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Anti-NKX3-1 Antibody (R4A82)

Catalog #:   RHN91601 Specific References (41) DATASHEET
Host species: Mouse
Isotype: IgG2b
Applications: FCM, IHC, WB
Accession: Q99801
Overview

Catalog No.

RHN91601

Species reactivity

Human

Host species

Mouse

Isotype

IgG2b

Clonality

Monoclonal

Tested applications

FCM: 1:200-1:400, IHC: 1:200-1:1000, WB: 1:500-1:2000

Target

Homeobox protein Nkx-3.1, NKX3.1, Homeobox protein NK-3 homolog A, NKX3-1, NKX3A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q99801

Applications

FCM, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4A82

Data Image
  • Flow Cytometry
    Flow cytometric analysis of PC-3 cells using anti-NKX3A mAb (green) and negative control (purple).
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human prostata tissues (A, B) using anti-NKX3A antibody with DAB staining.
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human Liver tissues using NKX3A mAb
  • Western blot
    Western blot analysis using NKX3A mouse mAb against LNCaP (1) cell lysate.
References

Accelerating histopathology workflows with generative AI-based virtually multiplexed tumour profiling., PMID:39309216

Characterization of HOXB13 expression patterns in localized and metastatic castration-resistant prostate cancer., PMID:37850574

Immunohistochemical Characterization of a Large Cohort of Triple Negative Breast Cancer., PMID:37306115

[Expression and diagnostic value of NKX3.1 and NKX2.2 in mesenchymal chondrosarcoma]., PMID:35152629

[Extraskeletal mesenchymal chondrosarcoma in central nerve system: a clinicopathological analysis]., PMID:34619870

Metastatic Carcinoma of Prostate as a Mimicker of SAPHO Syndrome., PMID:33985979

Diagnostic Immunohistochemistry of Soft Tissue and Bone Tumors: An Update on Biomarkers That Correlate with Molecular Alterations., PMID:33921435

Confirmation of NKX3-1 Expression in EWSR1-NFATC2 Sarcoma and Mesenchymal Chondrosarcoma Using Monoclonal Antibody Immunohistochemistry, RT-PCR, and RNA In Situ Hybridization., PMID:33443863

Tumor Suppressive Maspin-Sensitized Prostate Cancer to Drug Treatment Through Negative Regulating Androgen Receptor Expression., PMID:33195208

Utility of NKX3.1 immunohistochemistry in the differential diagnosis of seminal vesicles versus prostatic tissue in needle biopsy., PMID:33126153

NKX3.1 immunoreactivity is not identified in mesenchymal chondrosarcoma: a 25-case cohort study., PMID:32779239

Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases., PMID:32514122

Immunohistochemical Reactivity of Prostate-Specific Markers for Salivary Duct Carcinoma., PMID:31865345

The Homeodomain Transcription Factor NKX3.1 Modulates Bladder Outlet Obstruction Induced Fibrosis in Mice., PMID:31781523

NKX3.1 and Prostein Expression in Testicular Tissue and Sex Cord-stromal Tumors., PMID:31498176

Adenocarcinoma of the Rete Testis: Clinicopathologic and Immunohistochemical Characterization of 6 Cases and Review of the Literature., PMID:30676333

Prostate Cancer Disseminated Tumor Cells are Rarely Detected in the Bone Marrow of Patients with Localized Disease Undergoing Radical Prostatectomy across Multiple Rare Cell Detection Platforms., PMID:29339080

Vasitis nodosa and related lesions: a modern immunohistochemical staining profile with special emphasis on novel diagnostic dilemmas., PMID:29241741

Performance of different prostate specific antibodies in the cytological diagnosis of metastatic prostate adenocarcinoma., PMID:28888085

A Polyclonal Antibody to NKX3.1 Identifies Fungal Organisms From the Esophagus., PMID:28777145

Ornithine Decarboxylase Activity Is Required for Prostatic Budding in the Developing Mouse Prostate., PMID:26426536

Detecting metastatic prostate carcinoma in pelvic lymph nodes following neoadjuvant hormone therapy: the eyes have it!, PMID:26018610

Metastatic carcinoma of unknown primary: diagnostic approach using immunohistochemistry., PMID:25844674

Prostate adenocarcinomas aberrantly expressing p63 are molecularly distinct from usual-type prostatic adenocarcinomas., PMID:25216229

Best practices recommendations in the application of immunohistochemistry in the prostate: report from the International Society of Urologic Pathology consensus conference., PMID:25029122

Essential roles of epithelial bone morphogenetic protein signaling during prostatic development., PMID:24731097

Alterations of C-MYC, NKX3.1, and E-cadherin expression in canine prostate carcinogenesis., PMID:24030851

4FISH-IF, a four-color dual-gene FISH combined with p63 immunofluorescence to evaluate NKX3.1 and MYC status in prostate cancer., PMID:23640976

Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer., PMID:22986532

Inflammation-mediated abrogation of androgen signaling: an in vitro model of prostate cell inflammation., PMID:22911881

Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice., PMID:20940396

Effect of Ack1 tyrosine kinase inhibitor on ligand-independent androgen receptor activity., PMID:20623637

NKX3.1 as a marker of prostatic origin in metastatic tumors., PMID:20588175

Specific detection of prostate cancer cells in urine by multiplex immunofluorescence cytology., PMID:19368959

Stromal transforming growth factor-beta signaling mediates prostatic response to androgen ablation by paracrine Wnt activity., PMID:18559517

Evidence that phosphorylation of the RNA polymerase II carboxyl-terminal repeats is similar in yeast and humans., PMID:16012166

Structural and functional analysis of domains mediating interaction between NKX-3.1 and PDEF., PMID:15523673

A telomerase-immortalized primary human prostate cancer clonal cell line with neoplastic phenotypes., PMID:15375556

Analysis of androgen regulated homeobox gene NKX3.1 during prostate carcinogenesis., PMID:15311057

Expression, specificity and immunotherapy potential of prostate-associated genes in murine cell lines., PMID:11760786

Loss of NKX3.1 expression in human prostate cancers correlates with tumor progression., PMID:11085535

Datasheet

Document Download

Anti-NKX3-1 Antibody (R4A82).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-NKX3-1 Antibody (R4A82) [RHN91601]
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