antibodies Against MuSK, Lrp4, and Titin., PMID:33281166

Long-term analysis of adalimumab in Japanese patients with moderate to severe hidradenitis suppurativa: Open-label phase 3 results., PMID:33029861

A case of myositis with dropped head syndrome and anti-titin antibody positivity induced by pembrolizumab., PMID:32914675

Interferon-α alters host glycosylation machinery during treated HIV infection., PMID:32827942

Late-onset generalized myasthenia gravis: clinical features, treatment, and outcome., PMID:31811563

Cronos Titin Is Expressed in Human Cardiomyocytes and Necessary for Normal Sarcomere Function., PMID:31587567

The Immune Checkpoint Regulator PDL1 is an Independent Prognostic Biomarker for Biochemical Recurrence in Prostate Cancer Patients Following Adjuvant Hormonal Therapy., PMID:31289580

Titin mutation associated with responsiveness to checkpoint blockades in solid tumors., PMID:31092729

Pembrolizumab-induced Ocular Myasthenia Gravis with Anti-titin Antibody and Necrotizing Myopathy., PMID:30713313

Autoantibodies in acquired myasthenia gravis: Clinical phenotype and immunological correlation., PMID:30693486

MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design., PMID:30075702

Targeting Glycosylation Aberrations to Improve the Efficiency of Cancer Phototherapy., PMID:29952259

Translocation of molecular chaperones to the titin springs is common in skeletal myopathy patients and affects sarcomere function., PMID:28915917

Multiple antibody detection in 'seronegative' myasthenia gravis patients., PMID:28470860

Single nucleotide polymorphisms in the IGF-IRS pathway are associated with outcome in mCRC patients enrolled in the FIRE-3 trial., PMID:28369940

α-B Crystallin Reverses High Diastolic Stiffness of Failing Human Cardiomyocytes., PMID:28242778

T/Tn immunotherapy avoiding immune deviation., PMID:27760846

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease., PMID:25589632

Measurement of a MMP-2 degraded Titin fragment in serum reflects changes in muscle turnover induced by atrophy., PMID:25077715

Antititin antibody in early- and late-onset myasthenia gravis., PMID:24947881

High prevalence of MAP2K1 mutations in variant and IGHV4-34-expressing hairy-cell leukemias., PMID:24241536

Crucial role for Ca2(+)/calmodulin-dependent protein kinase-II in regulating diastolic stress of normal and failing hearts via titin phosphorylation., PMID:23283722

Datasheet

Document Download

Anti-TTN Antibody (R4C55).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-TTN Antibody (R4C55) [RHP03001]
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