Catalog No.
RHN93301
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400
Target
GATA6, GATA-binding factor 6, Transcription factor GATA-6
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q92908
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4B08
Redefining phenotypic intratumor heterogeneity of pancreatic ductal adenocarcinoma: a bottom-up approach., PMID:39935174
Immunohistochemical Analysis of GATA2 Expression in Endometrium and its Relationship with Hormone Receptor Expression in Benign and Premalignant Endometrial Disorders., PMID:39443360
Monitoring tumour resistance to the BRAF inhibitor combination regimen in colorectal cancer patients via circulating tumour DNA., PMID:36202008
Peritoneal GATA6+ macrophage drives hepatic immunopathogenesis and maintains the Treg cell niche in the liver., PMID:35689656
The Stemness-High Human Colorectal Cancer Cells Promote Angiogenesis by Producing Higher Amounts of Angiogenic Cytokines via Activation of the Egfr/Akt/Nf-κB Pathway., PMID:33573006
Metabolic pathways underlying GATA6 regulating Trastuzumab resistance in Gastric Cancer cells based on untargeted metabolomics., PMID:33173435
A NONSENSE GATA6 MUTATION EXPLAINS HISTORY OF CONGENITAL HEART DEFECTS AND 10 YEARS OF POORLY-CONTROLLED DIABETES LACKING DKA IN A NON-OBESE 30 YEAR-OLD INCIDENTALLY FOUND TO HAVE PANCREATIC HYPOPLASIA., PMID:32524025
Case report: adult onset diabetes with partial pancreatic agenesis and congenital heart disease due to a de novo GATA6 mutation., PMID:32245430
Loss of the SWI/SNF-ATPase subunit members SMARCF1 (ARID1A), SMARCA2 (BRM), SMARCA4 (BRG1) and SMARCB1 (INI1) in oesophageal adenocarcinoma., PMID:31906887
Aberrant CD137 ligand expression induced by GATA6 overexpression promotes tumor progression in cutaneous T-cell lymphoma., PMID:30194255
GATA6 phosphorylation by Erk1/2 propels exit from pluripotency and commitment to primitive endoderm., PMID:29454706
lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab resistance via Wnt/β-catenin signaling., PMID:29035371
Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development., PMID:28196600
Polymer microfiber meshes facilitate cardiac differentiation of c-kit(+) human cardiac stem cells., PMID:27481582
Assessment of cell lineages and cell death in blastocysts by immunostaining., PMID:25287346
The transcription factor GATA6 enables self-renewal of colon adenoma stem cells by repressing BMP gene expression., PMID:24952462
GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development., PMID:24929016
Tissue-specific signals control reversible program of localization and functional polarization of macrophages., PMID:24792964
CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development., PMID:24036311
Influence of activin A supplementation during human embryonic stem cell derivation on germ cell differentiation potential., PMID:23829223
Preferential emergence of cell types expressing markers for primitive endoderm lineages in mouse embryonic stem cells expressing exogenous EGAM1 homeoprotein., PMID:22608553
TAp63 is important for cardiac differentiation of embryonic stem cells and heart development., PMID:21898690
GATA6 promotes angiogenic function and survival in endothelial cells by suppression of autocrine transforming growth factor beta/activin receptor-like kinase 5 signaling., PMID:21127043
Heparan sulfation-dependent fibroblast growth factor signaling maintains embryonic stem cells primed for differentiation in a heterogeneous state., PMID:19937756
Identification of mesenchymal stem cell (MSC)-transcription factors by microarray and knockdown analyses, and signature molecule-marked MSC in bone marrow by immunohistochemistry., PMID:19228201
Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6., PMID:18454176
Specific GATA-binding elements in the GnRH promoter are required for gene expression pulse activity: role of GATA-4 and GATA-5 in this intermittent process., PMID:18259093
Expression of CLMP, a novel tight junction protein, is mediated via the interaction of GATA with the Kruppel family proteins, KLF4 and Sp1, in mouse TM4 Sertoli cells., PMID:17620326
BMPs regulate differentiation of a putative visceral endoderm layer within human embryonic stem-cell-derived embryoid bodies., PMID:17464352
Histological and culture studies with respect to ABCG2 expression support the existence of a cancer cell hierarchy in human hepatocellular carcinoma., PMID:17456779
Leukemia inhibitory factor induces endothelial differentiation in cardiac stem cells., PMID:16407199
Codon 12 region of mouse K-ras gene is the site for in vitro binding of transcription factors GATA-6 and NF-Y., PMID:16271038
Association of the transcriptional corepressor TIF1beta with heterochromatin protein 1 (HP1): an essential role for progression through differentiation., PMID:15342492
Sp and GATA factors are critical for Apolipoprotein AI downstream enhancer activity in human HepG2 cells., PMID:14659877
Widespread expression of an extended peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of RNA and protein expression domains., PMID:14516673
Widespread expression of an extended peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of RNA and protein expression domains., PMID:12617850
[Pulmonary carcinogenesis susceptibility-associated single-nucleotide polymorphisms in K-ras intron 2 affect the binding of factor Gata-6 but not gene expression]., PMID:12391845
Thrombin stimulation of the vascular cell adhesion molecule-1 promoter in endothelial cells is mediated by tandem nuclear factor-kappa B and GATA motifs., PMID:11590177
GATA DNA-binding protein expressed in mouse I-10 Leydig testicular tumor cells., PMID:11327717
GATA family transcription factors activate lactase gene promoter in intestinal Caco-2 cells., PMID:11123198
A GATA binding site is involved in the regulation of 15-lipoxygenase-1 expression in human colorectal carcinoma cell line, caco-2., PMID:10675566
GATA-6 activates transcription of surfactant protein A., PMID:10625644
Cooperative interaction between GATA-4 and GATA-6 regulates myocardial gene expression., PMID:10330176
Gastric GATA-6 DNA-binding protein: proteolysis induced by cAMP., PMID:9188781
For research use only. Not for human or drug use.
