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Anti-PRAK Antibody (R4A71)

Catalog #:   RHN90701 Specific References (50) DATASHEET
Host species: Mouse
Isotype: IgG1
Applications: IHC
Accession: Q8IW41
Overview

Catalog No.

RHN90701

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Tested applications

IHC: 1:200-1:1000

Target

MAPKAP-K5, MAPKAPK5, MAPKAP kinase 5, MAPKAPK-5, p38-regulated/activated protein kinase, MK5, PRAK, MK-5, MAPK-activated protein kinase 5, MAP kinase-activated protein kinase 5

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q8IW41

Applications

IHC

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 0.05% Sodium Azide.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

R4A71

Data Image
  • Immunohistochemical
    Immunohistochemical analysis of paraffin-embedded human liver carcinoma (A), esophagus carcinoma (B), normal spleen tissue(C), breast carcinoma (D), showing nuclear and cytoplasmic localization using PRAK mouse mAb with DAB staining.
References

Immunologic Predictors of Vaccine Responsiveness in Patients With Lymphoma and Chronic Lymphocytic Leukemia., PMID:39052709

VLP-ELISA for the Detection of IgG Antibodies against Spike, Envelope, and Membrane Antigens of SARS-CoV-2 in Indian Population., PMID:37112655

Autoantibodies targeting cytokines and connective tissue disease autoantigens are common in acute non-SARS-CoV-2 infections., PMID:35075455

PRAK-03202: A triple antigen virus-like particle vaccine candidate against SARS CoV-2., PMID:34632131

Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy., PMID:34522051

TNFRSF13B genotypes control immune-mediated pathology by regulating the functions of innate B cells., PMID:34283811

The Future of Blood Testing Is the Immunome., PMID:33790897

IgV somatic mutation of human anti-SARS-CoV-2 monoclonal antibodies governs neutralization and breadth of reactivity., PMID:33769311

Longitudinal Analysis Reveals Distinct Antibody and Memory B Cell Responses in SARS-CoV2 Naïve and Recovered Individuals Following mRNA Vaccination., PMID:33688691

New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19., PMID:33532787

The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans., PMID:32353250

The concentration of fetal red blood cells in first-trimester pregnant women undergoing uterine aspiration is below the calculated threshold for Rh sensitization., PMID:32135125

Dramatic increase in gene mutational burden after transformation of follicular lymphoma into TdT+ B-lymphoblastic leukemia/lymphoma., PMID:31776129

Declining hepatitis E virus antibody prevalence in Phnom Penh, Cambodia during 1996-2017., PMID:30309396

Analytical and field evaluation of the Biocentric Generic HCV assay on open polyvalent PCR platforms in France and Cambodia., PMID:30245364

Massive Iatrogenic Outbreak of Human Immunodeficiency Virus Type 1 in Rural Cambodia, 2014-2015., PMID:29211835

Hepatitis E virus antibody prevalence, RNA frequency, and genotype among blood donors in Cambodia (Southeast Asia)., PMID:27480100

Discrimination of germline V genes at different sequencing lengths and mutational burdens: A new tool for identifying and evaluating the reliability of V gene assignment., PMID:26529062

Low frequency of acute hepatitis E virus (HEV) infections but high past HEV exposure in subjects from Cambodia with mild liver enzyme elevations, unexplained fever or immunodeficiency due to HIV-1 infection., PMID:26370310

Can immune thrombocytopenia be cured with medical therapy?, PMID:25793364

The restricted DH gene reading frame usage in the expressed human antibody repertoire is selected based upon its amino acid content., PMID:23630353

Rituximab therapy for primary Sjögren's syndrome: an open-label clinical trial and mechanistic analysis., PMID:23334994

Adoptive transfer of autologous T cells improves T-cell repertoire diversity and long-term B-cell function in pediatric patients with neuroblastoma., PMID:23092876

Rituximab-treated patients have a poor response to influenza vaccination., PMID:23064976

Rottlerin-mediated inhibition of Chlamydia trachomatis growth and uptake of sphingolipids is independent of p38-regulated/activated protein kinase (PRAK)., PMID:22970301

Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens., PMID:22127758

A prospective study of influenza vaccination and a comparison of immunologic parameters in children and adults with chromosome 22q11.2 deletion syndrome (digeorge syndrome/velocardiofacial syndrome)., PMID:21863400

Selection of individual VH genes occurs at the pro-B to pre-B cell transition., PMID:21746964

Alternative mechanisms of receptor editing in autoreactive B cells., PMID:21471456

Comment on "Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs"., PMID:20647589

Violations of the 12/23 rule at the mouse immunoglobulin kappa locus, including V kappa-V kappa rearrangement., PMID:19467709

Developmental acquisition of the Lyn-CD22-SHP-1 inhibitory pathway promotes B cell tolerance., PMID:19380785

Antibody-mediated rejection in heart transplant recipients: potential efficacy of B-cell depletion and antibody removal., PMID:18365409

B cell monitoring of transplant patients treated with anti-CD20., PMID:18365400

Editing and escape from editing in anti-DNA B cells., PMID:18310318

Variability in the biological response to anti-CD20 B cell depletion in systemic lupus erythaematosus., PMID:18250115

B lymphocyte-directed immunotherapy promotes long-term islet allograft survival in nonhuman primates., PMID:17965721

Preformed donor-directed anti-HLA-DP antibodies may be an impediment to successful kidney transplantation., PMID:17956891

Consequences of receptor editing at the lambda locus: multireactivity and light chain secretion., PMID:16847259

Development and selection of edited B cells in B6.56R mice., PMID:16709848

Exogenous and endogenous TLR ligands activate anti-chromatin and polyreactive B cells., PMID:16709806

p38 mitogen-activated protein kinase (MAPK) first regulates filamentous actin at the 8-16-cell stage during preimplantation development., PMID:15850458

p38 MAPK signaling during murine preimplantation development., PMID:15031106

Regulation of anti-phosphatidylserine antibodies., PMID:12594946

Editors and editing of anti-DNA receptors., PMID:11754816

Somatic mutation and light chain rearrangement generate autoimmunity in anti-single-stranded DNA transgenic MRL/lpr mice., PMID:10477553

Editing disease-associated autoantibodies., PMID:9052841

Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing., PMID:8777720

Light chain replacement: a new model for antibody gene rearrangement., PMID:7629511

Light chain editing in kappa-deficient animals: a potential mechanism of B cell tolerance., PMID:7964462

Datasheet

Document Download

Anti-PRAK Antibody (R4A71).pdf

 

$ 220
Product specifications
50 μg 220 100 μg 350

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Anti-PRAK Antibody (R4A71) [RHN90701]
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