Catalog No.
RHN95601
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
B-cell adapter molecule of 32 kDa, Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide, BAM32, hDAPP1, DAPP1, B lymphocyte adapter protein Bam32
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9UN19
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4B48
Human T-bet governs the generation of a distinct subset of CD11chighCD21low B cells., PMID:35867801
Multiple Changes of Gene Expression and Function Reveal Genomic and Phenotypic Complexity in SLE-like Disease., PMID:26057447
The B cell adaptor molecule Bam32 is critically important for optimal antibody response and resistance to Trypanosoma congolense infection in mice., PMID:25875604
High-dimensional gene expression profiling studies in high and low responders to primary smallpox vaccination., PMID:22949304
Bam32/DAPP1 promotes B cell adhesion and formation of polarized conjugates with T cells., PMID:20495066
Regulation of B-cell entry into the cell cycle., PMID:18759927
Bam32: a novel mediator of Erk activation in T cells., PMID:18448454
Regulation of B-lymphocyte activation by the PH domain adaptor protein Bam32/DAPP1., PMID:17371232
Regulation of phosphoinositide 3-kinase signaling by oxidants: hydrogen peroxide selectively enhances immunoreceptor-induced recruitment of phosphatidylinositol (3,4) bisphosphate-binding PH domain proteins., PMID:17215104
[Identification of proteins interacting with adaptor protein Bam32]., PMID:15989784
Role of the adaptor proteins Bam32, TAPP1 and TAPP2 in lymphocyte activation., PMID:15626471
The B lymphocyte adaptor molecule of 32 kilodaltons (Bam32) regulates B cell antigen receptor internalization., PMID:15494510
Two distinct waves of membrane-proximal B cell antigen receptor signaling differentially regulated by Src homology 2-containing inositol polyphosphate 5-phosphatase., PMID:14688341
Branches of the B cell antigen receptor pathway are directed by protein conduits Bam32 and Carma1., PMID:14614850
The B cell SH2/PH domain-containing adaptor Bam32/DAPP1 is required for T cell-independent II antigen responses., PMID:14588241
Bam32 links the B cell receptor to ERK and JNK and mediates B cell proliferation but not survival., PMID:14563325
TAPP1 and TAPP2 are targets of phosphatidylinositol 3-kinase signaling in B cells: sustained plasma membrane recruitment triggered by the B-cell antigen receptor., PMID:12101241
Src family kinases mediate receptor-stimulated, phosphoinositide 3-kinase-dependent, tyrosine phosphorylation of dual adaptor for phosphotyrosine and 3-phosphoinositides-1 in endothelial and B cell lines., PMID:11524430
DAPP1 undergoes a PI 3-kinase-dependent cycle of plasma-membrane recruitment and endocytosis upon cell stimulation., PMID:11102801
A novel B lymphocyte-associated adaptor protein, Bam32, regulates antigen receptor signaling downstream of phosphatidylinositol 3-kinase., PMID:10770799
For research use only. Not for human or drug use.
