Catalog No.
RHN93001
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Tested applications
ELISA: 1:10000, FCM: 1:200-1:400, IF: 1:200-1:1000, IHC: 1:200-1:1000
Target
Inner centromere protein, INCENP
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q9NQS7
Applications
ELISA, FCM, IF, IHC
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.05% Sodium Azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
R4B05
Synthetic Antibodies Detect Distinct Cellular States of Chromosome Passenger Complex Proteins., PMID:35469831
Targeting hepatocarcinogenesis model in C56BL6 mice with pan-aurora kinase inhibitor Danusertib., PMID:29581770
Analysis of HDACi-Induced Changes in Chromosomal Passenger Complex Localization., PMID:27761812
Xtr, a plural tudor domain-containing protein, is involved in the translational regulation of maternal mRNA during oocyte maturation in Xenopus laevis., PMID:22889276
Anti-CENPI autoantibodies in scleroderma patients with features of autoimmune liver diseases., PMID:21888900
Misregulation of mitotic chromosome segregation in a new type of autosomal recessive primary microcephaly., PMID:21857152
Genetic disruption of aurora B uncovers an essential role for aurora C during early mammalian development., PMID:21613325
PAR, a protein involved in the cell cycle, is functionally related to chromosomal passenger proteins., PMID:21225229
Spatio-temporal composition of the mitotic Chromosomal Passenger Complex detected using in situ proximity ligation assay., PMID:21051298
Borealin regulates bipolar spindle formation but may not act as chromosomal passenger during mouse oocyte meiosis., PMID:20515770
ICIS and Aurora B coregulate the microtubule depolymerase Kif2a., PMID:19327998
Perturbation of Incenp function impedes anaphase chromatid movements and chromosomal passenger protein flux at centromeres., PMID:18784935
Identification of a novel mitotic phosphorylation motif associated with protein localization to the mitotic apparatus., PMID:17971412
Centromere RNA is a key component for the assembly of nucleoproteins at the nucleolus and centromere., PMID:17623812
Chromosomal enrichment and activation of the aurora B pathway are coupled to spatially regulate spindle assembly., PMID:17199039
Essential roles for cohesin in kinetochore and spindle function in Xenopus egg extracts., PMID:17158911
Direct association with inner centromere protein (INCENP) activates the novel chromosomal passenger protein, Aurora-C., PMID:15316025
An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin., PMID:12919681
Survivin is required for stable checkpoint activation in taxol-treated HeLa cells., PMID:12783991
Pericentric heterochromatin becomes enriched with H2A.Z during early mammalian development., PMID:12660166
Proteomic analysis of human metaphase chromosomes reveals topoisomerase II alpha as an Aurora B substrate., PMID:12466558
Anaphase onset does not require the microtubule-dependent depletion of kinetochore and centromere-binding proteins., PMID:12235289
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and phosphorylation., PMID:12221116
CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis., PMID:11756469
Human INCENP colocalizes with the Aurora-B/AIRK2 kinase on chromosomes and is overexpressed in tumour cells., PMID:11453556
INCENP binds directly to tubulin and requires dynamic microtubules to target to the cleavage furrow., PMID:11139336
Human centromeres and neocentromeres show identical distribution patterns of >20 functionally important kinetochore-associated proteins., PMID:10607828
Neocentromere formation in a stable ring 1p32-p36.1 chromosome., PMID:10593999
Molecular analysis of the INCENPs (inner centromere proteins): separate domains are required for association with microtubules during interphase and with the central spindle during anaphase., PMID:8408220
Proteins of the inner and outer centromere of mitotic chromosomes., PMID:2698830
The inner centromere protein (INCENP) antigens: movement from inner centromere to midbody during mitosis., PMID:3316246
For research use only. Not for human or drug use.
