Catalog No.
RHN97901
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IHC: 1:200-1:1000
Target
GPR56 NT, GPR56 7TM, ADGRG1 NT, Adhesion G-protein coupled receptor G1, GPR56 subunit beta, TM7LN4, GPR56 extracellular subunit, G-protein coupled receptor 56, ADGRG1, ADGRG1 CT, Protein TM7XN1, GPR56(N), GPR56 C-terminal fragment, TM7XN1, GPR56(C), GPR56, GPR56 seven-transmembrane subunit, GPR56 CT, GPR56 N-terminal fragment, GPR56 subunit alpha
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9Y653
Applications
ELISA, FCM, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4B87
Novel diagnostic biomarker and immune profiling of GPR56+ B cell subsets in systemic lupus erythematosus., PMID:40311320
G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors., PMID:39281883
G protein selectivity profile of GPR56/ADGRG1 and its effect on downstream effectors., PMID:39231834
A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets for breast cancer., PMID:38834774
Mesenchymal Transglutaminase 2 Activates Epithelial ADAM17: Link to G-Protein-Coupled Receptor 56 (ADGRG1) Signalling., PMID:38397010
Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane., PMID:36979492
Transcriptome analysis of Homo sapiens and Mus musculus reveals mechanisms of CD8+ T cell exhaustion caused by different factors., PMID:36084049
Single cell sequencing identifies clonally expanded synovial CD4+ TPH cells expressing GPR56 in rheumatoid arthritis., PMID:35831277
A correlation study of adhesion G protein-coupled receptors as potential therapeutic targets in Uterine Corpus Endometrial cancer., PMID:35413679
Adhesion GPCR GPR56 Expression Profiling in Human Tissues., PMID:34944065
Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion., PMID:33837725
In Silico Approach in Designing a Novel Multi-Epitope Vaccine Candidate against Non-Small Cell Lung Cancer with Overexpressed G Protein-Coupled Receptor 56., PMID:32856858
GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism., PMID:31444231
The Activation and Signaling Mechanisms of GPR56/ADGRG1 in Melanoma Cell., PMID:30135857
High levels of soluble GPR56/ADGRG1 are associated with positive rheumatoid factor and elevated tumor necrosis factor in patients with rheumatoid arthritis., PMID:28690029
GPR56/ADGRG1 Activation Promotes Melanoma Cell Migration via NTF Dissociation and CTF-Mediated Gα12/13/RhoA Signaling., PMID:27818281
GPR56 contributes to the development of acute myeloid leukemia in mice., PMID:27063597
Agonistic antibodies reveal the function of GPR56 in human glioma U87-MG cells., PMID:25832639
Expression and immunoaffinity purification of recombinant soluble human GPR56 protein for the analysis of GPR56 receptor shedding by ELISA., PMID:25437104
GPR56 as a novel marker identifying the CD56dull CD16+ NK cell subset both in blood stream and in inflamed peripheral tissues., PMID:20008459
GPR56 is highly expressed in neural stem cells but downregulated during differentiation., PMID:19525879
GPR56 is a GPCR that is overexpressed in gliomas and functions in tumor cell adhesion., PMID:15674329
Dynamic regulation of a GPCR-tetraspanin-G protein complex on intact cells: central role of CD81 in facilitating GPR56-Galpha q/11 association., PMID:15004227
For research use only. Not for human or drug use.
