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Anti-CTNNBL1 Antibody (R4B19)

Catalog #:   RHN94003 Specific References (12) DATASHEET
Host species: Mouse
Isotype: IgG2a
Applications: ELISA, FCM, IF, IHC, WB
Accession: Q8WYA6
Overview

Catalog No.

RHN94003

Species reactivity

Human

Host species

Mouse

Isotype

IgG2a

Clonality

Monoclonal

Tested applications

ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:50-1:200, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Beta-catenin-like protein 1, Testis development protein NYD-SP19, C20orf33, NAP, Nuclear-associated protein, CTNNBL1

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8WYA6

Applications

ELISA, FCM, IF, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4B19

Data Image
  • Flow Cytometry
    Flow cytometric analysis of HL-60 cells using CTNNBL1 mouse mAb (green) and negative control (red).
  • Immunofluorescence
    Immunofluorescence analysis of Hela cells using CTNNBL1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human rectum cancer tissues using CTNNBL1 mouse mAb with DAB staining.
  • Western blot
    Western blot analysis using CTNNBL1 mouse mAb against Hela (1) cell lysate.
References

Alternative splicing in ovarian cancer., PMID:39425166

There is no gene for CVID - novel monogenetic causes for primary antibody deficiency., PMID:34153571

Unfolding the Role of Splicing Factors and RNA Debranching in AID Mediated Antibody Diversification., PMID:32924658

Disease-associated CTNNBL1 mutation impairs somatic hypermutation by decreasing nuclear AID., PMID:32484799

Activation-induced cytidine deaminase (AID) is localized to subnuclear domains enriched in splicing factors., PMID:24434356

Structural and mutational analysis reveals that CTNNBL1 binds NLSs in a manner distinct from that of its closest armadillo-relative, karyopherin α., PMID:24269683

The structure of full-length human CTNNBL1 reveals a distinct member of the armadillo-repeat protein family., PMID:23897482

A combined nuclear and nucleolar localization motif in activation-induced cytidine deaminase (AID) controls immunoglobulin class switching., PMID:23183374

CTNNBL1 is a novel nuclear localization sequence-binding protein that recognizes RNA-splicing factors CDC5L and Prp31., PMID:21385873

Cutting edge: CTNNBL1 is dispensable for Ig class switch recombination., PMID:20585033

Regulating antibody diversity: taming a mutagen., PMID:18775319

Interaction between antibody-diversification enzyme AID and spliceosome-associated factor CTNNBL1., PMID:18722174

Datasheet
$ 220
Product specifications
50 μg 220 100 μg 350

Contact Information

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Mail: support@antibodysystem.com

Distributor list

For research use only. Not for human or drug use.

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Anti-CTNNBL1 Antibody (R4B19) [RHN94003]
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